2023
Precipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report
Christian N, Butner J, Evarts M, Weimer M. Precipitated Opioid Withdrawal Treated With Ketamine in a Hospitalized Patient: A Case Report. Journal Of Addiction Medicine 2023, 17: 488-490. PMID: 37579118, DOI: 10.1097/adm.0000000000001151.Peer-Reviewed Case Reports and Technical NotesConceptsClinical Opiate Withdrawal Scale (COWS) scoresOpioid use disorderKetamine infusionOpioid withdrawalCase reportUse disordersScale scoreSevere opioid use disorderFull opioid agonistsHours of admissionEmergency department settingFirst case reportInpatient hospital settingLife-saving medicationsReceptor-mediated signalingLack of evidenceMale patientsFentanyl useOpioid agonistsEmergency departmentComplete resolutionDepartment settingClinical dilemmaAppropriate treatmentHospital setting
2022
Perioperative Buprenorphine Management A Multidisciplinary Approach
Hickey T, Abelleira A, Acampora G, Becker WC, Falker CG, Nazario M, Weimer MB. Perioperative Buprenorphine Management A Multidisciplinary Approach. Medical Clinics Of North America 2022, 106: 169-185. PMID: 34823729, DOI: 10.1016/j.mcna.2021.09.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAcetaminophenAgedAnalgesics, Non-NarcoticAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalArthroplasty, Replacement, HipBuprenorphineCombined Modality TherapyDrug CompoundingFemaleHumansInterdisciplinary CommunicationMaleOpiate Substitution TreatmentOpioid-Related DisordersPainPain ManagementPain, PostoperativePerioperative CareReceptors, Opioid, muConceptsOpioid use disorderBuprenorphine treatmentMu-opioid receptor availabilityAgonist opioid treatmentMultimodal analgesic strategyAnti-inflammatory drugsLong-term buprenorphine treatmentAnalgesic strategiesNonopioid adjunctsOpioid treatmentPerioperative strategiesHospital dischargePerioperative managementBuprenorphine formulationsSimultaneous administrationRegional anesthesiaEffective treatmentUse disordersReceptor availabilityMultidisciplinary approachBuprenorphinePatientsTreatmentPainAnesthesia
2020
Cardiac Surgeons’ Treatment Approaches for Infective Endocarditis Based on Patients’ Substance Use History
Nguemeni Tiako M, Mszar R, Brooks C, Mahmood SUB, Mori M, Geirsson A, Weimer MB. Cardiac Surgeons’ Treatment Approaches for Infective Endocarditis Based on Patients’ Substance Use History. Seminars In Thoracic And Cardiovascular Surgery 2020, 33: 703-709. PMID: 33279690, DOI: 10.1053/j.semtcvs.2020.11.031.Peer-Reviewed Original ResearchConceptsInjection drug use-associated infective endocarditisCardiac surgeonsTreatment approachesInfective endocarditisMethadone treatmentDrug use-associated infective endocarditisMost surgeonsAddiction treatmentLong-term outcomesNumber of surgeriesNon-Hispanic whitesSurvey response rateOperative managementRecurrent infectionsSubstance use historiesOperative approachNative valvePatientsPatient engagementClinical scenariosResponse ratePatients' substanceIDUsSurgeonsAnonymous survey
2018
Lessons Learned from the Implementation of a Medically Enhanced Residential Treatment (MERT) Model Integrating Intravenous Antibiotics and Residential Addiction Treatment
Englander H, Wilson T, Collins D, Phoutrides E, Weimer M, Korthuis PT, Calcagni J, Nicolaidis C. Lessons Learned from the Implementation of a Medically Enhanced Residential Treatment (MERT) Model Integrating Intravenous Antibiotics and Residential Addiction Treatment. Substance Use & Addiction Journal 2018, 39: 225-232. PMID: 29595367, PMCID: PMC6519053, DOI: 10.1080/08897077.2018.1452326.Peer-Reviewed Original ResearchConceptsSubstance use disordersIntravenous antibioticsLong-term intravenous antibioticsSkilled nursing facility admissionsAddiction medicine serviceIntravenous antibiotic coursesNursing facility admissionsResidential SUD treatment facilityResidential treatmentPhysical health needsResidential SUD treatmentSUD treatment facilitiesResidential addiction treatmentAntibiotic coursesResidential treatment modelMixed-methods evaluationChart reviewUntreated painFacility admissionPICC linesSevere infectionsSUD careSUD treatmentMedicine serviceUse disorders
2017
Treating the Symptom but Not the Underlying Disease in Infective Endocarditis: A Teachable Moment
Serota DP, Kraft CS, Weimer MB. Treating the Symptom but Not the Underlying Disease in Infective Endocarditis: A Teachable Moment. JAMA Internal Medicine 2017, 177: 1026-1027. PMID: 28505250, DOI: 10.1001/jamainternmed.2017.1489.Commentaries, Editorials and LettersAnti-Bacterial AgentsEndocarditisEnterococcus faecalisGram-Positive Bacterial InfectionsHeart Valve Prosthesis ImplantationHumansIntracranial EmbolismLost to Follow-UpMaleMitral ValveMitral Valve InsufficiencyOpioid-Related DisordersPatient CompliancePatient ReadmissionProsthesis-Related InfectionsRetreatmentShock, SepticStaphylococcal InfectionsStaphylococcus aureusSubstance Abuse, IntravenousYoung AdultPlanning and Designing the Improving Addiction Care Team (IMPACT) for Hospitalized Adults with Substance Use Disorder
