A conceptual framework for the molecular pathogenesis of progressive kidney disease
Schnaper HW, Hubchak SC, Runyan CE, Browne JA, Finer G, Liu X, Hayashida T. A conceptual framework for the molecular pathogenesis of progressive kidney disease. Pediatric Nephrology 2010, 25: 2223-2230. PMID: 20352456, PMCID: PMC5558437, DOI: 10.1007/s00467-010-1503-4.Peer-Reviewed Original ResearchMeSH KeywordsCytokinesDisease ProgressionHumansKidney DiseasesKidney Failure, ChronicKidney GlomerulusModels, BiologicalNephronsProteinuriaConceptsKidney diseaseProgressive nephron lossChronic kidney diseaseProgressive kidney diseaseRole of cytokinesProgressive glomerular diseaseNephron lossGlomerular diseaseClinical conditionsCytokine effectsClinical practiceMolecular pathogenesisDiseasePathogenesisCellular dysfunctionAdaptive physiological responsesPhysiological factorsCellular responsesRepairSubsequent cyclesPhysiological responsesTissue-specific cellular responsesProteinuriaDysfunctionCytokines