2020
Association of Prefrontal-Striatal Functional Pathology With Alcohol Abstinence Days at Treatment Initiation and Heavy Drinking After Treatment Initiation
Blaine SK, Wemm S, Fogelman N, Lacadie C, Seo D, Scheinost D, Sinha R. Association of Prefrontal-Striatal Functional Pathology With Alcohol Abstinence Days at Treatment Initiation and Heavy Drinking After Treatment Initiation. American Journal Of Psychiatry 2020, 177: 1048-1059. PMID: 32854534, PMCID: PMC7606814, DOI: 10.1176/appi.ajp.2020.19070703.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTreatment initiationAlcohol abstinenceHeavy drinkingFunctional MRIEarly treatment outcomesEarly treatment phaseHealthy control subjectsEarly outpatient treatmentNumber of daysStress imagesDrinking outcomesChronic alcohol abuseHeavy drinking daysSignificant hyperreactivityControl subjectsOutpatient treatmentStriatal dysfunctionEarly treatmentTreatment outcomesBrain stressFunctional pathologyProspective assessmentTreatment phaseAlcohol abuse
2019
Noninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry
Cao Z, Wemm SE, Han L, Spink DC, Wulfert E. Noninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry. Analytical And Bioanalytical Chemistry 2019, 411: 1203-1210. PMID: 30612174, DOI: 10.1007/s00216-018-1549-x.Peer-Reviewed Original ResearchConceptsLC-MS/MS methodLiquid chromatography-tandem mass spectrometryChromatography-tandem mass spectrometryHuman salivaMeasurement of steroidsPsychoneuroendocrinological researchSalivary DHEADHEACortisolSalivary cortisolSaliva samplesNoninvasive meansCortisol assayYoung adultsSteroidsRegression analysisSalivaMS methodPassive droolNoninvasive determinationHuman cortisolCommon steroidsMales
2018
Stress responding and stress‐related changes in cue reactivity in heavy smokers, problem gamblers, and healthy controls
Wemm SE, Cao Z, Han L, Wulfert E. Stress responding and stress‐related changes in cue reactivity in heavy smokers, problem gamblers, and healthy controls. Addiction Biology 2018, 25: e12687. PMID: 30421575, PMCID: PMC6513727, DOI: 10.1111/adb.12687.Peer-Reviewed Original ResearchConceptsHealthy controlsBlunted cortisol responseMaladaptive stress responsesHigher subjective stressCue-related cravingHeavy smokersStress-related changesControl group responsesSmokersCortisol responseCortisol levelsSubjective stress responsesPsychosocial stressorsSalivary cortisolAcute stressorCue reactivityBehavioral addictionsCravingSubjective cravingSmokingSubstance addictionSubjective responsesCortisolStress responseSubjective stress
2013
Problematic drinking and physiological responses among female college students
Wemm S, Fanean A, Baker A, Blough ER, Mewaldt S, Bardi M. Problematic drinking and physiological responses among female college students. Alcohol 2013, 47: 149-157. PMID: 23333036, DOI: 10.1016/j.alcohol.2012.12.006.Peer-Reviewed Original ResearchConceptsProblematic drinkingLow DHEAS levelsImpaired physiological responseExcessive alcohol useCollege studentsHigher cortisol levelsHigh basal levelsMajority of participantsDHEAS levelsSalivary levelsBinge drinkingAdrenal activityCardiovascular measurementsAlcohol-related consequencesCortisol levelsBehavioral stress responsesAlcohol dependenceSelf-reported consequencesSelf-reported drinkingSaliva samplesAlcohol useBasal levelsFemale college studentsDistress tolerancePhysiological responses
2010
The role of DHEA in relation to problem solving and academic performance
Wemm S, Koone T, Blough ER, Mewaldt S, Bardi M. The role of DHEA in relation to problem solving and academic performance. Biological Psychology 2010, 85: 53-61. PMID: 20562010, DOI: 10.1016/j.biopsycho.2010.05.003.Peer-Reviewed Original ResearchConceptsGrade point averageAmerican College Testing (ACT) scoresCurrent grade point averageSets of anagramsTask demandsBehavioral tasksBehavioral flexibilityAcademic achievementMood disturbanceAcademic performanceProblem solvingCollege studentsPhysiological neuroprotectionPoint averageBehavioral responsesTaskTesting scoresCollege coursesParticipantsIndividualsAnagramsSame individualAnxietyChallenging taskHigh levels