2023
Diagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder
Zakiniaeiz Y, Lacadie C, Macdonald-Gagnon G, DeVito E, Potenza M. Diagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder. Drug And Alcohol Dependence 2023, 251: 110962. PMID: 37716288, PMCID: PMC10557108, DOI: 10.1016/j.drugalcdep.2023.110962.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingCocaineFemaleHumansMagnetic Resonance ImagingMaleSex CharacteristicsStroop TestSubstance-Related DisordersConceptsCocaine use disorderCognitive controlStroop performanceIntrinsic connectivityStroop task performanceFMRI Stroop taskDiagnostic groupsUse disordersDiagnostic group differencesMain effectHealthy comparison subjectsStroop effectStroop taskBehavioral resultsTask performanceFrontal gyrusIntrinsic connectivity distributionPrefrontal cortexAuditory areasGroup differencesBrain connectivityCingulate gyrusStroopBehavioral differencesHC group
2021
Longitudinal changes in network engagement during cognitive control in cocaine use disorder
Morie KP, DeVito EE, Potenza MN, Worhunsky PD. Longitudinal changes in network engagement during cognitive control in cocaine use disorder. Drug And Alcohol Dependence 2021, 229: 109151. PMID: 34753083, PMCID: PMC8671376, DOI: 10.1016/j.drugalcdep.2021.109151.Peer-Reviewed Original ResearchMeSH KeywordsBrainCocaineCocaine-Related DisordersCognitionHumansMagnetic Resonance ImagingSubstance-Related DisordersConceptsCocaine use disorderCognitive controlRight frontoparietal networkNetwork engagementUse disordersPoor cognitive controlFMRI Stroop taskCocaine use behaviorFunctional neural networksStroop taskBrain mechanismsIndependent component analysisCocaine useNeural systemsLongitudinal effectsFunctional networksGreater engagement
2018
Structural correlates of cognitive impairment in normal pressure hydrocephalus
Peterson KA, Mole TB, Keong NCH, DeVito EE, Savulich G, Pickard JD, Sahakian BJ. Structural correlates of cognitive impairment in normal pressure hydrocephalus. Acta Neurologica Scandinavica 2018, 139: 305-312. PMID: 30428124, PMCID: PMC6492129, DOI: 10.1111/ane.13052.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainCognitive DysfunctionFemaleHumansHydrocephalus, Normal PressureMagnetic Resonance ImagingMaleMiddle AgedConceptsNormal pressure hydrocephalusNPH patientsNeuropsychiatric symptomsPressure hydrocephalusNeuropsychiatric measuresNeuropsychological testsStructure volumesStriatal volume lossDeep gray matter structuresMeasures of apathySubcortical deep gray matter structuresT1-weighted magnetic resonanceGray matter structuresNAcc volumeSmaller caudateNeuropsychiatric changesHealthy controlsPathological basisNPH groupCaudate nucleusNucleus accumbensCaudate volumePatientsSubcortical regionsCognitive impairmentCan neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research
Moningka H, Lichenstein S, Worhunsky PD, DeVito EE, Scheinost D, Yip SW. Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research. Neuropsychopharmacology 2018, 44: 259-273. PMID: 30283002, PMCID: PMC6300537, DOI: 10.1038/s41386-018-0232-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBrainHumansMagnetic Resonance ImagingNeuroimagingOpioid-Related DisordersResearch DesignConceptsOpioid use disorderOpioid epidemicTreatment responseTask-based fMRI paradigmsUrgent public health problemMedication-assisted treatmentPrescription opioid usersCurrent opioid epidemicPublic health problemEvidence-based treatmentsPaucity of literatureHeroin cuesOpioid medicationsRelapse rateOpioid systemOpioid usersFuture neuroimaging studiesSignificant individual variabilityHealthcare costsWithdrawal effectsHealthy individualsHealth problemsSystematic reviewExtended abstinenceNeuroimaging studiesfMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals
