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Jill Lacy, MD

Professor of Medicine (Medical Oncology)
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About

Titles

Professor of Medicine (Medical Oncology)

Biography

Dr. Jill Lacy is Professor of Medicine in the Section of Medical Oncology at Yale School of Medicine with over 30 years of experience as a practicing Medical Oncologist. Dr. Lacy graduated from Yale School of Medicine in 1978, completed training in Internal Medicine and Medical Oncology at Yale, and is board-certified in Internal Medicine and Medical Oncology. Dr. Lacy's early career was focused on clinical and basic research related to Epstein Barr virus-mediated oncogenesis and HIV-associated malignancies during the height of the AIDS epidemic. In recent years, Dr. Lacy's clinical practice has been devoted to caring for patients with gastrointestinal malignancies. Her current research is focused on therapeutic clinical trials in GI malignancies, including gastroesophageal, pancreatic, and colorectal cancers. She is the principle investigator on a number of investigator-initiated, pharmaceutical, and cooperative group studies. She has served on national committees focused on optimizing the education of Medical Oncology trainees and recruiting minority students to careers in Oncology.

Appointments

Other Departments & Organizations

Education & Training

Fellow
Yale University School of Medicine (1985)
Resident
Yale University School of Medicine (1982)
MD
Yale University (1978)

Research

Overview

Dr. Jill Lacy is a Professor of Medicine in the Section of Medical Oncology at the Yale School of Medicine. She has a large clinical practice in the Gastrointestinal Malignancies Unit at Smilow Cancer Center. After transitioning from lab-based basic research in the field of EBV-associated malignancies, she has been actively engaged in clinical investigation, focusing on therapeutic clinical trials. She has developed and conducted several investigator-initiated trials, and, in addition, has served as the site Principle Investigator on dozens of cooperative group and industry sponsored trials, leading to co-authorship in high impact journals. Her specific research interests include discovery of novel therapeutics for gastroesophageal and pancreatic cancers. In her role as an investigator in the Smilow Cancer Center Disease Aligned Research Team for GI Malignancies, she has been instrumental in developing the clinical trials portfolio and fostering translational research for GI Cancers at Yale. In addition to her involvement in patient care and research, Dr. Lacy served at the Program Director of the Hematology-Medical Oncology Fellowship Program at Yale for over 20 years, playing an active role in mentoring Fellows in their research projects and development. Aligned with this commitment to education, she has been actively involved in ASCO in issues related to trainee education, including service as Editor of the ASCO Self-Evaluation Program.

Research at a Glance

Yale Co-Authors

Frequent collaborators of Jill Lacy's published research.

Publications

2024

2023

Clinical Trials

Academic Achievements & Community Involvement

  • honor

    Fellow

  • honor

    America's Top Doctors (digital guide): 2016, 2017, 2018, 2019, 2020, 2021

  • honor

    Exceptional Women In Medicine

  • honor

    Castle Connolly America's Top Doctors for Cancer (digital guide): 2016, 2017, 2018, 2019, 2020, 2021

  • honor

    Top Doctors for Cancer, Newsweek Magazine July 2015

Clinical Care

Overview

Jill Lacy, MD, is a medical oncologist who specializes in gastrointestinal (GI) cancers, including pancreatic and colorectal cancers.

Dr. Lacy works with patients using chemotherapy (which destroys cancer cells with chemicals), immunotherapy (which uses drugs to harness the immune system to fight cancer), and targeted therapy (which targets proteins that control how cancer cells behave).

An active researcher, Dr. Lacy has published studies examining the outcomes of targeted therapy and GI cancers, including potentially harmful side effects, and different treatments for metastatic pancreatic cancer.

In 2020, Dr. Lacy was one of five physicians receiving a Yale Medicine Distinguished Clinical Career Award. The award highlights doctors whose careers demonstrate significant accomplishments and dedication.

Clinical Specialties

Medical Oncology

Fact Sheets

Board Certifications

  • Internal Medicine

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1982

Yale Medicine News

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Contacts

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Locations

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