Featured Publications
Contribution of Multiple Chronic Conditions to Universal Health Outcomes
Tinetti ME, McAvay GJ, Chang SS, Newman AB, Fitzpatrick AL, Fried TR, Peduzzi PN. Contribution of Multiple Chronic Conditions to Universal Health Outcomes. Journal Of The American Geriatrics Society 2011, 59: 1686-1691. PMID: 21883118, PMCID: PMC3622699, DOI: 10.1111/j.1532-5415.2011.03573.x.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseUniversal health outcomesHeart failureSelf-rated healthCognitive impairmentHealth outcomesChronic conditionsObstructive pulmonary diseaseCardiovascular Health StudyCommunity-living participantsMultiple chronic conditionsPulmonary diseaseBurden ScaleInstrumental activitiesDaily livingCox modelHealth StudyCare prioritiesMore symptomsIADLsDepressionImpairmentOutcomesOsteoarthritisADLsEffect of Chronic Disease–Related Symptoms and Impairments on Universal Health Outcomes in Older Adults
Tinetti ME, McAvay G, Chang SS, Ning Y, Newman AB, Fitzpatrick A, Fried TR, Harris TB, Nevitt MC, Satterfield S, Yaffe K, Peduzzi P. Effect of Chronic Disease–Related Symptoms and Impairments on Universal Health Outcomes in Older Adults. Journal Of The American Geriatrics Society 2011, 59: 1618-1627. PMID: 21883120, PMCID: PMC3287052, DOI: 10.1111/j.1532-5415.2011.03576.x.Peer-Reviewed Original ResearchConceptsUniversal health outcomesChronic obstructive pulmonary diseaseCardiovascular Health StudyHeart failureDisease-related symptomsEjection fractionHF symptomsSelf-rated healthHealth outcomesChronic diseasesCognitive impairmentObstructive pulmonary diseaseBody Composition StudyTarget of therapyDyspnea scaleExpiratory volumeHazard ratioJoint painPulmonary diseaseInstrumental activitiesDaily livingHealth StudyDisease severitySignificant associationSymptomsShared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes.
Tinetti ME, Inouye SK, Gill TM, Doucette JT. Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. JAMA 1995, 273: 1348-53. PMID: 7715059, DOI: 10.1001/jama.273.17.1348.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsActivities of Daily LivingAgedAged, 80 and overAnxietyCausalityCognitionCohort StudiesGeriatric AssessmentHearingHumansLogistic ModelsMultivariate AnalysisNeuropsychological TestsNutritional Physiological PhenomenaPhysical FitnessPsychomotor PerformanceRisk FactorsUrinary IncontinenceVision, OcularConceptsUrinary incontinenceGeriatric syndromesMore basic activitiesProportion of participantsRisk factorsIncontinenceDaily livingDepression scoresSyndromeGeneral communityCompensatory abilityArm strengthBasic activitiesSignificant increaseHigh anxietyImpairmentMultiple areasNew HavenYearsParticipantsFallFactorsPredisposesCohortBaseline
2000
Health, Functional, and Psychological Outcomes Among Older Persons with Chronic Dizziness
Tinetti M, Williams C, Gill T. Health, Functional, and Psychological Outcomes Among Older Persons with Chronic Dizziness. Journal Of The American Geriatrics Society 2000, 48: 417-421. PMID: 10798469, DOI: 10.1111/j.1532-5415.2000.tb04700.x.Peer-Reviewed Original ResearchConceptsSelf-rated healthChronic dizzinessDepressive symptomsInstrumental activitiesDaily livingOlder personsProspective cohort studyGoals of carePotential confounding factorsCohort studyAdverse outcomesDizzinessAge 72Clinical strategiesBaseline levelsConfounding factorsSocial disabilityDiscrete diseaseSymptomsHealth conditionsMarginal significanceHospitalizationSyncopeOutcomesPsychological outcomes
1999
The Combined Effects of Baseline Vulnerability and Acute Hospital Events on the Development of Functional Dependence Among Community-Living Older Persons
Gill T, Williams C, Tinetti M. The Combined Effects of Baseline Vulnerability and Acute Hospital Events on the Development of Functional Dependence Among Community-Living Older Persons. The Journals Of Gerontology Series A 1999, 54: m377-m383. PMID: 10462171, DOI: 10.1093/gerona/54.7.m377.Peer-Reviewed Original ResearchConceptsCommunity-living older personsValidation cohortDevelopment cohortOlder personsBaseline vulnerabilityHospital eventsPopulation-based cohort studyAcute care hospital admissionsCommunity-living personsHigh-risk groupSkilled nursing facilitiesYears of ageCohort studyHospital admissionPrimary outcomeComparable personsNew disabilityDaily livingNursing facilitiesCohortCognitive statusHigh-vulnerability groupPrecipitating eventsPhysical performanceAdmissionAlcohol Use and Functional Disability Among Cognitively Impaired Adults