Englander H, Weimer M, Solotaroff R, Nicolaidis C, Chan B, Velez C, Noice A, Hartnett T, Blackburn E, Barnes P, Korthuis PT. Planning and Designing the Improving Addiction Care Team (IMPACT) for Hospitalized Adults with Substance Use Disorder. Journal Of Hospital Medicine 2017, 12: 339-342. PMID: 28459904, PMCID: PMC5542562, DOI: 10.12788/jhm.2736.Peer-Reviewed Original ResearchConceptsImproving Addiction Care TeamSubstance use disordersCare teamCare modelUse disordersAddiction medicine consultation serviceRapid access pathwayLength of stayActive substance useResidential care modelMedicaid accountable care organizationsNeeds assessmentHigh rateHospital payerHospitalized adultsAntibiotic infusionCostly readmissionsComplex patientsAccountable care organizationsSUD treatmentHealthcare costsAddiction careAddiction treatmentHospital medicineSubstance use
2016
Symphalangism
Pasha AS, Weimer M. Symphalangism. Arthritis & Rheumatology 2016, 68: 2327-2327. PMID: 27214152, DOI: 10.1002/art.39752.Peer-Reviewed Case Reports and Technical NotesA Chronic Opioid Therapy Dose Reduction Policy in Primary Care
Weimer MB, Hartung DM, Ahmed S, Nicolaidis C. A Chronic Opioid Therapy Dose Reduction Policy in Primary Care. Substance Use & Addiction Journal 2016, 37: 141-147. PMID: 26685018, DOI: 10.1080/08897077.2015.1129526.Peer-Reviewed Original ResearchConceptsHigh-dose opioidsChronic opioid therapyOpioid therapyOpioid doseDose taperAcademic primary care clinicHigh-dose opioid therapyHigher opioid doseIntervention of educationOpioid dose reductionTotal opioid doseRetrospective cohort studyCharacteristics of patientsPrimary care clinicsOpioid use disorderMedication-assisted treatmentAverage daily doseOnly significant associationMorphine equivalentsOpioid dosesCohort studyPatient characteristicsDaily doseCare clinicsChronic painCorrelates of prescription opioid therapy in Veterans with chronic pain and history of substance use disorder
Lovejoy TI, Dobscha SK, Turk DC, Weimer MB, Morasco BJ. Correlates of prescription opioid therapy in Veterans with chronic pain and history of substance use disorder. The Journal Of Rehabilitation Research And Development 2016, 53: 25-36. PMID: 27005461, DOI: 10.1682/jrrd.2014.10.0230.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyPrescription opioid therapySubstance use disordersOpioid therapyChronic painSUD historyPain diagnosisUse disordersChronic noncancer painVeterans Affairs electronic medical recordsPain-related functioningLow chronic painElectronic medical recordsNoncancer painOpioid medicationsOpioid prescriptionsClinical characteristicsPain severityPain interferencePharmacy dataMedical recordsPainPsychosocial questionnairesPatientsTherapy
2013
Sex Differences in the Medical Care of VA Patients with Chronic Non‐Cancer Pain
Weimer MB, Macey TA, Nicolaidis C, Dobscha SK, Duckart JP, Morasco BJ. Sex Differences in the Medical Care of VA Patients with Chronic Non‐Cancer Pain. Pain Medicine 2013, 14: 1839-1847. PMID: 23802846, PMCID: PMC3866355, DOI: 10.1111/pme.12177.Peer-Reviewed Original ResearchConceptsChronic opioid therapyPain-related diagnosesPrimary care utilizationChronic painOpioid therapyCare utilizationEmergency departmentGreater oddsSevere chronic non-cancer painFemale veteransChronic non-cancer painSex differencesNon-cancer painRetrospective cohort studyInflammatory bowel diseasePhysical therapy referralsLow back painVeterans Affairs systemMultivariate logistic regressionPain-related complaintsVA administrative dataMental health diagnosesSubstance use disordersMore pain conditionsMedical comorbiditiesPatterns of care and side effects for patients prescribed methadone for treatment of chronic pain.
Macey TA, Weimer MB, Grimaldi EM, Dobscha SK, Morasco BJ. Patterns of care and side effects for patients prescribed methadone for treatment of chronic pain. Journal Of Opioid Management 2013, 9: 325-33. PMID: 24353045, PMCID: PMC4001870, DOI: 10.5055/jom.2013.0175.Peer-Reviewed Original ResearchConceptsChronic painSide effectsSingle VA medical centerInitiation of methadoneInsufficient pain reliefCardiac side effectsChronic pain patientsHealth service utilizationPatterns of careMedical record dataVA Medical CenterNew initiationOpioid initiationPain reliefPain patientsQTc prolongationSustained releaseService utilizationClinical dataClinical significanceMedical CenterCalendar year 2008PatientsClinical information systemsMethadone
2011
The Source of Methadone in Overdose Deaths in Western Virginia in 2004
Weimer MB, Korthuis PT, Behonick GS, Wunsch MJ. The Source of Methadone in Overdose Deaths in Western Virginia in 2004. Journal Of Addiction Medicine 2011, 5: 188-202. PMID: 21844834, PMCID: PMC3156987, DOI: 10.1097/adm.0b013e318211c56a.Peer-Reviewed Original ResearchConceptsSource of methadoneOpioid treatment programsMethadone-related deathsOverdose deathsMethadone-related overdose deathsUnintentional poisoning deathsPrescription monitoring programsMajority of deathsCause of deathMedical examiner casesIllicit methadone useChief Medical ExaminerMethadone usePrescription opioidsPoisoning deathsNonprescription useMethadoneTreatment programNonmedical useDeathDecedentsMedical examinersRural VirginiaCurrent studyAnalgesia