2020
Evaluation of Fecal Incontinence in Pediatric Functional Constipation
Morera C, Nurko S, Rodriguez L. Evaluation of Fecal Incontinence in Pediatric Functional Constipation. Journal Of Pediatric Gastroenterology And Nutrition 2020, 72: 361-365. PMID: 33560756, DOI: 10.1097/mpg.0000000000002978.Peer-Reviewed Original ResearchConceptsPediatric functional constipationFecal incontinenceFunctional constipationColonic manometryMedian anal resting pressureAnal resting pressureMore patientsResting pressureAbnormal studiesConventional therapyMale genderTreatment outcomesClinical dataConstipationNormal studiesTherapy responseMeal responseIncontinencePatientsMultivariate analysisMotility studiesTherapyNormal armLow responseManometry
2013
Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children
Rodriguez L, Diaz J, Nurko S. Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children. The Journal Of Pediatrics 2013, 163: 261-267. PMID: 23419589, PMCID: PMC3661691, DOI: 10.1016/j.jpeds.2012.12.096.Peer-Reviewed Original ResearchConceptsEfficacy of cyproheptadineDyspeptic symptomsEarly vomitingSide effectsMultivariate analysisRetrospective open-label studyOpen-label studyUpper gastrointestinal symptomsPotent serotonin antagonistUse of cyproheptadineLack of responseLate vomitingAbdominal painGastrointestinal symptomsAntroduodenal manometryFunctional dyspepsiaNissen fundoplicationSerotonin antagonistsFirst therapyGastric emptyingFurther interventionTherapy responseVomitingCyproheptadineResponse rate