Reid M, Concaio J, Towle V, Williams C, Tinetti M. Alcohol Use and Functional Disability Among Cognitively Impaired Adults. Journal Of The American Geriatrics Society 1999, 47: 854-859. PMID: 10404931, DOI: 10.1111/j.1532-5415.1999.tb03844.x.Peer-Reviewed Original ResearchConceptsFunctional disabilityIADL scoresHeavy drinkersFormer drinkersMini-Mental Status Examination scoreRetrospective medical record reviewImpaired adultsPotential dose-response effectAlcohol useLower IADL scoresMedical record reviewDose-response effectRecord reviewAlcohol intakeProspective studyConsecutive participantsFunctional statusAlcohol exposureInstrumental activitiesDaily livingIADL functionModerate drinkersCognitive impairmentBADLAlcohol effects
1998
The Effect of Falls and Fall Injuries on Functioning in Community-Dwelling Older Persons
Tinetti M, Williams C. The Effect of Falls and Fall Injuries on Functioning in Community-Dwelling Older Persons. The Journals Of Gerontology Series A 1998, 53A: m112-m119. PMID: 9520917, DOI: 10.1093/gerona/53a.2.m112.Peer-Reviewed Original ResearchConceptsNoninjurious fallsOlder personsInjurious fallsIndependent determinantsPhysical activityFall statusSerious injuriesCommunity-dwelling older personsAdverse functional outcomesCommunity-dwelling personsAge 71 yearsHospital surveillanceMore fallsFunctional outcomeRisk factorsFall injuriesHigh burdenPreventive strategiesFunctional declineInstrumental activitiesOutcome measuresCohort membersDaily livingHierarchical linear regression modelsInjuryMODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program
Reuben D, Fried T, Wachtel T, Tinetti M. MODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program. Journal Of The American Geriatrics Society 1998, 46: 226-231. PMID: 9475454, DOI: 10.1111/j.1532-5415.1998.tb02544.x.Peer-Reviewed Original ResearchConceptsUpper respiratory tract infectionFrail older patientsRespiratory tract infectionsCongestive heart failureMajority of patientsRoutine medical careSevere cognitive impairmentGERIATRICS PRACTICEAcute illnessOlder patientsTract infectionsHeart failureHomebound patientsUnscheduled visitsEmergency roomNurse practitionersDaily livingMedical residency programsPatientsPatient's homeScheduled visitsAmbulatory practiceCognitive impairmentComplex illnessMedical care
1997
Predictors of Recovery in Activities of Daily Living Among Disabled Older Persons Living in the Community
Gill T, Robison J, Tinetti M. Predictors of Recovery in Activities of Daily Living Among Disabled Older Persons Living in the Community. Journal Of General Internal Medicine 1997, 12: 757-762. PMID: 9436895, PMCID: PMC1497202, DOI: 10.1046/j.1525-1497.1997.07161.x.Peer-Reviewed Original ResearchConceptsGood nutritional statusADL functionDisabled older personsNutritional statusADL recoveryDaily livingFolstein Mini-Mental State Examination (MMSE) scoresOlder personsMini-Mental State Examination scoreMarkers of resiliencyProspective cohort studyPredictors of recoveryState Examination scoreIntact cognitive functionCohort studyMultivariable analysisMore ADLsMMSE scoresSelf-efficacy scoresHome assessmentBivariate analysisCognitive functionGeneral communityPhysical performanceADLSystematic home-based physical and functional therapy for older persons after hip fracture
Tinetti M, Baker D, Gottschalk M, Garrett P, McGeary S, Pollack D, Charpentier P. Systematic home-based physical and functional therapy for older persons after hip fracture. Archives Of Physical Medicine And Rehabilitation 1997, 78: 1237-1247. PMID: 9365355, DOI: 10.1016/s0003-9993(97)90338-5.Peer-Reviewed Original ResearchConceptsOlder personsHip fractureBerg Balance Scale scoreStair climbingTherapy componentsPhysical therapy componentTotal ADL scoreBalance Scale scoreHome-based therapyMaximum elbow extensionYears of ageHome-based rehabilitation protocolPercentage of participantsPercent of participantsImpaired older personsDaily exercise sessionsAmeliorate impairmentsADL scoresFractured hipExercise programGait deviationsRehabilitation protocolExercise sessionsDaily livingRehabilitation programThe Role of Change in Physical Performance in Determining Risk for Dependence in Activities of Daily Living Among Nondisabled Community-Living Elderly Persons
