Stephanie O'Malley, PhD

Elizabeth Mears and House Jameson Professor of Psychiatry

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Appointments

Psychiatry

Primary

Additional Titles

Deputy Chair, Clinical Research

Contact Info

stephanie.omalley@yale.edu

Psychiatry

Connecticut Mental Health Center - SAC 202, 34 Park Street

New Haven, CT 06508

United States

About

Titles

Elizabeth Mears and House Jameson Professor of Psychiatry

Deputy Chair, Clinical Research

Appointments

Psychiatry
Professor
Primary
Psychiatry

ADVANCE Study
Cancer Prevention and Control
Center for Nicotine and Tobacco Use Research at Yale (CENTURY)
Center for the Translational Neuroscience of Alcohol
Connecticut Mental Health Center
Division of Addictions
Division of Substance Abuse
Division of Women's Behavioral Health Research
Neuroscience Research Training Program (NRTP)
Psychiatry
Psychology Section
Psychotherapy Development Center
Smoking Cessation and Alcohol Treatment Research Clinic
Stress & Addiction Clinical Research Program
Substance Abuse Research
Tobacco Research in Youth (TRY)
Yale Cancer Center
Yale Medicine
Yale Tobacco Center of Regulatory Science
Yale Ventures

Education & Training

PhD: Vanderbilt University (1983)

BS: Vanderbilt University (1976)

Research

Overview

Yale Tobacco Center for Regulatory Science

Clinical trials of varenicline for the treatment of alcohol dependence among smokers and of naltrexone for young adult heavy drinkers

Laboratory studies to evaluate medications for substance use disorders

Validation of biomarkers for monitoring drinking in clinical trials

Secondary analyses to identify moderators and predictors of response to treatments for alcohol dependence using tree based and trajectory analyses

Training of clinician and transdisciplinary scientists

Medical Research Interests

Alcoholism; Psychiatry; Psychiatry and Psychology; Risk Reduction Behavior; Smoking; Substance-Related Disorders

ORCID
0000-0002-1976-2369

Research at a Glance

Yale Co-Authors

Frequent collaborators of Stephanie O'Malley's published research.

Suchitra Krishnan-Sarin, PhD
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View 10 Common Publications
Krysten Bold, PhD
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View 6 Common Publications
Lisa Fucito, PhD
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View 6 Common Publications
Meghan Morean, PhD
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View 6 Common Publications
Ralitza Gueorguieva, PhD
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View 6 Common Publications
Kelly S. DeMartini, PhD
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View 4 Common Publications

Publications

2026

From cool to non-cool: California’s ‘non-menthol’ cigarettes in 2025
Jabba S, Erythropel H, Anastas P, O’Malley S, Krishnan-Sarin S, Zimmerman J, Jordt S. From cool to non-cool: California’s ‘non-menthol’ cigarettes in 2025. Tobacco Prevention & Cessation 2026, 12: 1-5. PMID: 42211562, PMCID: PMC13215131, DOI: 10.18332/tpc/217322.
Peer-Reviewed Original Research
Water addition to e-liquids to reduce flavour aldehyde acetal formation: chemistry and user sensory experience and appeal
Davis D, Green B, Krishnan-Sarin S, Martin T, Wu R, Gueorguieva R, Anastas P, Zimmerman J, O’Malley S, Allen W, Erythropel H. Water addition to e-liquids to reduce flavour aldehyde acetal formation: chemistry and user sensory experience and appeal. Tobacco Control 2026, tc-2025-060013. PMID: 42161504, PMCID: PMC13330406, DOI: 10.1136/tc-2025-060013.
Peer-Reviewed Original Research

