Kirsha Gordon, PhD, MS
Research ScientistCards
Appointments
Contact Info
About
Titles
Research Scientist
Biography
Dr. Gordon is a Research Scientist, Biostatistician and Epidemiologist at the Yale School of Medicine. She is a key contributor in the IMPOWR-YOU (Integrative Management of Chronic Pain and Opioid Use Disorder for Whole Recovery-Yale and Organizations United) Research Center and the PRIME (Pain Research, Informatics, Multimorbidities, and Education) Center of Excellence. She has also collaborated with VACS/COMpAAS, the NIH-DoD-VA Pain Management Collaboratory Coordinating Center (PMC3), the National Women Veterans Hormone Replacement Therapy Study, the Women Veterans Cohort Study (WVCS), the VA Connecticut Healthcare System, and the Social Ties Associated with Risk of Transition into Injection Drug Use Study (START). She received her bachelor’s degree in Mathematics from Manhattan College, and a Masters in Biostatistics and Ph.D. in Epidemiology from Columbia University. She collaborates with clinical investigators from Yale and VA Connecticut on a wide range of biomedical and public health research projects, including researching the interplay of opioids, substance use, and polypharmacy in veterans. She has conducted research using both survey data and large integrated electronic health records, and is particularly interested in the disparity in care by gender, race, and sexual orientation. She has overseen study design, methodology, data coordination, and biostatistical efforts including but not limited to analyzing longitudinal data.
Appointments
General Internal Medicine
Research ScientistPrimary
Other Departments & Organizations
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Amy Justice, MD, PhD
Robert Kerns, PhD
Joseph Lucien Goulet, PhD, MS
Julie R Gaither, PhD, MPH, RN
Declan Barry, PhD
Christopher T Rentsch, PhD, FISPE
Publications
2024
Pain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV
Miller E, McGinnis K, Edelman E, Feinberg T, Gordon K, Kerns R, Marshall B, Patterson J, McRae M. Pain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV. AIDS And Behavior 2024, 1-11. PMID: 39264485, DOI: 10.1007/s10461-024-04494-w.Peer-Reviewed Original ResearchAltmetricConceptsMental health classesSubstance use disordersOpioid use disorderHIV statusBuprenorphine initiationVeterans Aging Cohort StudyInitiate buprenorphineMental health diagnosesAging Cohort StudyBuprenorphine treatmentMultiple pain conditionsAssociated with HIV statusInfluence treatment retentionUse disorderTreatment of opioid use disorderHigher comorbidity burdenAge of patientsClinical encountersMental healthHealth diagnosisBlack veteransHealth classesLatent class analysisCohort studyPrescription dataMedications for alcohol‐use disorder and follow‐up after hospitalization for alcohol withdrawal: A multicenter study
Allaudeen N, Akwe J, Arundel C, Boggan J, Caldwell P, Cornia P, Cyr J, Ehlers E, Elzweig J, Godwin P, Gordon K, Guidry M, Gutierrez J, Heppe D, Hoegh M, Jagannath A, Kaboli P, Krug M, Laudate J, Mitchell C, Pescetto M, Rodwin B, Ronan M, Rose R, Shah M, Smeraglio A, Trubitt M, Tuck M, Vargas J, Yarbrough P, Gunderson C. Medications for alcohol‐use disorder and follow‐up after hospitalization for alcohol withdrawal: A multicenter study. Journal Of Hospital Medicine 2024 PMID: 39031461, DOI: 10.1002/jhm.13458.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAlcohol-use disordersResidential treatment programAlcohol withdrawalFollow-up appointmentsImprove abstinenceAll-cause 30-day readmissionFollow-upTreatment programsReturn to heavy drinkingAssociated with improved outcomesRetrospective cohort studyOutpatient follow-upEffects of medicationAssociated with readmissionTime of dischargeVeterans Health Administration hospitalsAssociated with decreased readmissionMulticenter studyAcute care hospitalsAssociated with reduced 30-day readmissionsResidential programsPrescription of medicationsAbstinenceCohort studyHeavy drinkingContribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study
