2016
Biochemical Screening for Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia
Montgomery AM, Bazzy-Asaad A, Asnes JD, Bizzarro MJ, Ehrenkranz RA, Weismann CG. Biochemical Screening for Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia. Neonatology 2016, 109: 190-194. PMID: 26780635, DOI: 10.1159/000442043.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaPulmonary hypertensionGestational ageNT-proBNPBirth weightBiochemical markersPreterm infantsN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptidePresence of PHCross-sectional pilot studyNitric oxideWeeks gestational ageSuch biochemical markersEchocardiographic evidenceScreening echocardiogramsWeeks CGANatriuretic peptideCitrulline levelsInfantsArginine levelsPrecursor citrullineLarger studyEchocardiogramPilot study
2008
Sleep-Disordered Breathing in Children With Metabolic Syndrome: The Role of Leptin and Sympathetic Nervous System Activity and the Effect of Continuous Positive Airway Pressure
Nakra N, Bhargava S, Dzuira J, Caprio S, Bazzy-Asaad A. Sleep-Disordered Breathing in Children With Metabolic Syndrome: The Role of Leptin and Sympathetic Nervous System Activity and the Effect of Continuous Positive Airway Pressure. Pediatrics 2008, 122: e634-e642. PMID: 18762497, PMCID: PMC5117807, DOI: 10.1542/peds.2008-0154.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureSleep-disordered breathingSympathetic nervous system activityPositive airway pressureNervous system activityWhole-body insulin sensitivityMetabolic syndromeAirway pressureLeptin levelsInsulin sensitivitySystem activityExact testContinuous positive airway pressure (CPAP) treatmentPositive airway pressure treatmentC-reactive protein levelsOral glucose tolerance testGlucose tolerance testRole of leptinBMI z-scoreFisher's exact testOvernight polysomnographyBreathing groupMetabolic derangementsInsulin resistanceSleep Questionnaire