2019
Optoacoustic Imaging and Gray-Scale US Features of Breast Cancers: Correlation with Molecular Subtypes.
Dogan BE, Menezes GLG, Butler RS, Neuschler EI, Aitchison R, Lavin PT, Tucker FL, Grobmyer SR, Otto PM, Stavros AT. Optoacoustic Imaging and Gray-Scale US Features of Breast Cancers: Correlation with Molecular Subtypes. Radiology 2019, 292: 564-572. PMID: 31287388, DOI: 10.1148/radiol.2019182071.Peer-Reviewed Original ResearchConceptsBreast cancer molecular subtypesHuman epidermal growth factor receptorLuminal breast cancerCancer molecular subtypesUS featuresEpidermal growth factor receptorMolecular subtypesGrowth factor receptorBreast cancerProspective multi-institutional studyFactor receptorLogistic regression analysisMulti-institutional studyLogistic regression modelsMultinomial logistic regression analysisGray-scale USMultinomial logistic regression modelsImmunohistochemistry findingsMean ageInvasive cancerPathologic diagnosisPathology reportsUS scoreKruskal-Wallis testCancer subtypes
2017
A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists
Neuschler EI, Butler R, Young CA, Barke LD, Bertrand ML, Böhm-Vélez M, Destounis S, Donlan P, Grobmyer SR, Katzen J, Kist KA, Lavin PT, Makariou EV, Parris TM, Schilling KJ, Tucker FL, Dogan BE. A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists. Radiology 2017, 287: 172228. PMID: 29178816, DOI: 10.1148/radiol.2017172228.Peer-Reviewed Original ResearchConceptsProbability of malignancyNegative likelihood ratioGrayscale ultrasonographyIndependent readersMalignant breast massesBreast massesBlinded independent readersMalignant massesBI-RADS 3Negative predictive valueData System (BI-RADS) categoryBreast Imaging ReportingBI-RADS categoryLikelihood ratioOA featuresHistologic findingsBI-RADS categoriesNegative examinationsPretest probabilityProtocol deviationsHistologic resultsOnline supplemental materialUltrasonographyDiagnostic utilityPredictive value