Guillot J, Justice A, Gordon K, Skanderson M, Pariente A, Bezin J, Rentsch C. Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study. Journal Of General Internal Medicine 2024, 1-10. PMID: 38831248, DOI: 10.1007/s11606-024-08817-4.Peer-Reviewed Original ResearchAltmetricConceptsMiddle-aged patientsRisk of mortalityVeterans AffairsChronic medicationsVA patient populationIntegrated healthcare systemNational cohort studyAssociated with increased mortalityMiddle-aged individualsMechanism of injuryMiddle-aged peopleAssociated with mortalityInappropriate medicationsBeers criteriaHealthcare systemAttenuate riskCohort studyClinical characteristicsGeneral populationHyperpolypharmacyFollow-upPolypharmacyPatient populationBackgroundThe roleCox modelPatterns of gabapentin prescription and of hospitalization in a national cohort of US Veterans
Levy D, Gordon K, Bastian L, Brandt C, Gunderson C. Patterns of gabapentin prescription and of hospitalization in a national cohort of US Veterans. Pain Medicine 2024, 25: 534-537. PMID: 38676664, DOI: 10.1093/pm/pnae027.Peer-Reviewed Original ResearchAltmetricContemporary Management and Outcomes of Veterans Hospitalized With Alcohol Withdrawal: A Multicenter Retrospective Cohort Study
Ronan M, Gordon K, Skanderson M, Krug M, Godwin P, Heppe D, Hoegh M, Boggan J, Gutierrez J, Kaboli P, Pescetto M, Guidry M, Caldwell P, Mitchell C, Ehlers E, Allaudeen N, Cyr J, Smeraglio A, Yarbrough P, Rose R, Jagannath A, Vargas J, Cornia P, Shah M, Tuck M, Arundel C, Laudate J, Elzweig J, Rodwin B, Akwe J, Trubitt M, Gunderson C. Contemporary Management and Outcomes of Veterans Hospitalized With Alcohol Withdrawal: A Multicenter Retrospective Cohort Study. Journal Of Addiction Medicine 2024, 18: 389-396. PMID: 38452185, DOI: 10.1097/adm.0000000000001297.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSymptom-triggered therapyRetrospective cohort studyTreatment durationComplicated withdrawalVeterans Health AdministrationAlcohol withdrawalFixed doseFactors associated with treatment durationCohort studyMulticenter retrospective cohort studyFixed-dose regimensLong-acting benzodiazepinesVeterans Health Administration Corporate Data WarehouseShort-acting benzodiazepineAmerican Society of Addiction Medicine (ASAMAlcohol withdrawal managementChart reviewHealth care systemCorporate Data WarehouseOutcomes of veteransInpatient managementTherapyWithdrawal managementHospital outcomesManagement pathway
2023
The Association of Prescribed Opioids and Incident Cardiovascular Disease
Sung M, Eden S, Becker W, Crystal S, Duncan M, Gordon K, Kerns R, Kundu S, Freiberg M, So-Armah K, Edelman E. The Association of Prescribed Opioids and Incident Cardiovascular Disease. Journal Of Pain 2023, 25: 104436. PMID: 38029949, PMCID: PMC11058015, DOI: 10.1016/j.jpain.2023.11.019.Peer-Reviewed Original ResearchCitationsAltmetricConceptsIncident cardiovascular diseaseModifiable CVD risk factorsCVD risk factorsHuman immunodeficiency virusCardiovascular diseasePrescribed opioidsOpioid receiptRisk factorsUse disordersCox proportional hazards regression modelVeterans Aging Cohort StudyVeterans Health Administration (VHA) carePropensity scoreProportional hazards regression modelsCVD incidence ratesPrescription opioid exposureIncident CVD eventsPrevalence of hypertensionAging Cohort StudyHigher opioid dosesOpioid use disorderHazards regression modelsNational prospective cohortVeterans Administration dataCocaine use disorderOpioid prescription and risk of atrial fibrillation in younger veterans
