Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth
Reddy UM, Page GP, Saade GR, Silver RM, Thorsten VR, Parker CB, Pinar H, Willinger M, Stoll BJ, Heim-Hall J, Varner MW, Goldenberg RL, Bukowski R, Wapner RJ, Drews-Botsch CD, O'Brien BM, Dudley DJ, Levy B. Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth. New England Journal Of Medicine 2012, 367: 2185-2193. PMID: 23215556, PMCID: PMC4295117, DOI: 10.1056/nejmoa1201569.Peer-Reviewed Original ResearchMeSH KeywordsChromosome AberrationsChromosome DisordersChromosomes, HumanGenetic TestingHumansKaryotypingOligonucleotide Array Sequence AnalysisSequence DeletionStillbirthConceptsGenetic abnormalitiesAntepartum stillbirthCongenital anomaliesMicroarray analysisStillbirth Collaborative Research NetworkCopy number variantsAnalysis of stillbirthPopulation-based studyKaryotype analysisResults of karyotypeGeographic catchment areaSingle nucleotide polymorphism arrayClinical significancePostmortem examinationNonviable tissueStillbirthTrue prevalenceFetal tissuesUnaffected personsAbnormalitiesKaryotype resultsMicroarray testingCollaborative research networksGenetic diagnosisPolymorphism array