2010
The Effect of Steatosis on Echogenicity of Colorectal Liver Metastases on Intraoperative Ultrasonography
van Vledder MG, Torbenson MS, Pawlik TM, Boctor EM, Hamper UM, Olino K, Choti MA. The Effect of Steatosis on Echogenicity of Colorectal Liver Metastases on Intraoperative Ultrasonography. JAMA Surgery 2010, 145: 661-667. PMID: 20644129, DOI: 10.1001/archsurg.2010.124.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesIntraoperative ultrasonographyLiver metastasesTumor echogenicityLiver tissueExtent of steatosisEffect of steatosisCauses of steatosisFatty liver tissueJohns Hopkins HospitalNontumorous liver tissuesUltrasonography imagesSurgical therapyHistopathologic reviewLiver steatosisProspective studyHepatic steatosisSevere steatosisLiver surgeryPathological dataConspicuity of lesionsSteatosisPatientsEchogenicityUltrasonography
2007
Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome
Pawlik TM, Olino K, Gleisner AL, Torbenson M, Schulick R, Choti MA. Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome. Journal Of Gastrointestinal Surgery 2007, 11: 860-868. PMID: 17492335, DOI: 10.1007/s11605-007-0149-4.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesPreoperative chemotherapyHepatic colorectal metastasesHepatic injuryChemotherapy groupColorectal metastasesHepatic resectionLiver metastasesFluoropyrimidine-based regimensPerioperative complication rateMajority of patientsChemotherapy detailsEligible patientsChemotherapy regimenPerioperative morbidityComplication ratePostoperative outcomesClinicopathologic characteristicsLiver injurySinusoidal dilatationHepatic histologyNontumorous liverSuch injuriesChemotherapyPatients