Chui P, Khokhar A, Gordon K, Dziura J, Burg M, Brandt C, Haskell S, Malm B, Bastian L, Gandhi P. Opioid prescription and risk of atrial fibrillation in younger veterans. American Heart Journal 2023, 268: 61-67. PMID: 37949420, DOI: 10.1016/j.ahj.2023.11.001.Peer-Reviewed Original ResearchAltmetricConceptsTime-updated Cox regressionIncident atrial fibrillationAtrial fibrillationOpioid exposureVeterans Health AdministrationOpioid typeCox regressionOpioid prescriptionsICD-9-CM diagnostic codesIncidence of AFDevelopment of AFPrescription opioid exposureModifiable risk factorsPrimary care visitsPrescribed opioidsCare visitsOpioid useRisk factorsDiagnostic codesTime-dependent variablesOpioidsHealth AdministrationYounger veteransBaseline periodStudy sampleRelationship Between Pain and LGBT Status Among Veterans in Care in a Retrospective Cross-Sectional Cohort
Gordon K, Buta E, Pratt-Chapman M, Brandt C, Gueorguieva R, Warren A, Workman T, Zeng-Treitler Q, Goulet J. Relationship Between Pain and LGBT Status Among Veterans in Care in a Retrospective Cross-Sectional Cohort. Journal Of Pain Research 2023, 16: 4037-4047. PMID: 38054108, PMCID: PMC10695019, DOI: 10.2147/jpr.s432967.Peer-Reviewed Original ResearchAltmetricConceptsRetrospective cross-sectional cohortCross-sectional cohortPersistent painSelf-reported pain scoresVeterans Health AdministrationRobust Poisson modelsCorporate Data WarehouseLGBT veteransPain screeningPain scoresClinic visitsPain assessmentPainAdjusted modelHealth AdministrationGreater painMental healthSubstance useCohortYear of entryBlack veteransHealthcare systemVeteransSignificant differencesAdministrative dataGraded chronic pain scale revised: validation in a Veteran sample
Taub C, Gordon K, Goulet J, Lee A, Mayhew M, Von Korff M, DeBar L, Kerns R. Graded chronic pain scale revised: validation in a Veteran sample. Pain Medicine 2023, 24: 1169-1175. PMID: 37220899, PMCID: PMC10546477, DOI: 10.1093/pm/pnad068.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsGraded Chronic Pain ScaleHigh-impact chronic painAdjusted odds ratioMild chronic painChronic Pain ScaleChronic painPain scaleConfidence intervalsLong-term opioid therapyHigh-risk populationOpioid therapyPain gradeUS veteransOdds ratioActivity limitationsPainPain researchLogistic regressionVeteran sampleHealth indicatorsStudy objectiveConvergent validityValidation studyVeteransPsychological variablesEstimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis
Carey G, Holleck J, Alshaeba S, Jayakrishnan R, Gordon K, Grimshaw A, Gunderson C. Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2023, 78: 1150-1159. PMID: 36964648, DOI: 10.1093/jac/dkad078.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCommon infectious syndromesEmpirical antibioticsPrevalence of MRSAInfectious syndromesMRSA infectionIll patientsMortality rateSystematic reviewAbsolute mortality benefitAnti-MRSA therapyEmpirical antibiotic coverageLow-risk infectionsSoft tissue infectionsUrinary tract infectionAbsolute risk reductionMethicillin-resistant Staphylococcus aureusCatheter-related infectionsStudy of patientsBaseline mortality ratesSystematic literature searchWeb of ScienceMRSA coverageAntibiotic coverageEmpirical antimicrobialsMortality benefit
News
News
- May 04, 2023
Department of Internal Medicine Promotions
- October 31, 2022
Several Yale Program in Addiction Medicine Faculty Members Receive New NIH HEAL Initiative Awards
- October 13, 2021
NIH Funds $11.8 Million Research Center at Yale on Opioid Use Disorder, Opioid Misuse, and Chronic Pain
- May 12, 2021
Discoveries & Impact (May 2021)