DeVito EE, Kober H, Carroll KM, Potenza MN. fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals. Addictive Behaviors 2018, 89: 10-14. PMID: 30240978, PMCID: PMC6374034, DOI: 10.1016/j.addbeh.2018.09.005.Peer-Reviewed Original ResearchConceptsCocaine use disorderStroop effectBehavioral treatmentComputer-based cognitive behavioral therapyColor-word Stroop taskCognitive neuroscience methodsCognitive behavioral therapyCocaine-dependent individualsCocaine abstinenceCognitive controlStroop taskNeuroscience methodsMethadone-maintained individualsTreatment abstinenceLingual gyrusStroopCingulate gyrusUse disordersCocaine usersTreatment mechanismsAbstinenceBetter treatment outcomesPreliminary findingsGyrusParticipants
2017
Functional Neural Changes Following Behavioral Therapies and Disulfiram for Cocaine Dependence
DeVito EE, Dong G, Kober H, Xu J, Carroll KM, Potenza MN. Functional Neural Changes Following Behavioral Therapies and Disulfiram for Cocaine Dependence. Psychology Of Addictive Behaviors 2017, 31: 534-547. PMID: 28714728, PMCID: PMC5548432, DOI: 10.1037/adb0000298.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContingency managementPrecentral gyrusNeural activityFrontal gyrusWhole-brain correlation analysesRandomized clinical trialsSample overallBeginning of treatmentForm of treatmentMedial frontal gyrusInferior parietal lobuleCocaine use disorderDifferent treatment componentsMedication daysClinical trialsTreatment outcomesUse disordersTreatment relateFunctional changesParietal lobuleGyrusTreatment componentsGreater reductionTreatment
2016
Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response
Yip SW, DeVito EE, Kober H, Worhunsky PD, Carroll KM, Potenza MN. Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response. Drug And Alcohol Dependence 2016, 166: 134-142. PMID: 27430401, PMCID: PMC5082418, DOI: 10.1016/j.drugalcdep.2016.07.006.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentCocaine-dependent individualsBOLD responseCocaine dependenceSignificant public health problemMethadone-maintained individualsMethadone-maintained populationsMethadone-maintained patientsElevated relapse ratesPublic health problemCocaine-negative urinesCocaine-dependent patientsAnticipatory reward processingPosterior cingulate cortexLoss processingDuration of abstinenceDorsolateral prefrontal cortexCD patientsRelapse rateWhole-brain ANOVAInferior frontal gyrusTreatment outcomesRight caudateHealthy comparison participantsPatients
2014
Hippocampal volume mediates the relationship between measures of pre-treatment cocaine use and within-treatment cocaine abstinence
Xu J, Kober H, Wang X, DeVito EE, Carroll KM, Potenza MN. Hippocampal volume mediates the relationship between measures of pre-treatment cocaine use and within-treatment cocaine abstinence. Drug And Alcohol Dependence 2014, 143: 74-80. PMID: 25115748, PMCID: PMC4165405, DOI: 10.1016/j.drugalcdep.2014.07.007.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmygdalaBehavior TherapyCase-Control StudiesCocaine-Related DisordersFemaleHippocampusHumansMagnetic Resonance ImagingMaleNeuroimagingOrgan SizeTreatment OutcomeYoung AdultConceptsCocaine-dependent patientsHippocampal volumeTreatment outcomesCocaine useCocaine use severityCocaine-negative urine samplesGreater hippocampal volumePoor treatment outcomesPatient groupTreatment trialsContinuous abstinenceHigh-resolution magnetic resonance brain imagesTreatment responseIndividualized treatmentHealthy comparison individualsPatientsCocaine abstinenceCocaine dependenceBehavioral therapyCocaine-related cuesMore daysUrine samplesContingency managementSignificant differencesSignificant correlationPretreatment measures of brain structure and reward-processing brain function in cannabis dependence: An exploratory study of relationships with abstinence during behavioral treatment 1
