2020
Utility of Colon Manometry in Guiding Therapy and Predicting Need for Surgery in Children With Defecation Disorders
Rodriguez L, Heinz N, Nurko S. Utility of Colon Manometry in Guiding Therapy and Predicting Need for Surgery in Children With Defecation Disorders. Journal Of Pediatric Gastroenterology And Nutrition 2020, 70: 232-237. PMID: 31978023, DOI: 10.1097/mpg.0000000000002504.Peer-Reviewed Original ResearchConceptsColon manometryChange of therapyGastrocolonic responseHigh response rateDefecation disordersResponse rateMedical interventionsLogistic regression analysisPresence/numberPediatric constipationFecal incontinenceSuccessful medical interventionDefecation problemsRetrospective reviewPredicting NeedPostsurgical evaluationSurgical interventionStimulant laxativesStudy indicationSurgeryTherapyFirst interventionInterventionConstipationManometry
2017
Prospective evaluation of same day versus next day colon manometry results in children with medical refractory constipation
Arbizu RA, Nurko S, Heinz N, Amicangelo M, Rodriguez L. Prospective evaluation of same day versus next day colon manometry results in children with medical refractory constipation. Neurogastroenterology & Motility 2017, 29 PMID: 28317231, PMCID: PMC5466533, DOI: 10.1111/nmo.13050.Peer-Reviewed Original ResearchConceptsDay 1Day 2Normal studiesAbnormal studiesProportion of patientsSame dayStudy interpretationColon manometryGastrocolonic responseRefractory constipationProspective evaluationManometry parametersMotility indexPatientsChallenge phaseAbstractTextAnesthesiaCatheterStudy parametersColonoscopyDaysConstipationHAPCsManometryStudy
2012
Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility
Rodriguez L, Nurko S, Flores A. Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility. Neurogastroenterology & Motility 2012, 25: 140-e81. PMID: 23035840, PMCID: PMC3546133, DOI: 10.1111/nmo.12018.Peer-Reviewed Original ResearchConceptsAntegrade continence enemaColon manometryACE decreaseContinence enemaColon motilityDefecation disordersOlder ageReview of childrenGastrocolonic responseMotility indexOnly predictorMultivariate analysisDiscontinuationAbstractTextEnemaOutcomesPatientsSignificant increaseChildrenSuccessful decreaseDisordersAgeHAPCsMotilityCM changes