2014
Evaluation of absorbable mesh fixation devices at various deployment angles
Zihni AM, Cavallo JA, Thompson DM, Chowdhury NH, Frisella MM, Matthews BD, Deeken CR. Evaluation of absorbable mesh fixation devices at various deployment angles. Surgical Endoscopy 2014, 29: 1605-1613. PMID: 25294536, PMCID: PMC4390414, DOI: 10.1007/s00464-014-3850-x.Peer-Reviewed Original Research
2013
Remodeling characteristics and biomechanical properties of a crosslinked versus a non-crosslinked porcine dermis scaffolds in a porcine model of ventral hernia repair
Cavallo J, Greco S, Liu J, Frisella M, Deeken C, Matthews B. Remodeling characteristics and biomechanical properties of a crosslinked versus a non-crosslinked porcine dermis scaffolds in a porcine model of ventral hernia repair. Hernia 2013, 19: 207-218. PMID: 23483265, PMCID: PMC3883946, DOI: 10.1007/s10029-013-1070-2.Peer-Reviewed Original Research
2007
A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair
Leaphart CL, Cavallo J, Gribar SC, Cetin S, Li J, Branca MF, Dubowski TD, Sodhi CP, Hackam DJ. A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair. The Journal Of Immunology 2007, 179: 4808-4820. PMID: 17878380, DOI: 10.4049/jimmunol.179.7.4808.Peer-Reviewed Original ResearchConceptsDevelopment of NECNEC developmentTLR4 activationEnterocyte apoptosisEnterocyte migrationTLR4-mutant C3H/HeJ miceC3H/HeOuJ miceC3H/HeJ miceTranslocation of LPSExpression of TLR4Cause of deathMurine intestinal epitheliumFocal adhesion kinaseNEC severityCritical roleIntestinal injuryMucosal injuryPreterm infantsNecrotizing enterocolitisEnterocyte injuryInflamed intestineIntestinal healingGastrointestinal diseasesHeJ miceIntestinal repairToll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis
Anand RJ, Kohler JW, Cavallo JA, Li J, Dubowski T, Hackam DJ. Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis. Journal Of Pediatric Surgery 2007, 42: 927-933. PMID: 17560196, DOI: 10.1016/j.jpedsurg.2007.01.023.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial TranslocationCell LineDisease Models, AnimalEnterocolitis, NecrotizingEscherichia coliEscherichia coli InfectionsImmunity, InnateLipopolysaccharidesMacrophages, PeritonealMaleMiceMice, Inbred C3HMice, KnockoutPeritoneal CavityPeritonitisPhagocytosisPhagosomesSepsisToll-Like Receptor 4ConceptsToll-like receptor 4TLR4 WT micePeritoneal sepsisBacterial clearancePeritoneal cavityReceptor 4Functional Toll-like receptor 4Rate of phagocytosisMacrophage phagocytosisMutant Toll-like receptor 4Impaired bacterial clearanceTLR4 mutant miceSeptic courseIntraperitoneal injectionTLR4 mutantTherapeutic targetSepsis