2020
Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst
Shallis RM, Weiss JJ, Deziel NC, Gore SD. Challenging the concept of de novo acute myeloid leukemia: Environmental and occupational leukemogens hiding in our midst. Blood Reviews 2020, 47: 100760. PMID: 32988660, DOI: 10.1016/j.blre.2020.100760.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaDe novo acute myeloid leukemiaNovo acute myeloid leukemiaMyeloid leukemiaRisk of AMLTherapy-related acute myeloid leukemiaParticular chemotherapeutic agentsOccupational exposureIndividual patientsMyeloid neoplasmsGermline predispositionAccidental exposureLeukemogenChemotherapeutic agentsMarrow microenvironmentLeukemiaEnvironmental agentsAcceptable exposure limitsCell acquisitionPatientsExposure limitsExposureInescapable exposureAmbient exposureRisk
2018
Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber
Perkins AN, Inayat-Hussain SH, Deziel NC, Johnson CH, Ferguson SS, Garcia-Milian R, Thompson DC, Vasiliou V. Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber. Environmental Research 2018, 169: 163-172. PMID: 30458352, PMCID: PMC6396308, DOI: 10.1016/j.envres.2018.10.018.Peer-Reviewed Original ResearchMeSH KeywordsCarcinogensElastomersEnvironmental ExposureEuropeHumansOrganic ChemicalsRubberUnited StatesConceptsSynthetic turf fieldsCrumb rubber infillEuropean Chemicals AgencyOrganic chemicalsUS EPAADMET PredictorRubber infillUnited States Environmental Protection AgencyFuture exposure studiesChemical constituentsStates Environmental Protection AgencyHazardous chemicalsComputational toxicologyChemical componentsVinyl chlorideChemicalsPriority carcinogensTurf fieldsToxicology assessmentEnvironmental Protection AgencyCarcinogenic chemicalsChemicals AgencyExposure studiesECHA databasePotential carcinogenicity
2012
Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP)
Deziel NC, Buckley TJ, Sinha R, Abubaker S, Platz EA, Strickland PT. Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP). Food Additives & Contaminants Part A 2012, 29: 1202-1211. PMID: 22571725, PMCID: PMC3412362, DOI: 10.1080/19440049.2012.682657.Peer-Reviewed Original ResearchConceptsIntraclass correlation coefficientPhIP intakeUrinary PhIPDietary Heterocyclic Amine ExposureHeterocyclic amine exposureFull study populationSubject variabilityExposure assessment methodsBiomarker-based approachDiary-based estimatesSpearman correlation coefficientDietary intakeStudy populationEpidemiologic studiesLong-term exposureHCA 2Intake estimatesAmine exposurePhIP concentrationIntakePhIPInconsistent riskTerm exposureAssessment toolDiary collection