Effect of Hydroxyurea on Elevated Pulmonary Artery Pressures in Children with Sickle Cell Disease
Pashankar F, Manwani D, Lee M, Green N. Effect of Hydroxyurea on Elevated Pulmonary Artery Pressures in Children with Sickle Cell Disease. Blood 2011, 118: 4841. DOI: 10.1182/blood.v118.21.4841.4841.Peer-Reviewed Original ResearchTricuspid regurgitant jet velocityElevated pulmonary artery pressurePulmonary artery pressureSickle cell diseaseArtery pressureCell diseaseEffect of hydroxyureaPulmonary hypertensionElevated tricuspid regurgitant jet velocityWhite blood cell countMean reticulocyte countTotal daily doseRegurgitant jet velocityRole of inflammationMean oxygen saturationBlood cell countFetal hemoglobinMean corpuscular volumeRepeat echocardiogramAverage followEndothelial dysfunctionDaily doseEndothelial functionPersistent elevationMean age