Featured Publications
Examining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials. International Journal Of Eating Disorders 2019, 53: 20-30. PMID: 31497876, PMCID: PMC6983351, DOI: 10.1002/eat.23167.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyCognitive behavioral therapySelf-report measuresModerators of outcomeTreatment outcomesBehavioral weight lossStatistical Manual-Fourth EditionSignificant moderatorWeight lossControl conditionModeratorCourse of treatmentBetter treatment outcomesGreater weight lossMain effectStructured interviewsTreatment settingsPsychopathologyMultimodal treatmentPatient groupRCT studiesMedical CenterBed treatmentParticipantsWeighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa
Galbraith K, Elmquist J, White MA, Grilo CM, Lydecker JA. Weighty decisions: How symptom severity and weight impact perceptions of bulimia nervosa. International Journal Of Eating Disorders 2019, 52: 1035-1041. PMID: 31240769, PMCID: PMC6779161, DOI: 10.1002/eat.23125.Peer-Reviewed Original ResearchConceptsBulimia nervosaSymptom frequencySerious mental health concernsMental health concernsPatient weightWeight statusMental illnessSymptom severityOverweightYoung womenHealth concernWeight stigmaSignificant differencesPatientsNervosaCurrent studyParticipantsVariables of interestIllnessNegative attitudesSeverityWomenExamining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials. Journal Of Consulting And Clinical Psychology 2019, 87: 530-540. PMID: 31008634, PMCID: PMC6589831, DOI: 10.1037/ccp0000404.Peer-Reviewed Original ResearchConceptsBinge-eating disorderWhite participantsCognitive behavioral therapySelf-report measuresTreatment outcomesBinge-eating remissionModerate treatment outcomeBinge Eating DisorderBinge-eating episodesMain effectBlack participantsWeight lossBehavioral weight lossEvidence-based treatmentsLower depressionTreatment researchRandomized Controlled TrialsBetter treatment outcomesControl conditionParticipantsControlled TrialsMultimodal treatmentPercent weight lossPatient groupModeratorFood insecurity and bulimia nervosa in the United States
Lydecker JA, Grilo CM. Food insecurity and bulimia nervosa in the United States. International Journal Of Eating Disorders 2019, 52: 735-739. PMID: 30920683, PMCID: PMC6555671, DOI: 10.1002/eat.23074.Peer-Reviewed Original ResearchI didn't want them to see: Secretive eating among adults with binge‐eating disorder
Lydecker JA, Grilo CM. I didn't want them to see: Secretive eating among adults with binge‐eating disorder. International Journal Of Eating Disorders 2019, 52: 153-158. PMID: 30623972, PMCID: PMC6368878, DOI: 10.1002/eat.23002.Peer-Reviewed Original ResearchConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyObjective binge-eating episodesSecretive eatingBinge-eating episodesGreater eating-disorder psychopathologyGreater body mass indexHigher depression scoresClinical characteristicsMass indexTreatment-seeking adultsDepression scoresPatientsShape/weightWeight concernsAdultsEatingSelf-report measuresDisordersShape concernsEpisodesGreater proportionPsychopathologyTreatment formulationForm and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder
Lydecker JA, White MA, Grilo CM. Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder. Journal Of Consulting And Clinical Psychology 2017, 85: 1095-1103. PMID: 29083224, PMCID: PMC5679782, DOI: 10.1037/ccp0000258.Peer-Reviewed Original ResearchConceptsBody image variablesBody image disturbanceBody image constructsBinge-eating disorderImage constructImage variablesWeight/shape overvaluationBinge-eating frequencyInvestigator-based interviewBiopsychosocial featuresEating-disorder psychopathologyTreatment-seeking patientsShape preoccupationShape dissatisfactionShape overvaluationShape concernsCore aspectsCurrent studyTreatment formulationConstructsImportant distinctionDifferent aspectsOvervaluationPreoccupationDisordersDoes your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape
Lydecker JA, Grilo CM. Does your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape. Preventive Medicine 2017, 105: 265-270. PMID: 28987340, PMCID: PMC5659758, DOI: 10.1016/j.ypmed.2017.10.009.Peer-Reviewed Original ResearchConceptsWeight/shapeParental overvaluationPersonal weightEating-disorder psychopathologyBinge-eating disorderEating PsychopathologyParent psychopathologyPediatric obesityDearth of researchChild weightCross-sectional designParental attitudesPsychopathologyImportant psychopathologyDisorder treatmentCross-sectional studyParentsCurrent studyIntegral stakeholdersWeight influenceOvervaluationClinical attentionChild BMIChild healthRelated conceptsChildren of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOBFathers and mothers with eating-disorder psychopathology: Associations with child eating-disorder behaviors
Lydecker JA, Grilo CM. Fathers and mothers with eating-disorder psychopathology: Associations with child eating-disorder behaviors. Journal Of Psychosomatic Research 2016, 86: 63-69. PMID: 27302549, PMCID: PMC4911698, DOI: 10.1016/j.jpsychores.2016.05.006.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyEating-disordered behaviorChild body mass index (BMI) z-scoreBody mass index z-scoreSample of parentsChild feeding difficultiesCore eating disorder psychopathologyIndex z-scoreBinge-eating disorderParental feeding practicesEating Disorder PsychopathologyFeeding difficultiesChild weightChildren's dietsChildren's eatingMaternal concernClinical concernFeeding practicesBulimia nervosaEating Disorder BehaviorsAnorexia nervosaZ-scorePsychosocial causesClinical interventionsClinical programsCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2024
