2015
Time Course and Predictors of Neurological Deterioration After Intracerebral Hemorrhage
Lord AS, Gilmore E, Choi HA, Mayer SA. Time Course and Predictors of Neurological Deterioration After Intracerebral Hemorrhage. Stroke 2015, 46: 647-652. PMID: 25657190, PMCID: PMC4739782, DOI: 10.1161/strokeaha.114.007704.Peer-Reviewed Original ResearchConceptsNeurological deteriorationIntracerebral hemorrhage volumeHematoma expansionInterventricular hemorrhageIntracerebral hemorrhageHemorrhage volumeAdmission Glasgow Coma ScaleEarly neurological deteriorationLate neurological deteriorationAcute neurological deteriorationRetrospective cohort studyHours of symptomsGlasgow Coma ScaleIntracerebral hemorrhage trialsTime coursePlacebo patientsCerebral edemaDevastating complicationRankin scoreCohort studyComa ScaleMedical complicationsPoor outcomeTomographic scanClinical evaluation
2012
Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis
Ong C, Gilmore E, Claassen J, Foreman B, Mayer SA. Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis. Neurocritical Care 2012, 17: 39-44. PMID: 22700361, DOI: 10.1007/s12028-012-9728-7.Peer-Reviewed Original ResearchConceptsRecovery of consciousnessComatose patientsElectrographic seizuresCEEG monitoringEpileptiform dischargesAdmission Glasgow Coma Scale scoreGlasgow Coma Scale scoreHypoxic-ischemic encephalopathyGlasgow Outcome ScaleTime of dischargeContinuous EEG monitoringNumber of AEDsPeriodic epileptiform dischargesComa prognosisResultsMean ageMedian durationCommon diagnosisIntracerebral hemorrhageFocal hypermetabolismNeuro-ICUSubarachnoid hemorrhageFrequent findingOutcome ScaleClinical significanceLikelihood of survival
2011
Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol
Choi HA, Ko SB, Presciutti M, Fernandez L, Carpenter AM, Lesch C, Gilmore E, Malhotra R, Mayer SA, Lee K, Claassen J, Schmidt JM, Badjatia N. Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol. Neurocritical Care 2011, 14: 389-394. PMID: 21210305, DOI: 10.1007/s12028-010-9474-7.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-2 Receptor AgonistsAdultAgedAnticonvulsantsConscious SedationCritical CareDexmedetomidineDose-Response Relationship, DrugFemaleFeverGlasgow Coma ScaleHeart ArrestHumansHypothermia, InducedIntensive Care UnitsIntracranial HypertensionMagnesium SulfateMaleMeperidineMiddle AgedMonitoring, PhysiologicNarcoticsNeuromuscular Nondepolarizing AgentsPropofolProspective StudiesShiveringVecuronium BromideConceptsPatient daysNeurological intensive care unitAnti-shivering agentsTherapeutic temperature modulationTotal patient daysPrevention of shiveringDoses of propofolIntensive care unitBaseline demographic informationNew clinical problemsInduced normothermiaMethodsAll patientsYounger patientsCare unitCumulative doseHigh riskClinical problemPatientsTemperature modulating devicesMore interventionsShiveringBaseline interventionDemographic informationFirst agentYoung men