Hypertension, Blood Pressure Variability, and Acute Kidney Injury in Hospitalized Children
Nugent J, Ghazi L, Yamamoto Y, Bakhoum C, Wilson F, Greenberg J. Hypertension, Blood Pressure Variability, and Acute Kidney Injury in Hospitalized Children. Journal Of The American Heart Association 2023, 12: e029059. PMID: 37119062, PMCID: PMC10227226, DOI: 10.1161/jaha.122.029059.Peer-Reviewed Original ResearchConceptsAcute kidney injuryBlood pressure variabilityBlood pressure measurementsHospitalized childrenKidney injuryBlood pressurePressure variabilityIncident acute kidney injuryTime-updated Cox modelsMean blood pressureEnd-organ complicationsAnalysis of hypertensionAKI riskConclusions HypertensionHypertension thresholdInpatient hypertensionNormotensive patientsOrgan complicationsNonpharmacologic interventionsRetrospective cohortPediatric inpatientsMultivariable modelPediatric encountersHypertensionCox modelDoes This Child With High Blood Pressure Have Secondary Hypertension?
Nugent J, Jiang K, Funaro M, Saran I, Young C, Ghazi L, Bakhoum C, Wilson F, Greenberg J. Does This Child With High Blood Pressure Have Secondary Hypertension? JAMA 2023, 329: 1012-1021. PMID: 36976276, DOI: 10.1001/jama.2023.3184.Peer-Reviewed Original ResearchConceptsBlood pressure loadAmbulatory blood pressure monitoringSecondary hypertensionBlood pressure monitoringPrimary hypertensionFamily historyBlood pressurePressure monitoringDiastolic blood pressure loadSystolic blood pressure loadSerum uric acid concentrationAmbulatory blood pressureHigh blood pressureHistory of prematurityPrimary care clinicsRisk of biasNumber of patientsDatabases of MEDLINEDiagnostic Accuracy Studies toolLower body weightRandom-effects modelingUric acid concentrationWeb of ScienceLikelihood ratioAsymptomatic presentation