2020
Evaluation of Fecal Incontinence in Pediatric Functional Constipation
Morera C, Nurko S, Rodriguez L. Evaluation of Fecal Incontinence in Pediatric Functional Constipation. Journal Of Pediatric Gastroenterology And Nutrition 2020, 72: 361-365. PMID: 33560756, DOI: 10.1097/mpg.0000000000002978.Peer-Reviewed Original ResearchConceptsPediatric functional constipationFecal incontinenceFunctional constipationColonic manometryMedian anal resting pressureAnal resting pressureMore patientsResting pressureAbnormal studiesConventional therapyMale genderTreatment outcomesClinical dataConstipationNormal studiesTherapy responseMeal responseIncontinencePatientsMultivariate analysisMotility studiesTherapyNormal armLow responseManometry
2017
Ileostomy Prolapse in Children with Intestinal Dysmotility
Sparks EA, Velazco CS, Fullerton BS, Fisher JG, Khan FA, Hall AM, Jaksic T, Rodriguez L, Modi BP. Ileostomy Prolapse in Children with Intestinal Dysmotility. Gastroenterology Research And Practice 2017, 2017: 7182429. PMID: 29075290, PMCID: PMC5624168, DOI: 10.1155/2017/7182429.Peer-Reviewed Original ResearchIntestinal dysmotilityIleostomy prolapseStoma prolapseManometric findingsIntestinal manometryTime of ileostomyLog-rank testLogistic regression modelsIntestinal motilityPrimary outcomeRetrospective reviewProlapse rateSingle institutionPrimary diagnosisDysmotilityProlapsePatientsMultivariate analysisClinical diagnosisGreater riskNormal motilityDiagnosisIleostomyManometryUnlikely group
2013
Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children
Rodriguez L, Diaz J, Nurko S. Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children. The Journal Of Pediatrics 2013, 163: 261-267. PMID: 23419589, PMCID: PMC3661691, DOI: 10.1016/j.jpeds.2012.12.096.Peer-Reviewed Original ResearchConceptsEfficacy of cyproheptadineDyspeptic symptomsEarly vomitingSide effectsMultivariate analysisRetrospective open-label studyOpen-label studyUpper gastrointestinal symptomsPotent serotonin antagonistUse of cyproheptadineLack of responseLate vomitingAbdominal painGastrointestinal symptomsAntroduodenal manometryFunctional dyspepsiaNissen fundoplicationSerotonin antagonistsFirst therapyGastric emptyingFurther interventionTherapy responseVomitingCyproheptadineResponse rate
2012
Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility
Rodriguez L, Nurko S, Flores A. Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility. Neurogastroenterology & Motility 2012, 25: 140-e81. PMID: 23035840, PMCID: PMC3546133, DOI: 10.1111/nmo.12018.Peer-Reviewed Original ResearchConceptsAntegrade continence enemaColon manometryACE decreaseContinence enemaColon motilityDefecation disordersOlder ageReview of childrenGastrocolonic responseMotility indexOnly predictorMultivariate analysisDiscontinuationAbstractTextEnemaOutcomesPatientsSignificant increaseChildrenSuccessful decreaseDisordersAgeHAPCsMotilityCM changesClinical Presentation, Response to Therapy, and Outcome of Gastroparesis in Children
Rodriguez L, Irani K, Jiang H, Goldstein AM. Clinical Presentation, Response to Therapy, and Outcome of Gastroparesis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2012, 55: 185-190. PMID: 22228004, DOI: 10.1097/mpg.0b013e318248ed3f.Peer-Reviewed Original ResearchConceptsPediatric gastroparesisPostviral gastroparesisPromotility therapySymptom resolutionClinical featuresMitochondrial dysfunctionYounger ageOutcomes of gastroparesisMore vomitingPromotility drugsAbdominal painClinical presentationMedian timeRetrospective reviewMale sexMean ageEffective therapyGastroparesisVariable symptomatologyMultivariate analysisTherapySymptomsMonthsLonger durationOverall rate