2008
Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve
Pal L, Zhang K, Zeitlian G, Santoro N. Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve. Fertility And Sterility 2008, 93: 1074-1079. PMID: 19100532, DOI: 10.1016/j.fertnstert.2008.10.069.Peer-Reviewed Original ResearchConceptsDiminished ovarian reserveReproductive hormone profilesOvarian reserveInfertile womenUrinary excretionMenstrual cycleHealthy controlsHormone profilesAge-comparable healthy controlsUrinary FSH levelsProspective observational studyEarly follicular phaseEntire menstrual cycleAge-comparable controlsMetabolites of estrogenFSH levelsHormone milieuInfertility practiceMenopause transitionUrine voidsFollicular phaseEstrone conjugatesFSH surgeObservational studyMAIN OUTCOMEDiminished ovarian reserve in a woman with a balanced 13;21 translocation
Kummer N, Martin JR, Pal L. Diminished ovarian reserve in a woman with a balanced 13;21 translocation. Fertility And Sterility 2008, 91: 931.e3-931.e5. PMID: 18829026, DOI: 10.1016/j.fertnstert.2008.07.1726.Peer-Reviewed Original ResearchConceptsOvarian reservePrimary infertilityDecreased ovarian reserveUniversity Teaching HospitalLaboratory evaluationBalanced autosomal translocationEndocrinologic evaluationConcomitant findingsEarly menopauseInfertility practiceUnknown etiologyCase reportCaucasian womenTeaching hospitalMAIN OUTCOMEFamilial historyReproductive endocrinologySemen analysisBalanced translocationInfertilityPossible roleDiagnosisWomenAutosomal translocationsKaryotype analysisLess is more: increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization
Pal L, Jindal S, Witt BR, Santoro N. Less is more: increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization. Fertility And Sterility 2008, 89: 1694-1701. PMID: 18440515, PMCID: PMC2601677, DOI: 10.1016/j.fertnstert.2007.05.055.Peer-Reviewed Original ResearchConceptsNondonor IVF cyclesClinical pregnancyCycle cancellationLive birthsGonadotropin useIVF cyclesSpontaneous miscarriageOvarian reserve statusOvarian hyperstimulation resultsHigh gonadotropinsOvarian stimulationFertilization cyclesIVF outcomesOocyte yieldWorse prognosisRetrospective studyIVF centerImproved outcomesAggressive approachMAIN OUTCOMEPregnancyIVFHigher likelihoodBirthOutcomes
2004
Postthaw blastomere survival is predictive of the success of frozen–Thawed embryo transfer cycles
Pal L, Kovacs P, Witt B, Jindal S, Santoro N, Barad D. Postthaw blastomere survival is predictive of the success of frozen–Thawed embryo transfer cycles. Fertility And Sterility 2004, 82: 821-826. PMID: 15482754, DOI: 10.1016/j.fertnstert.2004.02.136.Peer-Reviewed Original ResearchConceptsEmbryo transfer cyclesFET cyclesBlastomere survivalImplantation rateTransfer cyclesFrozen-thawed embryo transfer cyclesClinical pregnancy rateTertiary care facilitySerum P levelsClinical pregnancyHCG administrationInfertile womenRetrospective studyInverse associationIVF unitPregnancy rateMAIN OUTCOMECare facilitiesPregnancySurvivalOutcomesEmbryo survivalLower survivalHigher survivalAdministration
1999
Effect of a baseline ovarian cyst on the outcome of in vitro fertilization–embryo transfer
Segal S, Shifren J, Isaacson K, Leykin L, Chang Y, Pal L, Toth T. Effect of a baseline ovarian cyst on the outcome of in vitro fertilization–embryo transfer. Fertility And Sterility 1999, 71: 274-277. PMID: 9988397, DOI: 10.1016/s0015-0282(98)00449-x.Peer-Reviewed Original ResearchConceptsBaseline ovarian cystsOvarian cystsHCG administrationE2 levelsPregnancy rateDay 3Cycle day 3Fertilization-embryo transferOutcome of IVFNumber of folliclesNumber of oocytesNumber of embryosBaseline cystOvarian hyperstimulationIVF-ETPoor outcomeRetrospective studyUltrasound examinationMAIN OUTCOMEAcademic centersFertilization unitCystsPatientsMature oocytesOutcomes