Gill T, Williams C, de Leon C, Tinetti M. The Role of Change in Physical Performance in Determining Risk for Dependence in Activities of Daily Living Among Nondisabled Community-Living Elderly Persons. Journal Of Clinical Epidemiology 1997, 50: 765-772. PMID: 9253386, DOI: 10.1016/s0895-4356(97)00065-6.Peer-Reviewed Original ResearchConceptsUseful prognostic informationADL dependencePhysical performanceElderly personsPrognostic informationDaily livingCommunity-living elderly personsSingle assessmentLarge representative cohortAssessment of changesFuture disabilityBaseline interviewRepresentative cohortPowerful predictorRole of changesRiskParticipantsShort intervalsYearsAssessmentBaseline performancePersonsCohortYear interviewsADL
1996
Impairments in Physical Performance and Cognitive Status as Predisposing Factors for Functional Dependence Among Nondisabled Older Persons
Gill T, Williams C, Richardson E, Tinetti M. Impairments in Physical Performance and Cognitive Status as Predisposing Factors for Functional Dependence Among Nondisabled Older Persons. The Journals Of Gerontology Series A 1996, 51A: m283-m288. PMID: 8914500, DOI: 10.1093/gerona/51a.6.m283.Peer-Reviewed Original ResearchConceptsCognitive statusPhysical performanceOlder personsCommunity-living older adultsSlow functional declineWorse physical performanceCommunity-living adultsComplete outcome dataChronic conditionsPredisposing factorsFunctional declineDaily livingOutcome dataCognitive testingOlder adultsImpairmentRiskProbability sampleSubjectsStatusAdultsYearsComprehensive assessmentSimilar resultsFollow
1995
Assessing Risk for the Onset of Functional Dependence Among Older Adults: The Role of Physical Performance
Gill T, Williams C, Tinetti M. Assessing Risk for the Onset of Functional Dependence Among Older Adults: The Role of Physical Performance. Journal Of The American Geriatrics Society 1995, 43: 603-609. PMID: 7775716, DOI: 10.1111/j.1532-5415.1995.tb07192.x.Peer-Reviewed Original ResearchConceptsCommunity-dwelling adultsBasic ADLPhysical performanceOlder adultsMain outcome eventTimed testsPhysical performance testsChair standNew disabilityBaseline interviewOutcome eventsCohort membersDaily livingHigh riskRepresentative cohortRate of dependenceOlder personsRisk assessment strategiesADLRapid gaitBasic activitiesComplete dataAdultsRiskOnsetShared Risk Factors for Falls, Incontinence, and Functional Dependence: Unifying the Approach to Geriatric Syndromes
Tinetti M, Inouye S, Gill T, Doucette J. Shared Risk Factors for Falls, Incontinence, and Functional Dependence: Unifying the Approach to Geriatric Syndromes. JAMA 1995, 273: 1348-1353. DOI: 10.1001/jama.1995.03520410042024.Peer-Reviewed Original ResearchGeriatric syndromesUrinary incontinenceMore basic activitiesPopulation-based cohortProportion of participantsRisk factorsIncontinenceDaily livingDepression scoresSyndromeGeneral communityCompensatory abilityArm strengthBasic activitiesSignificant increaseHigh anxietyImpairmentMultiple areasNew HavenYearsParticipantsFallFactorsPredisposesCohortThe Effects of Exercise on Falls in Elderly Patients: A Preplanned Meta-analysis of the FICSIT Trials
Province M, Hadley E, Hornbrook M, Lipsitz L, Miller J, Mulrow C, Ory M, Sattin R, Tinetti M, Wolf S, Schechtman K, Arfken C, Rossiter-Fornoff J, Stevens V, Wingfield D, Greenlick M, Baker D, Claus E, Horwitz R, Buchner D, Wagner E, de Lateur B, Cress M, Price R, Abrass I, Esselman P, Marguerita T, . C, Mulrow, Gerety M, Cornell J, DeNino L, Kanten D, Kutner N, Green R, McNeely E, Coogler C, Fiatarone M, O'Neill E, Ryan N, Diet T, Clements K, Kehayias J, Roberts S, Evans W, Wallace R, Ross J, Huston J, Kundel C, Sellberg M, Wolfson L, Whipple R, Amerman P, Judge J, Derby C, King M, Tamboli A, Weiss S. The Effects of Exercise on Falls in Elderly Patients: A Preplanned Meta-analysis of the FICSIT Trials. JAMA 1995, 273: 1341-1347. DOI: 10.1001/jama.1995.03520410035023.Peer-Reviewed Original ResearchElderly patientsTreatment armsExercise componentLower extremity weaknessAndersen-Gill extensionEffects of exerciseFall-related injuriesRisk of fallsShort-term exerciseFall outcomesFICSIT TrialsExtremity weaknessMedication changesInjurious fallsIncidence ratiosGeneral exerciseMedical recordsClinical trialsTai ChiDaily livingHigh riskCox modelNursing homesElderly adultsMeta-Analysis