2019
Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage
Silverman A, Kodali S, Strander S, Gilmore EJ, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth KN, Petersen NH. Deviation From Personalized Blood Pressure Targets Is Associated With Worse Outcome After Subarachnoid Hemorrhage. Stroke 2019, 50: 2729-2737. PMID: 31495332, PMCID: PMC6756936, DOI: 10.1161/strokeaha.119.026282.Peer-Reviewed Original ResearchConceptsLimits of autoregulationAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageFunctional outcomeArterial pressureIntracranial pressureBP targetsWorse outcomesPercent timeBlood pressure targetsBlood pressure managementMean arterial pressureModified Rankin ScalePotential neuroprotective strategiesWorse functional outcomePoor functional outcomeCerebral blood flowMultivariate logistic regressionTotal monitoring periodAutoregulatory indexPressure targetsCerebral ischemiaNeuroprotective strategiesRankin ScaleCerebral autoregulation
2016
Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage
Zafar SF, Westover MB, Gaspard N, Gilmore EJ, Foreman BP, O'Connor KL, Rosenthal ES. Interrater Agreement for Consensus Definitions of Delayed Ischemic Events After Aneurysmal Subarachnoid Hemorrhage. Journal Of Clinical Neurophysiology 2016, 33: 235-240. PMID: 27258447, PMCID: PMC4894325, DOI: 10.1097/wnp.0000000000000276.Peer-Reviewed Original ResearchConceptsDelayed ischemic eventsCerebral infarctionNeurologic declineSubarachnoid hemorrhageConsensus definitionIschemic eventsCerebral ischemiaClinical trialsInterrater agreementPerfect overall agreementRadiographic cerebral infarctionPercent of patientsAneurysmal subarachnoid hemorrhageFuture large-scale studiesSuccessful clinical trialsMotor scoresMotor declineOutcome studiesInfarctionIschemiaType 1HemorrhageCT imagingLarge-scale studiesMRI techniques