2023
Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2017
Seizures and Status Epilepticus
Harris C, Gilmore E. Seizures and Status Epilepticus. 2017, 201-221. DOI: 10.1007/978-3-319-48669-7_12.Peer-Reviewed Original Research
2016
Status Epilepticus
Gilmore E, Nourollahzadeh E. Status Epilepticus. 2016, 23-33. DOI: 10.1007/978-3-319-33341-0_3.Peer-Reviewed Original ResearchManagement of seizuresStatus epilepticusSurgical intensive care unitLarge prospective epidemiologic studiesCommon neurological emergencyICU-related complicationsProspective epidemiologic studiesIntensive care unitOvert clinical manifestationsContinuous EEG monitoringMajority of seizuresNeurologic sequelaeCritical illnessSurgical ICUIll patientsSubstantial morbidityCare unitNeurological emergencyClinical manifestationsEarly recognitionMental statusWorse outcomesEpilepticusIctal activityEpidemiologic studies
2015
Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring
Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSevere sepsisEEG reactivityPeriodic dischargesLate seizuresSOFA scoreAPACHE IIFunctional outcomeContinuous sedationHigh riskLower riskMedical intensive care unitLong-term cognitive outcomesPresence of sedationAPACHE II scoreGood functional outcomeNonconvulsive status epilepticusIntensive care unitContinuous EEG monitoringAcute brain failureAcademic medical centerNew epilepsyII scoreClinical seizuresMedical ICU
2013
Assessment of Brain Death in the Neurocritical Care Unit
Hwang DY, Gilmore EJ, Greer DM. Assessment of Brain Death in the Neurocritical Care Unit. Neurosurgery Clinics Of North America 2013, 24: 469-482. PMID: 23809039, DOI: 10.1016/j.nec.2013.02.003.Peer-Reviewed Original Research
2011
Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol
Choi HA, Ko SB, Presciutti M, Fernandez L, Carpenter AM, Lesch C, Gilmore E, Malhotra R, Mayer SA, Lee K, Claassen J, Schmidt JM, Badjatia N. Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol. Neurocritical Care 2011, 14: 389-394. PMID: 21210305, DOI: 10.1007/s12028-010-9474-7.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-2 Receptor AgonistsAdultAgedAnticonvulsantsConscious SedationCritical CareDexmedetomidineDose-Response Relationship, DrugFemaleFeverGlasgow Coma ScaleHeart ArrestHumansHypothermia, InducedIntensive Care UnitsIntracranial HypertensionMagnesium SulfateMaleMeperidineMiddle AgedMonitoring, PhysiologicNarcoticsNeuromuscular Nondepolarizing AgentsPropofolProspective StudiesShiveringVecuronium BromideConceptsPatient daysNeurological intensive care unitAnti-shivering agentsTherapeutic temperature modulationTotal patient daysPrevention of shiveringDoses of propofolIntensive care unitBaseline demographic informationNew clinical problemsInduced normothermiaMethodsAll patientsYounger patientsCare unitCumulative doseHigh riskClinical problemPatientsTemperature modulating devicesMore interventionsShiveringBaseline interventionDemographic informationFirst agentYoung men