2019
Optoacoustic Imaging and Gray-Scale US Features of Breast Cancers: Correlation with Molecular Subtypes.
Dogan BE, Menezes GLG, Butler RS, Neuschler EI, Aitchison R, Lavin PT, Tucker FL, Grobmyer SR, Otto PM, Stavros AT. Optoacoustic Imaging and Gray-Scale US Features of Breast Cancers: Correlation with Molecular Subtypes. Radiology 2019, 292: 564-572. PMID: 31287388, DOI: 10.1148/radiol.2019182071.Peer-Reviewed Original ResearchConceptsBreast cancer molecular subtypesHuman epidermal growth factor receptorLuminal breast cancerCancer molecular subtypesUS featuresEpidermal growth factor receptorMolecular subtypesGrowth factor receptorBreast cancerProspective multi-institutional studyFactor receptorLogistic regression analysisMulti-institutional studyLogistic regression modelsMultinomial logistic regression analysisGray-scale USMultinomial logistic regression modelsImmunohistochemistry findingsMean ageInvasive cancerPathologic diagnosisPathology reportsUS scoreKruskal-Wallis testCancer subtypes
2017
A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists
Neuschler EI, Butler R, Young CA, Barke LD, Bertrand ML, Böhm-Vélez M, Destounis S, Donlan P, Grobmyer SR, Katzen J, Kist KA, Lavin PT, Makariou EV, Parris TM, Schilling KJ, Tucker FL, Dogan BE. A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists. Radiology 2017, 287: 172228. PMID: 29178816, DOI: 10.1148/radiol.2017172228.Peer-Reviewed Original ResearchConceptsProbability of malignancyNegative likelihood ratioGrayscale ultrasonographyIndependent readersMalignant breast massesBreast massesBlinded independent readersMalignant massesBI-RADS 3Negative predictive valueData System (BI-RADS) categoryBreast Imaging ReportingBI-RADS categoryLikelihood ratioOA featuresHistologic findingsBI-RADS categoriesNegative examinationsPretest probabilityProtocol deviationsHistologic resultsOnline supplemental materialUltrasonographyDiagnostic utilityPredictive value
2016
Tomosynthesis in the Diagnostic Setting: Changing Rates of BI-RADS Final Assessment over Time.
Raghu M, Durand MA, Andrejeva L, Goehler A, Michalski MH, Geisel JL, Hooley RJ, Horvath LJ, Butler R, Forman HP, Philpotts LE. Tomosynthesis in the Diagnostic Setting: Changing Rates of BI-RADS Final Assessment over Time. Radiology 2016, 281: 54-61. PMID: 27139264, DOI: 10.1148/radiol.2016151999.Peer-Reviewed Original Research
2012
Screening US in Patients with Mammographically Dense Breasts: Initial Experience with Connecticut Public Act 09-41
Hooley RJ, Greenberg KL, Stackhouse RM, Geisel JL, Butler RS, Philpotts LE. Screening US in Patients with Mammographically Dense Breasts: Initial Experience with Connecticut Public Act 09-41. Radiology 2012, 265: 59-69. PMID: 22723501, DOI: 10.1148/radiol.12120621.Peer-Reviewed Original ResearchConceptsPositive predictive valueOverall positive predictive valueBI-RADS category 4BI-RADS category 3Breast ultrasonographyDense breastsBreast cancerOverall cancer detection rateHIPAA-compliant retrospective reviewData System (BI-RADS) category 1Occult breast cancerCancer detection rateWhole-breast ultrasonographyCategory 4Category 3Dense breast tissueBreast Imaging ReportingPostmenopausal patientsIntermediate riskRetrospective reviewRisk groupsUS examinationHigh riskGeneral populationLower risk