2025

Oura Ring Behavioral Feedback Intervention for Alcohol Reduction in Young Adults: User Experience Evaluation of a Pilot Randomized Trial
Griffith F, Ellison O, Kunchay S, Augustine M, DeMartini K, Fatigate M, Latimer L, O'Malley S, Redeker N, Ash G, Fucito L. Oura Ring Behavioral Feedback Intervention for Alcohol Reduction in Young Adults: User Experience Evaluation of a Pilot Randomized Trial. Journal Of Medical Internet Research 2025, 27: e78613. PMID: 41343856, PMCID: PMC12677873, DOI: 10.2196/78613.
Peer-Reviewed Original Research
MeSH Keywords
Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials
Witkiewitz K, Anton R, O’Malley S, Hasin D, Silverman B, Aldridge A, Mann K, Kranzler H, Aubin H, Hoffman M, Wong C, Meulien D, Zarkin G. Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials. JAMA Psychiatry 2025, 82: 1246-1254. PMID: 40960803, PMCID: PMC12739655, DOI: 10.1001/jamapsychiatry.2025.2508.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
New Reduced Drinking Goals in Alcohol Pharmacotherapy Trials—A Novel Public-Private Effort and FDA Approval Process
Anton R, O’Malley S, Mann K, Silverman B. New Reduced Drinking Goals in Alcohol Pharmacotherapy Trials—A Novel Public-Private Effort and FDA Approval Process. JAMA Psychiatry 2025, 82: 1159-1160. PMID: 40960805, DOI: 10.1001/jamapsychiatry.2025.2515.
Peer-Reviewed Original Research
Feasibility and efficacy of a real-time smoking intervention using wearable technology
Bold K, Mestre L, Garrison K, Gueorguieva R, O'Malley S, Fucito L. Feasibility and efficacy of a real-time smoking intervention using wearable technology. PLOS Digital Health 2025, 4: e0001086. PMID: 41212887, PMCID: PMC12599971, DOI: 10.1371/journal.pdig.0001086.
Peer-Reviewed Original Research
Trends in Newly Filled GLP-1 Receptor Agonist Prescriptions for U.S. Patients With Versus Without Comorbid Alcohol Use Disorder, 2016 to 2024
Wallach J, O’Malley S, Lipska K, Ross J, Jeffery M, Savitz S. Trends in Newly Filled GLP-1 Receptor Agonist Prescriptions for U.S. Patients With Versus Without Comorbid Alcohol Use Disorder, 2016 to 2024. Journal Of Addiction Medicine 2025, 10.1097/adm.0000000000001575. PMID: 41036780, PMCID: PMC12636227, DOI: 10.1097/adm.0000000000001575.
Peer-Reviewed Original Research
The alcohol cue‐exposure paradigm as a screening tool for alcohol use disorder medication development: A critical review
Kirsch D, Grodin E, Leggio L, McKee S, Meredith L, Mereish E, Miranda R, Nieto S, O'Malley S, Schacht J, Ray L. The alcohol cue‐exposure paradigm as a screening tool for alcohol use disorder medication development: A critical review. Alcohol Clinical And Experimental Research 2025, 49: 2412-2426. PMID: 41017297, PMCID: PMC12638288, DOI: 10.1111/acer.70170.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Who is alcohol cue-reactive? A machine learning approach
Kirsch D, McManus K, Grodin E, Nieto S, Miranda R, O’Malley S, Schacht J, Ray L. Who is alcohol cue-reactive? A machine learning approach. Alcohol And Alcoholism 2025, 60: agaf052. PMID: 40838757, PMCID: PMC12368849, DOI: 10.1093/alcalc/agaf052.
Peer-Reviewed Original Research
MeSH Keywords
A Randomized Trial of Alcohol Telemedicine in Primary Care: Pharmacotherapy and Referral Outcomes
Sterling S, Leibowitz A, Satre D, Cocohoba J, Kline-Simon A, Weisner C, Metz V, Ghadiali M, Corriveau C, O’Malley S, Awsare S, Morris M, Parthasarathy S. A Randomized Trial of Alcohol Telemedicine in Primary Care: Pharmacotherapy and Referral Outcomes. Journal Of General Internal Medicine 2025, 41: 6-15. PMID: 40634649, PMCID: PMC12855671, DOI: 10.1007/s11606-025-09708-y.
Peer-Reviewed Original Research

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Clinical Trials

Current Trials

Brief training for 18-26 year olds: Regulation of alcohol craving
IRB ID2000029394RoleSub InvestigatorPrimary Completion Date12/31/2022
Recruiting ParticipantsGenderBothAge18 years - 26 years
Addiction

Academic Achievements & Community Involvement

Activities

activity
Alcoholism:Clinical and Experimental Research
2011 - PresentProfessional OrganizationsMember
Details
activity
American College of Neuropsychopharmacology/American Society of Clinical Psychopharmacology
2008 - PresentProfessional OrganizationsMember
Details
activity
Psychiatry Investigation
2004 - PresentProfessional OrganizationsMember
Details
activity
JAMA Psychiatry
2015 - PresentProfessional OrganizationsMember
Details
activity
NIDA
2015 - PresentCommitteesMember
Details

View full list of activities

Honors

honor
Thwarp Award
11/01/2018National AwardFirst Tennessee Bank, Trustee under Will of James H. Thwarp
Details
honor
Distinguished Researcher Award
06/15/2018National AwardResearch Society on Alcoholism
Details
honor
Sidney J. Blatt Award
06/01/2015Yale School of Medicine AwardPsychology Section, Department of Psychiatry
Details
honor
Elected Member
04/01/2014Regional AwardConnecticut Academy of Science and Engineering (CASE)
Details
honor
Presidential Citation for Leadership and Research in the Field of Addictions
04/01/2014National AwardAmerican Psychological Association
Details

View full list of honors

News & Links

News

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Related Links
- Center for Tobacco and Nicotine Use Research at Yale
- YouTube, What It Means To Discover: A Researcher's Perspective

Get In Touch

Contacts

stephanie.omalley@yale.edu

Mailing Address

Psychiatry

Connecticut Mental Health Center - SAC 202, 34 Park Street

New Haven, CT 06508

United States

Appointments

Additional Titles

Contact Info

Titles

Appointments

Psychiatry

Other Departments & Organizations

Education & Training

Overview

Medical Research Interests

ORCID

Research at a Glance

Yale Co-Authors

Suchitra Krishnan-Sarin, PhD

Krysten Bold, PhD

Lisa Fucito, PhD

Meghan Morean, PhD

Ralitza Gueorguieva, PhD

Kelly S. DeMartini, PhD

Publications

2026

2025

Clinical Trials

Current Trials

Activities

Alcoholism:Clinical and Experimental Research

American College of Neuropsychopharmacology/American Society of Clinical Psychopharmacology

Psychiatry Investigation

JAMA Psychiatry

NIDA

Honors

Thwarp Award

Distinguished Researcher Award

Sidney J. Blatt Award

Elected Member

Presidential Citation for Leadership and Research in the Field of Addictions

News

A More Personalized Approach to Alcohol Treatment

Center for the Translational Neuroscience of Alcohol Receives NIAAA Funding to Continue Research

Crouch, Cook, O'Malley Establish Research, Training, Clinical Care Partnership in Alaska

For Young Adults, Improved Sleep Is Incentive to Drink Less

Related Links

Contacts