Associations among parents' internalized weight bias, negative child-focused body talk, and feeding behaviors
Winograd D, Goldschmidt A, Lydecker J. Associations among parents' internalized weight bias, negative child-focused body talk, and feeding behaviors. Eating Behaviors 2024, 52: 101848. PMID: 38308903, PMCID: PMC10922654, DOI: 10.1016/j.eatbeh.2024.101848.Peer-Reviewed Original ResearchConceptsNegative body talkChild genderAssociated with concernsChild well-beingBody talkChildren's dietsChild weightFeeding practicesFamily-focused interventionsExplicit concernWeight biasParenting behaviorsWeight categoriesInfluence parents' feeding practicesWell-beingParental feeding practicesGenderParental concernsMaladaptive eating behaviorsWeight statusParentsEating behaviorsTalkChildrenInternalized weight bias
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlaceboReframing How Providers Advocate for Adolescent Well-Being in Body Image, Eating, and Weight
Ozbardakci E, Lydecker J. Reframing How Providers Advocate for Adolescent Well-Being in Body Image, Eating, and Weight. Journal Of The American Academy Of Child & Adolescent Psychiatry 2023, 62: 957-962. PMID: 36948394, PMCID: PMC10728998, DOI: 10.1016/j.jaac.2023.03.008.Peer-Reviewed Original ResearchConceptsWeight-based victimizationBody imageWeight-based stigmaNegative mental health consequencesAdolescents' body imagePositive body imageMental health consequencesAdolescent Well-BeingCritical developmental periodBody dissatisfactionAdolescent vulnerabilityImage messagesWeight biasBody concernsAdolescents' homesWell-BeingHealth care providersDevelopmental periodAdolescentsEatingCare providersVictimizationPrevention programsHealth consequencesBody shapeLoss of control in binge‐eating disorder: Fear and resignation
Perelman H, Gilbert K, Grilo C, Lydecker J. Loss of control in binge‐eating disorder: Fear and resignation. International Journal Of Eating Disorders 2023, 56: 1199-1206. PMID: 36920120, PMCID: PMC10247475, DOI: 10.1002/eat.23929.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive-affective experiencesLoss of controlModerate treatment outcomeBinge-eating episodesEating-disorder psychopathologyTreatment-seeking patientsFuture researchAbsence of fearGreater distressPsychopathologyFearSevere psychopathologyResearch cliniciansSemistructured interviewsTreatment formulationPast monthDisordersResignationTreatment outcomesExperienceBlack individualsEmotionsTreatment planningIndividuals
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measures
2020
Distinctiveness and significance of body dissatisfaction and overvaluation among Latinx/Hispanic and White men and women
Lydecker JA, Cotter EW, Grilo CM. Distinctiveness and significance of body dissatisfaction and overvaluation among Latinx/Hispanic and White men and women. International Journal Of Eating Disorders 2020, 54: 354-364. PMID: 33247450, PMCID: PMC7956228, DOI: 10.1002/eat.23413.Peer-Reviewed Original ResearchConceptsOvervaluation of weightBody image constructsDisorder psychopathologyWeight-related variablesBody imageImage constructBinge-eating frequencyAssociation of dissatisfactionBody dissatisfactionOnline batteryPsychopathologyWhite individualsCultural variablesDissatisfactionMain effectOvervaluationDepressionImportant distinctionDistinctivenessConstructsIndividualsFurther researchHispanic individualsHispanic adultsParticipantsNaltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityDoes Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support
Ivezaj V, Lydecker JA, Wiedemann AA, Duffy AJ, Grilo CM. Does Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support. Obesity 2020, 28: 1645-1651. PMID: 32729221, PMCID: PMC7484317, DOI: 10.1002/oby.22876.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery Version interviewBariatric surgeryEpisode groupBinge sizeFunctional impairmentDepressive symptomsNew classification systemMental health-related qualityLoss of controlPostsurgical bariatric patientsSurgery 6 monthsHealth-related qualityCross-sectional studyBinge-eating episodesQuality of lifeObjective binge-eating episodesBariatric patientsClinical outcomesEating Disorder PsychopathologyBinge-eating groupBinge eatingSurgeryClassification systemDistinct psychopathologySymptomsLanguage Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery
Ivezaj V, Lydecker JA, Grilo CM. Language Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery. Obesity 2020, 28: 1412-1418. PMID: 32662251, PMCID: PMC7501175, DOI: 10.1002/oby.22868.Peer-Reviewed Original ResearchConceptsHealth care providersBariatric surgeryCare providersCross-sectional studyPatient-centered carePreferred termHealth care systemTreatment trialsPatient preferencesSurgeryBehavioral treatmentControl eatingLanguage preferenceCare systemRacial differencesObesityPatientsWeight biasProvidersBMIWeightIndividualsControlTrialsCare