2021
Can Propofol Be Used to Assess the Presence of the Rectoanal Inhibitory Reflex During Anorectal Manometry Studies?
Arbizu RA, Amicangelo M, Rodriguez L, Nurko S. Can Propofol Be Used to Assess the Presence of the Rectoanal Inhibitory Reflex During Anorectal Manometry Studies? Journal Of Pediatric Gastroenterology And Nutrition 2021, 74: 33-37. PMID: 34478251, DOI: 10.1097/mpg.0000000000003283.Peer-Reviewed Original ResearchMeSH KeywordsAnal CanalChildConstipationFemaleHumansMaleManometryPropofolProspective StudiesRectumReflexConceptsIntra-anal pressuresRectoanal inhibitory reflexAnorectal manometryInhibitory reflexAbsent rectoanal inhibitory reflexInternal anal sphincter relaxationNormal rectoanal inhibitory reflexAnal sphincter relaxationAnorectal manometry studyBalloon distentionIAS relaxationSpinal neuropathyIntractable constipationObstructive symptomsSphincter relaxationProspective studyAnesthesia inductionManometry studiesPatientsPropofolDisease repairLatency timeConstipationAnesthesiaReflex
2020
Evaluation of Fecal Incontinence in Pediatric Functional Constipation
Morera C, Nurko S, Rodriguez L. Evaluation of Fecal Incontinence in Pediatric Functional Constipation. Journal Of Pediatric Gastroenterology And Nutrition 2020, 72: 361-365. PMID: 33560756, DOI: 10.1097/mpg.0000000000002978.Peer-Reviewed Original ResearchConceptsPediatric functional constipationFecal incontinenceFunctional constipationColonic manometryMedian anal resting pressureAnal resting pressureMore patientsResting pressureAbnormal studiesConventional therapyMale genderTreatment outcomesClinical dataConstipationNormal studiesTherapy responseMeal responseIncontinencePatientsMultivariate analysisMotility studiesTherapyNormal armLow responseManometry
2012
Internal anal sphincter relaxation associated with bisacodyl‐induced colonic high amplitude propagating contractions in children with constipation: a colo‐anal reflex?
Rodriguez L, Siddiqui A, Nurko S. Internal anal sphincter relaxation associated with bisacodyl‐induced colonic high amplitude propagating contractions in children with constipation: a colo‐anal reflex? Neurogastroenterology & Motility 2012, 24: 1023-e545. PMID: 22757618, PMCID: PMC3465462, DOI: 10.1111/j.1365-2982.2012.01965.x.Peer-Reviewed Original ResearchConceptsHigh-amplitude peristaltic contractionsInternal anal sphincter relaxationAnal sphincter relaxationIAS relaxationSphincter relaxationAnal residual pressureManometry tracingsDefecation disordersConstipated childrenAnal relaxationHepatic flexureResting pressureDistal colonPeristaltic contractionsColonAbstractTextConstipationContraction propagationReflexChildrenImportant proportionContractionMost casesPatientsBisacodyl
2008
Botulinum toxin for the treatment of chronic constipation in children with internal anal sphincter dysfunction
Irani K, Rodriguez L, Doody DP, Goldstein AM. Botulinum toxin for the treatment of chronic constipation in children with internal anal sphincter dysfunction. Pediatric Surgery International 2008, 24: 779-783. PMID: 18443801, DOI: 10.1007/s00383-008-2171-3.Peer-Reviewed Original ResearchConceptsInternal anal sphincter dysfunctionAnal sphincter dysfunctionIntrasphincteric injectionSphincter dysfunctionIntractable constipationPediatric patientsBotulinum toxinIAS dysfunctionAbnormal anorectal manometryRectoanal inhibitory reflexTreatment of constipationDuration of effectChronic constipationPostoperative incontinenceRefractory constipationInhibitory reflexAnorectal manometryResting pressureRetrospective reviewBotox injectionHirschsprung's diseaseConstipationEffective treatmentPatientsDysfunction