2020
Stitching A Solution to the Addiction Epidemic: A Longitudinal Addiction Curricular Thread across Four Years of Medical Training
Muvvala SB, Schwartz ML, Petrakis I, O'Connor P, Tetrault JM. Stitching A Solution to the Addiction Epidemic: A Longitudinal Addiction Curricular Thread across Four Years of Medical Training. Substance Use & Addiction Journal 2020, 41: 475-479. PMID: 31951809, DOI: 10.1080/08897077.2019.1709606.Peer-Reviewed Original ResearchConceptsCurricular threadPractice-based learning activitiesMedical school curriculumComprehensive needs assessmentCurriculum goalsLearning activitiesSchool curriculumCurriculum developmentClerkship directorsDidactic activitiesEducational strategiesMedical schoolsKern modelClinical simulationMedical trainingCurriculumWorkshop exercisesNeeds assessmentWork forceClinical experienceSchoolsEducationPublic health impactImplementationInstitutions
2017
Partnering with Psychiatry to Close the Education Gap: An Approach to the Addiction Epidemic
Tetrault JM, Petrakis IL. Partnering with Psychiatry to Close the Education Gap: An Approach to the Addiction Epidemic. Journal Of General Internal Medicine 2017, 32: 1387-1389. PMID: 28766126, PMCID: PMC5698217, DOI: 10.1007/s11606-017-4140-9.Peer-Reviewed Original ResearchMeSH KeywordsBehavior, AddictiveClinical CompetenceCurriculumEducation, MedicalHumansInternal MedicinePsychiatrySubstance-Related DisordersUnited States
1999
CSF Monoamine Metabolite and Beta Endorphin Levels in Recently Detoxified Alcoholics and Healthy Controls: Prediction of Alcohol Cue‐Induced Craving?
Petrakis I, Trevisan L, D'Souza C, Gil R, Krasnicki S, Webb E, Heninger G, Cooney N, Krystal J. CSF Monoamine Metabolite and Beta Endorphin Levels in Recently Detoxified Alcoholics and Healthy Controls: Prediction of Alcohol Cue‐Induced Craving? Alcohol Clinical And Experimental Research 1999, 23: 1336-1341. PMID: 10470976, DOI: 10.1111/j.1530-0277.1999.tb04355.x.Peer-Reviewed Original ResearchConceptsAlcohol-dependent patientsHealthy controlsEndorphin levelsCSF levelsMonoamine metabolitesCSF measuresHealthy subjectsNorepinephrine metabolite MHPGLower CSF levelsBeta-endorphin levelsEarly-onset patientsCerebrospinal fluid levelsLate-onset patientsCentral neurotransmitter systemsCSF monoamine metabolitesDopamine metabolite HVAAlcohol cue exposureAlcohol-dependent individualsCue-Induced CravingAlcohol cue reactivityLumbar punctureMetabolite HVANeurotransmitter systemsMonoaminergic dysregulationMetabolite MHPG
1998
Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts
Petrakis I, Carroll K, Nich C, Gordon L, Kosten T, Rounsaville B. Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts. Drug And Alcohol Dependence 1998, 50: 221-226. PMID: 9649975, DOI: 10.1016/s0376-8716(98)00032-5.Peer-Reviewed Original ResearchConceptsCocaine useOpioid addictsMedication effectsDepressive symptomsSignificant decreaseEffectiveness of fluoxetineSelf-reported cocaine useDrug use outcomesSubsample of subjectsFluoxetine treatmentUrine toxicologySelf-reported useDepressive disorderSevere depressionHeroin useFluoxetineEffective agentUse outcomesDepressionPlaceboSignificant differencesTreatmentSymptomsAddictsMethadone