2016
Dynamic neural activity during stress signals resilient coping
Sinha R, Lacadie CM, Constable RT, Seo D. Dynamic neural activity during stress signals resilient coping. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 8837-8842. PMID: 27432990, PMCID: PMC4978278, DOI: 10.1073/pnas.1600965113.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexVentrolateral prefrontal cortexResilient copingNeural activationPrefrontal cortexFunctional magnetic resonance imaging studyDorsolateral prefrontal cortex regionsNeutral visual stimuliVentromedial prefrontal cortexHealthy stress responseDynamic neural activityPrefrontal cortex regionsAnterior cingulate cortexFrequency of argumentsMagnetic resonance imaging studyResonance imaging studyVmPFC activationEmotional eatingNeural processesStress processingVisual stimuliViolent stimuliBinge alcohol intakeBrain networksRight insula
2013
Disrupted Ventromedial Prefrontal Function, Alcohol Craving, and Subsequent Relapse Risk
Seo D, Lacadie CM, Tuit K, Hong KI, Constable RT, Sinha R. Disrupted Ventromedial Prefrontal Function, Alcohol Craving, and Subsequent Relapse Risk. JAMA Psychiatry 2013, 70: 727-739. PMID: 23636842, PMCID: PMC3788824, DOI: 10.1001/jamapsychiatry.2013.762.Peer-Reviewed Original ResearchConceptsHealthy control subjectsAD patientsControl subjectsInpatient treatmentAlcohol cravingAlcohol cuesBrain responsesRelapse riskAlcohol relapseHospital-based research unitAnterior cingulate cortex activationAlcohol-related cuesCommunity mental health centerVentromedial prefrontal functionChronic relapsing illnessVentromedial prefrontal cortexStress-induced cravingAbstinent alcohol-dependent patientsFunctional magnetic resonanceMental health centersAlcohol-dependent patientsSubsequent relapse riskNeural correlatesNeutral trialsHazard ratio