2023
Therapeutics for Substance-Using Women: The Need to Elucidate Sex-Specific Targets for Better-Tailored Treatments
Fox H, Milivojevic V, Sinha R. Therapeutics for Substance-Using Women: The Need to Elucidate Sex-Specific Targets for Better-Tailored Treatments. Handbook Of Experimental Pharmacology 2023, 282: 127-161. PMID: 37592081, DOI: 10.1007/164_2023_687.Peer-Reviewed Original ResearchConceptsSubstance-using womenExogenous progesteroneBetter tailor treatmentsStress-induced cravingFace of stressSex-specific targetsGender-related differencesAdrenergic medicationsStress-related adaptationClinical trialsSpecific treatmentMedication developmentAlcohol consumptionCompulsive drugBiobehavioral mechanismsDrinking historyMedical problemsInnovative medicationsMedicationsNovel targetWomenGuanfacineProgesteroneTreatmentEfficacy
2018
Central and Peripheral Biomarkers of Stress Response for Addiction Risk and Relapse Vulnerability
Milivojevic V, Sinha R. Central and Peripheral Biomarkers of Stress Response for Addiction Risk and Relapse Vulnerability. Trends In Molecular Medicine 2018, 24: 173-186. PMID: 29396148, PMCID: PMC6511993, DOI: 10.1016/j.molmed.2017.12.010.Peer-Reviewed Original ResearchConceptsSubstance use disordersTreatment of SUDsDevelopment of SUDHigh relapse rateFunctional brain alterationsCentral stress responseAdrenal axis markersStress response measuresRelapse ratePeripheral biomarkersClinical symptomatologyBrain alterationsUse disordersCandidate biomarkersAutonomic responsesRelapse vulnerabilityPutative biomarkersAddiction riskStress responseBiomarkersTreatmentResponsePathophysiologySymptomatologyPrevention
2007
Connecticut Mental Health Center: Clinical, Research and Training Programs in the Addictions
Schottenfeld R, Carroll K, Kosten T, O'Malley S, Rounsaville B, Sinha R, Kleber H. Connecticut Mental Health Center: Clinical, Research and Training Programs in the Addictions. 2007, 21-49. DOI: 10.1002/9780470994580.ch2.Peer-Reviewed Original Research
2005
96 Alcohol Abuse and Eating Disorders
Schwartz M, Sinha R. 96 Alcohol Abuse and Eating Disorders. 2005, 1263-1275. DOI: 10.1016/b978-012564370-2/50098-2.Peer-Reviewed Original ResearchAlcohol abusePossible etiological factorsClinical treatment researchRelevant control groupsEtiological factorsTreatment approachesControl groupBulimia nervosaAnorexia nervosaClinical settingPatientsSignificant subgroupEating DisordersDisordersOverall rateTreatment researchCommunity sampleTreatmentNervosaAbuseEDPrevalence
2000
Alcohol and Eating Disorders: Implications for Alcohol Treatment and Health Services Research
Sinha R, O'Malley S. Alcohol and Eating Disorders: Implications for Alcohol Treatment and Health Services Research. Alcohol Clinical And Experimental Research 2000, 24: 1312-1319. PMID: 10968671, DOI: 10.1111/j.1530-0277.2000.tb02097.x.Peer-Reviewed Original ResearchConceptsHealth services research perspectivePossible etiologic associationAlcohol use disorderHealth services researchClinical manifestationsEtiologic associationAlcoholic womenPsychiatric disordersUse disordersAlcohol treatmentClinical implicationsBehavioral treatmentDisordersTreatment implicationsEating DisordersAlcoholismComorbiditiesWomenHigh rateServices researchSubstantial evidenceExpected ratesTreatmentReview
1998
Can line clinicians master the conceptual complexities of dialectical behavior therapy? An evaluation of a State Department of Mental Health training program
Hawkins K, Sinha R. Can line clinicians master the conceptual complexities of dialectical behavior therapy? An evaluation of a State Department of Mental Health training program. Journal Of Psychiatric Research 1998, 32: 379-384. PMID: 9844954, DOI: 10.1016/s0022-3956(98)00030-2.Peer-Reviewed Original ResearchConceptsDialectical behavior therapyBehavior therapyMental health training programBorderline personality disorderHealth training programsMental health initiativesEfficacy dataClinical utilityDBT trainingHealth initiativesCliniciansNumerous cliniciansMental healthTherapyPersonality disorderEase of disseminationMarsha LinehanTreatmentDiverse rolesMultifaceted approachDepartmentTraining programTreatment theoryExamination
1993
Simple Reaction Time Event‐Related Potentials: Effects of Alcohol and Sleep Deprivation
Krull K, Smith L, Sinha R, Parsons O. Simple Reaction Time Event‐Related Potentials: Effects of Alcohol and Sleep Deprivation. Alcohol Clinical And Experimental Research 1993, 17: 771-777. PMID: 8214412, DOI: 10.1111/j.1530-0277.1993.tb00839.x.Peer-Reviewed Original ResearchConceptsBreath alcohol concentrationSleep deprivationNormal male subjectsEvent-related potentialsLatency of N2Effects of alcoholVisual event-related potentialsMale subjectsAlcohol intoxicationSimple reaction timeResponse activationStimulus detectionDeprivationAlcohol concentrationNegative componentTreatmentAdditive increase