2006
Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity
Huleatt JW, Jacobs AR, Tang J, Desai P, Kopp EB, Huang Y, Song L, Nakaar V, Powell TJ. Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine 2006, 25: 763-775. PMID: 16968658, DOI: 10.1016/j.vaccine.2006.08.013.Peer-Reviewed Original ResearchConceptsCD8 T cell responsesT cell responsesAntigen-specific responsesCell responsesRecombinant fusion proteinAntigen fusion proteinProtective CD8 T cell responsesAntigen-specific CD8 T-cell responsesPotent antigen-specific responsesToll-like receptor ligandsToll-like receptor (TLR) familyComplete Freund's adjuvantDay of immunizationB cell responsesTLR5 ligand flagellinImmunization of miceRecombinant protein vaccineVirulent L. monocytogenesSupplemental adjuvantsProtective immunityTLR ligandsFreund's adjuvantHumoral immunityProtein vaccineEnhanced immunogenicity
1994
Inhibition of NF-κB by Sodium Salicylate and Aspirin
Kopp E, Ghosh S. Inhibition of NF-κB by Sodium Salicylate and Aspirin. Science 1994, 265: 956-959. PMID: 8052854, DOI: 10.1126/science.8052854.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAspirinCell LineEnhancer Elements, GeneticGene ExpressionGenes, ReporterHIV Long Terminal RepeatHIV-1HumansImmunoglobulin kappa-ChainsLipopolysaccharidesMiceNF-kappa BPhosphorylationPromoter Regions, GeneticProtein BiosynthesisProto-Oncogene ProteinsSodium SalicylateT-LymphocytesTranscription Factor RelBTranscription FactorsTransfectionTumor Cells, CulturedConceptsNF-kappa BInterleukin-1Anti-inflammatory drug sodium salicylateHuman immunodeficiency virus long terminal repeatNF-kappa B inhibitorSodium salicylateMechanism of actionLong terminal repeatIL-6T cellsNF-κBAspirinAdhesion moleculesVirus long terminal repeatB inhibitorViral genesInhibitionDependent transcriptionInducible expressionSalicylateInflammationTranscription factorsInfectionTerminal repeat
1987
Differential collagen biosynthesis by human neuroblastoma cell variants.
DeClerck Y, Bomann E, Spengler B, Biedler J. Differential collagen biosynthesis by human neuroblastoma cell variants. Cancer Research 1987, 47: 6505-10. PMID: 2445473.Peer-Reviewed Original Research