2024
Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey
Greige T, Tao B, Dangayach N, Gilmore E, O’Hana Nobleza C, Hinson H, Chou S, Jha R, Wahlster S, Gebrewold M, Lele A, Ong C. Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey. Neurocritical Care 2024, 1-15. PMID: 39085504, DOI: 10.1007/s12028-024-02077-0.Peer-Reviewed Original ResearchCerebral edemaPractice variationLife-threatening complicationsAttending physiciansFactors associated with practice variationFisher's exact testCritically ill patientsUniversity-affiliated centerAcute brain injuryMonitoring cerebral edemaOsmotic therapyExact testDecompressive hemicraniectomyBackgroundCerebral edemaRadiographic findingsTreatment strategiesIll patientsRadiographic indicatorsPractice patternsUniversity affiliationEdemaSociety web sitesLogistic regressionProvider preferencesPractice survey
2021
The Significance of LRDA With Bilateral Involvement Compared With GRDA on EEG in Critically Ill Patients
Fong M, Jadav R, Alzawahmah M, Hussein O, Gilmore E, Hirsch L. The Significance of LRDA With Bilateral Involvement Compared With GRDA on EEG in Critically Ill Patients. Journal Of Clinical Neurophysiology 2021, 40: 434-442. PMID: 37399042, DOI: 10.1097/wnp.0000000000000897.Peer-Reviewed Original ResearchConceptsLateralized rhythmic delta activityGroup of patientsRhythmic delta activityFocal abnormalitiesDelta activitySporadic epileptiform dischargesCritically Ill PatientsFocal electrographic seizuresComputed tomography scanClear etiologyIschemic strokeBilateral involvementIll patientsMetabolic encephalopathiesElectrographic seizuresImaging findingsFocal slowingCortical excitabilitySubdural hemorrhageTomography scanEpileptiform dischargesPatientsControl groupSeizuresContinuous EEG
2017
Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern
Cormier J, Maciel CB, Gilmore EJ. Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern. Seminars In Respiratory And Critical Care Medicine 2017, 38: 793-806. PMID: 29262437, DOI: 10.1055/s-0037-1607987.Peer-Reviewed Original ResearchConceptsNonconvulsive status epilepticusIctal-interictal continuumNonconvulsive seizuresEEG patternsSecondary brain injuryContinuous electroencephalography monitoringCritical care physiciansClear clinical significanceIIC patternsIll patientsStatus epilepticusCare physiciansCEEG monitoringElectroencephalography monitoringSeizure riskBrain injuryGuideline statementsClinical dilemmaClinical significanceNeuronal stressClinical approachDefinitive guidelinesElectroencephalography patternsPotential associationEarly detection
2016
Status Epilepticus
Gilmore E, Nourollahzadeh E. Status Epilepticus. 2016, 23-33. DOI: 10.1007/978-3-319-33341-0_3.Peer-Reviewed Original ResearchManagement of seizuresStatus epilepticusSurgical intensive care unitLarge prospective epidemiologic studiesCommon neurological emergencyICU-related complicationsProspective epidemiologic studiesIntensive care unitOvert clinical manifestationsContinuous EEG monitoringMajority of seizuresNeurologic sequelaeCritical illnessSurgical ICUIll patientsSubstantial morbidityCare unitNeurological emergencyClinical manifestationsEarly recognitionMental statusWorse outcomesEpilepticusIctal activityEpidemiologic studiesReview of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage
Gilmore EJ, Maciel CB, Hirsch LJ, Sheth KN. Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage. Stroke 2016, 47: 2666-2672. PMID: 27608820, DOI: 10.1161/strokeaha.116.012410.Peer-Reviewed Original ResearchUnderstanding and Managing the Ictal-Interictal Continuum in Neurocritical Care
Sivaraju A, Gilmore EJ. Understanding and Managing the Ictal-Interictal Continuum in Neurocritical Care. Current Treatment Options In Neurology 2016, 18: 8. PMID: 26874841, DOI: 10.1007/s11940-015-0391-0.Peer-Reviewed Original ResearchIctal-interictal continuumSpike-wave dischargesNeuronal injuryEEG patternsStatus epilepticusIctal-interictal continuum (IIC) patternsIntensive care unit settingClear clinical correlatePossible neuronal injuryBrain imaging findingsDepth electrode recordingsUse of anestheticsIntracranial pressure fluctuationsElectrographic improvementMultiple AEDsEnolase levelsIll patientsInterictal patternsAntiepileptic drugsElectrographic seizuresImaging findingsElectrographic patternsNeurocritical careClinical correlatesUnit setting
2015
Status epilepticus epidemiology—tracking a moving target
Gilmore EJ, Hirsch LJ. Status epilepticus epidemiology—tracking a moving target. Nature Reviews Neurology 2015, 11: 377-378. PMID: 26100743, DOI: 10.1038/nrneurol.2015.104.Peer-Reviewed Original Research