Severe Acute Respiratory Syndrome Coronavirus 2 Testing in Children in a Large Regional US Health System During the Coronavirus Disease 2019 Pandemic.
Peaper DR, Murdzek C, Oliveira CR, Murray TS. Severe Acute Respiratory Syndrome Coronavirus 2 Testing in Children in a Large Regional US Health System During the Coronavirus Disease 2019 Pandemic. The Pediatric Infectious Disease Journal 2020, 40: 175-181. PMID: 33399431, PMCID: PMC8852689, DOI: 10.1097/inf.0000000000003024.Peer-Reviewed Original ResearchConceptsYale New Haven Health SystemSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Subset of childrenPediatric casesHealth systemCycle threshold valuesCoronavirus 2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNACross-sectional time-series studyCoronavirus disease 2019 (COVID-19) testingPositive pediatric casesSimilar cycle threshold valuesCoronavirus disease 2019 (COVID-19) pandemicUpper respiratory tractCoronavirus disease 2019Large health systemYears of ageDisease 2019 pandemicUS health systemAmbulatory locationsVirology resultsAsymptomatic childrenSevere Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth
Fernandes DM, Oliveira CR, Guerguis S, Eisenberg R, Choi J, Kim M, Abdelhemid A, Agha R, Agarwal S, Aschner JL, Avner JR, Ballance C, Bock J, Bhavsar SM, Campbell M, Clouser KN, Gesner M, Goldman DL, Hammerschlag MR, Hymes S, Howard A, Jung HJ, Kohlhoff S, Kojaoghlanian T, Lewis R, Nachman S, Naganathan S, Paintsil E, Pall H, Sy S, Wadowski S, Zirinsky E, Cabana MD, Herold BC, Consortium T. Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth. The Journal Of Pediatrics 2020, 230: 23-31.e10. PMID: 33197493, PMCID: PMC7666535, DOI: 10.1016/j.jpeds.2020.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBiomarkersChildChild, PreschoolConnecticutCOVID-19C-Reactive ProteinFemaleHospitalizationHumansHypoxiaInfantIntensive Care UnitsLymphocyte CountMaleMultivariate AnalysisNew JerseyNew YorkPediatric ObesityProcalcitoninProspective StudiesRetrospective StudiesSeverity of Illness IndexSystemic Inflammatory Response SyndromeTroponinYoung AdultConceptsSARS-CoV-2 infectionRespiratory diseaseDisease severityClinical featuresAcute SARS-CoV-2 infectionGreater C-reactive proteinLow absolute lymphocyte countFuture prognostic toolAbsolute lymphocyte countTime of hospitalizationC-reactive proteinIntensive care unitSevere respiratory diseaseNon-Hispanic blacksRace/ethnicitySevere MISInflammatory syndromeLymphocyte countHospital admissionPediatric patientsCare unitMultivariable analysisProspective studyHospitalized childrenClinical management