2000
Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection
Onyeji C, Nicolau D, Nightingale C, Bow L. Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection. Journal Of Antimicrobial Chemotherapy 2000, 46: 429-436. PMID: 10980170, DOI: 10.1093/jac/46.3.429.Peer-Reviewed Original ResearchConceptsGranulocyte colony-stimulating factorG-CSFColony-stimulating factorInfected animalsNeutropenic miceFaecalis infectionDisposition of vancomycinNon-neutropenic animalsEnterococcus faecalis infectionPharmacokinetics of antibioticsInduction of neutropeniaConcentration-time curveEfficacy of gentamicinDose-dependent increaseE. faecalis infectionNeutropenic patientsPharmacokinetic interactionsDosing regimensSame infectionPlasma clearanceUseful adjunctGentamicinInfectionVancomycinMice
1999
Influence of adjunctive interferon-γ on treatment of gentamicin- and vancomycin-resistant Enterococcus faecalis infection in mice
Onyeji C, Bui K, Nicolau D, Nightingale C, Bow L, Quintiliani R. Influence of adjunctive interferon-γ on treatment of gentamicin- and vancomycin-resistant Enterococcus faecalis infection in mice. International Journal Of Antimicrobial Agents 1999, 12: 301-309. PMID: 10493606, DOI: 10.1016/s0924-8579(99)00055-2.Peer-Reviewed Original ResearchConceptsIFN-gammaFaecalis infectionDisposition of gentamicinInfected neutropenic miceNon-neutropenic miceTreatment of gentamicinSerious enterococcal infectionsEnterococcus faecalis infectionNew treatment optionsE. faecalis infectionOutcome of therapyActivity of gentamicinE. faecalis clinical isolatesDose-dependent mannerPharmacokinetic interactionsConcurrent administrationDosing regimensNeutropenic miceCombination therapyInfectious burdenTreatment optionsEnterococcal infectionsIntraperitoneal inoculationClinical isolatesInfected animals
1992
Late graft loss in cadaveric renal transplantation.
Bergmann L, Roper L, Bow L, Hull D, Bartus S, Schweizer R. Late graft loss in cadaveric renal transplantation. Transplantation Proceedings 1992, 24: 2718-9. PMID: 1465913.Peer-Reviewed Original Research
1989
Transplantation of cadaver kidneys from pediatric and older donors.
Bow L, Roper L, Bartus S, Hull D, Schweizer R. Transplantation of cadaver kidneys from pediatric and older donors. Transplantation Proceedings 1989, 21: 1938-9. PMID: 2652632.Peer-Reviewed Original Research
1988
Renal transplantation at Hartford Hospital: results of combined and flexible immunosuppression.
Schweizer R, Bow L, Roper L, Hull D, Bartus S. Renal transplantation at Hartford Hospital: results of combined and flexible immunosuppression. Clinical Transplants 1988, 147-58. PMID: 3154467.Peer-Reviewed Original ResearchConceptsLiving-related donor kidney transplantsDonor kidney transplantsCadaver kidney transplant recipientsKidney transplant recipientsGraft survivalKidney transplantOKT3 therapyTriple immunosuppressionTransplant recipientsHartford HospitalControl groupPretransplant blood transfusionsPrevious control groupSteroid-resistant rejectionUse of OKT3Year graft survivalMean serum creatinineEuro-Collins solutionAddition of CsAKidney transplantationRenal transplantationCMV infectionSerum creatinineBlood transfusionDR matching