2017
MULTIPLE BIOMARKERS FOR PREDICTING MAJOR ADVERSE CARDIAC EVENTS IN AT-RISK PATIENTS UNDERGOING DIAGNOSTIC CORONARY ANGIOGRAPHY: RESULTS FROM THE CATHETER SAMPLED BLOOD ARCHIVE IN CARDIOVASCULAR DISEASES (CASABLANCA) STUDY
McCarthy C, Van Kimmenade R, Gaggin H, Simon M, Ibrahim N, Gandhi P, Kelly N, Belcher A, Motiwala S, Rhyne R, Magaret C, Januzzi J. MULTIPLE BIOMARKERS FOR PREDICTING MAJOR ADVERSE CARDIAC EVENTS IN AT-RISK PATIENTS UNDERGOING DIAGNOSTIC CORONARY ANGIOGRAPHY: RESULTS FROM THE CATHETER SAMPLED BLOOD ARCHIVE IN CARDIOVASCULAR DISEASES (CASABLANCA) STUDY. Journal Of The American College Of Cardiology 2017, 69: 78. DOI: 10.1016/s0735-1097(17)33467-8.Peer-Reviewed Original Research
2016
Prognostic Value of Insulin-Like Growth Factor-Binding Protein 7 in Patients with Heart Failure and Preserved Ejection Fraction
Gandhi PU, Chow SL, Rector TS, Krum H, Gaggin HK, McMurray JJ, Zile MR, Komajda M, McKelvie RS, Carson PE, Januzzi JL, Anand IS. Prognostic Value of Insulin-Like Growth Factor-Binding Protein 7 in Patients with Heart Failure and Preserved Ejection Fraction. Journal Of Cardiac Failure 2016, 23: 20-28. PMID: 27317843, DOI: 10.1016/j.cardfail.2016.06.006.Peer-Reviewed Original ResearchConceptsInsulin-like growth factor-binding protein 7Heart failureCause mortalityPrimary outcomeEjection fractionHF eventsInsulin-like growth factorEjection Fraction trialGlomerular filtration rateSigns/symptomsProtein 7Binding protein 7Cardiovascular eventsMultivariable adjustmentSecondary outcomesCardiovascular hospitalizationPrognostic valueFiltration ratePrognostic meritTreatment groupsGrowth factorOutcomesFurther studiesPatientsEGFRASSESSMENT OF SERIAL HEART RATE AND BETA BLOCKER USE IN A CONTEMPORARY CHRONIC SYSTOLIC HEART FAILURE PATIENTS: RESULTS FROM THE PROBNP OUTPATIENT TAILORED CHRONIC HEART FAILURE (PROTECT) STUDY
Gaggin H, Rabideau D, Ibrahim N, Gandhi P, Januzzi J. ASSESSMENT OF SERIAL HEART RATE AND BETA BLOCKER USE IN A CONTEMPORARY CHRONIC SYSTOLIC HEART FAILURE PATIENTS: RESULTS FROM THE PROBNP OUTPATIENT TAILORED CHRONIC HEART FAILURE (PROTECT) STUDY. Journal Of The American College Of Cardiology 2016, 67: 1316. DOI: 10.1016/s0735-1097(16)31317-1.Peer-Reviewed Original Research
2015
Natriuretic Peptides for Diagnosis, Prognosis, and Management of Heart Failure
Gandhi P, Januzzi Jr. J. Natriuretic Peptides for Diagnosis, Prognosis, and Management of Heart Failure. Biomarkers In Disease: Methods, Discoveries And Applications 2015, 731-756. DOI: 10.1007/978-94-007-7696-8_12.ChaptersB-type natriuretic peptideHeart failureNatriuretic peptideEjection fractionAmino-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideHeart failure screeningReduced ejection fractionNatriuretic peptide releaseUse of biomarkersComplicated patientsRoutine carePressure overloadClinical assessmentMyocyte stretchCardiovascular homeostasisFluid balanceCardiac conditionsComplex syndromePatientsPersonalized carePeptide releaseMultiple studiesMillions of peopleCareAnalysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure
Gandhi PU, Gaggin HK, Belcher AM, Harisiades JE, Basile A, Falco A, Rosati A, Piscione F, Januzzi JL, Turco MC. Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure. Clinica Chimica Acta 2015, 445: 73-78. PMID: 25753466, DOI: 10.1016/j.cca.2015.02.048.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdaptor Proteins, Signal TransducingAdrenomedullinAgedAged, 80 and overApoptosis Regulatory ProteinsAtrial Natriuretic FactorBiomarkersErbB ReceptorsFemaleGene ExpressionHeart FailureHeart VentriclesHumansInterleukin-1 Receptor-Like 1 ProteinKidney Function TestsMalePrognosisReceptors, Cell SurfaceStroke VolumeSurvival AnalysisConceptsLeft ventricular ejection fractionBcl-2-associated athanogene 3Heart failureNatriuretic peptidePlasma concentrationsCox proportional hazards regressionWorse renal functionVentricular ejection fractionKaplan-Meier analysisProportional hazards regressionSignificant mortality predictorsCox proportional hazardsGenesis of cardiomyopathyHF prognosisHF patientsBaseline characteristicsPrimary endpointRenal functionEjection fractionHazards regressionMortality predictorsVital statusPrognostic valuePatientsProportional hazards
2014
THE CLINICAL IMPACT OF ATRIAL FIBRILLATION IN PATIENTS WITH THE HEARTMATE II LEFT VENTRICULAR ASSIST DEVICE
Enriquez A, Calenda B, Gandhi P, Nair A, Anyanwu A, Pinney S. THE CLINICAL IMPACT OF ATRIAL FIBRILLATION IN PATIENTS WITH THE HEARTMATE II LEFT VENTRICULAR ASSIST DEVICE. Journal Of The American College Of Cardiology 2014, 63: a888. DOI: 10.1016/s0735-1097(14)60888-3.Peer-Reviewed Original ResearchINSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 IN HEART FAILURE PATIENTS: A NOVEL BIOMARKER OF MYOCARDIAL DIASTOLIC FUNCTION?
Gandhi P, Motiwala S, Sheftel A, Weiner R, Baggish A, Gaggin H, Liu P, Januzzi J. INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 IN HEART FAILURE PATIENTS: A NOVEL BIOMARKER OF MYOCARDIAL DIASTOLIC FUNCTION? Journal Of The American College Of Cardiology 2014, 63: a788. DOI: 10.1016/s0735-1097(14)60788-9.Peer-Reviewed Original ResearchNatriuretic Peptides for Diagnosis, Prognosis, and Management of Heart Failure
Gandhi P, Januzzi Jr. J. Natriuretic Peptides for Diagnosis, Prognosis, and Management of Heart Failure. 2014, 1-21. DOI: 10.1007/978-94-007-7740-8_12-1.ChaptersB-type natriuretic peptideHeart failureNatriuretic peptideEjection fractionAmino-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideHeart failure screeningReduced ejection fractionNatriuretic peptide releaseUse of biomarkersComplicated patientsRoutine carePressure overloadClinical assessmentMyocyte stretchCardiovascular homeostasisFluid balanceCardiac conditionsComplex syndromePatientsPersonalized carePeptide releaseMultiple studiesMillions of peopleCare