2014
Neural plasticity in fathers of human infants
Kim P, Rigo P, Mayes LC, Feldman R, Leckman JF, Swain JE. Neural plasticity in fathers of human infants. Social Neuroscience 2014, 9: 522-535. PMID: 24958358, PMCID: PMC4144350, DOI: 10.1080/17470919.2014.933713.Peer-Reviewed Original ResearchConceptsFathers' brainsNeural plasticityLateral prefrontal cortexCurrent longitudinal studyPosterior cingulate cortexVoxel-based morphometry analysisGray matter volumeNeural basisCognitive developmentNeural regionsNeural changesOrbitofrontal cortexPrefrontal cortexWeeks postpartumHuman fathersParental motivationCingulate cortexHuman infantsMood symptomsBrain regionsLongitudinal studyPostpartum mood symptomsMatter volumeMorphometry analysisHuman mothers
2013
Oxytocin enhances brain function in children with autism
Gordon I, Vander Wyk B, Bennett RH, Cordeaux C, Lucas MV, Eilbott JA, Zagoory-Sharon O, Leckman JF, Feldman R, Pelphrey KA. Oxytocin enhances brain function in children with autism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 20953-20958. PMID: 24297883, PMCID: PMC3876263, DOI: 10.1073/pnas.1312857110.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSuperior temporal sulcusTemporal sulcusOrbitofrontal cortexLeft superior temporal sulcusMiddle frontal gyrusMedial prefrontal cortexRight orbitofrontal cortexSocial attunementSocial judgmentsMeaningful stimuliFrontal gyrusSpectrum disorderBrain activityPrefrontal cortexRight amygdalaSocial functioningFunctional MRIPremotor cortexHedonic evaluationBrain functionJudgmentsCortexChildrenOxytocin
2010
The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum Period
Kim P, Leckman JF, Mayes LC, Feldman R, Wang X, Swain JE. The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum Period. Behavioral Neuroscience 2010, 124: 695-700. PMID: 20939669, PMCID: PMC4318549, DOI: 10.1037/a0020884.Peer-Reviewed Original ResearchConceptsGray matter volumeEarly postpartum periodMatter volumeMaternal brainPostpartum periodParietal lobePrefrontal cortexTime pointsGray matter changesProspective longitudinal studyVoxel-based morphometryMother's brainSubstantia nigraMonths postpartumWeeks postpartumMidbrain areaMatter changesAnimal studiesMaternal motivationBrain regionsLongitudinal changesFirst monthMagnetic resonance imagesHigh-resolution magnetic resonance imagesMaternal behavior
2007
The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
Sukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 2007, 16: 51-59. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderTourette syndromeAbnormal neural oscillationsOscillatory activityHyperactivity disorderAbnormal oscillatory activityThalamo-cortical circuitsSymptoms of ADHDNeural oscillationsNeural oscillatory activityBasal gangliaFunctional abnormalitiesNormal brainThalamocortical regionsThalamocortical oscillationsCortical regionsTransient hyperpolarizationPrefrontal cortexNeural activityNeural communicationPathophysiologyMotor controlSyndromeBrainDisorders
2006
Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations
Leckman JF, Vaccarino FM, Kalanithi PS, Rothenberger A. Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations. Journal Of Child Psychology And Psychiatry 2006, 47: 537-550. PMID: 16712630, DOI: 10.1111/j.1469-7610.2006.01620.x.Peer-Reviewed Original ResearchConceptsTourette syndromeNormal central nervous system functionCentral nervous system functionNeural oscillationsAberrant neural oscillationsSuccessful behavioral treatmentNervous system functionMotor actionsSurgical interventionThalamocortical rhythmsElectrophysiological effectsElectrophysiological findingsSensorimotor gatingSensory urgeSynaptic plasticityTic suppressionAmeliorative effectBehavioral treatmentMotor responsePrefrontal cortexAberrant oscillationsCoherent network activityEffective modulatorPrefrontal regionsRecent evidence