Yip SW, DeVito EE, Kober H, Worhunsky PD, Carroll KM, Potenza MN. Pretreatment measures of brain structure and reward-processing brain function in cannabis dependence: An exploratory study of relationships with abstinence during behavioral treatment 1. Drug And Alcohol Dependence 2014, 140: 33-41. PMID: 24793365, PMCID: PMC4057888, DOI: 10.1016/j.drugalcdep.2014.03.031.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainCognitive Behavioral TherapyFemaleHumansMagnetic Resonance ImagingMaleMarijuana AbusePsychomotor PerformanceReaction TimeRewardSubstance Withdrawal SyndromeYoung AdultConceptsCannabis-dependent participantsMagnetic resonance imagingCannabis dependenceHC participantsTreatment responseConsecutive abstinenceHealthy comparison menBilateral putamen volumesCannabis-dependent individualsSuccessful treatment outcomeEfficacy of therapeuticsDays of abstinenceVentral striatal activationClinical trialsStriatal functionTreatment outcomesMRI scanningComparison menPutamen volumeResonance imagingBehavioral treatmentBiological markersBrain functionBrain structuresAbstinenceCannabis Abstinence During Treatment and One-Year Follow-Up: Relationship to Neural Activity in Men
Kober H, DeVito EE, DeLeone CM, Carroll KM, Potenza MN. Cannabis Abstinence During Treatment and One-Year Follow-Up: Relationship to Neural Activity in Men. Neuropsychopharmacology 2014, 39: 2288-2298. PMID: 24705568, PMCID: PMC4138744, DOI: 10.1038/npp.2014.82.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain MappingCannabisFollow-Up StudiesHumansIllicit DrugsMagnetic Resonance ImagingMaleMarijuana AbuseReaction TimeSelf ReportStroop TestTreatment OutcomeConceptsCannabis-dependent groupHealthy comparison groupNeural activityCognitive controlLess cannabisDorsal anterior cingulate cortexCognitive control taskCognitive behavioral therapyTreatment development effortsCannabis-dependent individualsAnterior cingulate cortexAddiction-related processesFMRI taskSubstance use disordersCannabis abstinenceCingulate cortexVentral striatumCannabis dependenceCannabis useContingency managementLess abstinenceAbstinenceHealthy individualsCannabisGreater activity
2013
A preliminary investigation of Stroop-related intrinsic connectivity in cocaine dependence: associations with treatment outcomes
Mitchell MR, Balodis IM, DeVito EE, Lacadie CM, Yeston J, Scheinost D, Constable RT, Carroll KM, Potenza MN. A preliminary investigation of Stroop-related intrinsic connectivity in cocaine dependence: associations with treatment outcomes. The American Journal Of Drug And Alcohol Abuse 2013, 39: 392-402. PMID: 24200209, PMCID: PMC3827911, DOI: 10.3109/00952990.2013.841711.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainCase-Control StudiesCocaine-Related DisordersCognitionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMotivationStroop TestTreatment OutcomeConceptsTreatment outcomesComparison subjectsCocaine-dependent patientsIntrinsic connectivityCocaine dependenceSubstantia nigraVentral striatumTreatment-seeking cocaine-dependent patientsHealthy comparison subjectsPotential treatment targetGreater intrinsic connectivityRegional brain activationCocaine-dependent groupIntrinsic connectivity analysesNon-addicted individualsBasal gangliaInferior frontal gyrusCocaine-dependent individualsTreatment targetsFMRI Stroop taskSubcortical regionsCocaine abstinenceBrain regionsAnterior insulaFrontal gyrus
2012
Impaired inhibitory control in ‘internet addiction disorder’: A functional magnetic resonance imaging study
Dong G, DeVito EE, Du X, Cui Z. Impaired inhibitory control in ‘internet addiction disorder’: A functional magnetic resonance imaging study. Psychiatry Research 2012, 203: 153-158. PMID: 22892351, PMCID: PMC3650485, DOI: 10.1016/j.pscychresns.2012.02.001.Peer-Reviewed Original ResearchConceptsIAD groupMagnetic resonance imaging studyPrevalent mental health concernAddiction disordersResonance imaging studyFunctional magnetic resonance imaging studyPosterior cingulate cortexMental health concernsImpaired inhibitory controlHealthy controlsHealthy peersInternet addiction disorderCingulate cortexImaging studiesHealth concernDisordersNeurobiological underpinningsInhibitory controlResponse inhibitionNeural correlatesResponse inhibition processesPotential heterogeneityPresent studyGroupMemantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism
Jamadar S, DeVito EE, Jiantonio RE, Meda SA, Stevens MC, Potenza MN, Krystal JH, Pearlson GD. Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology 2012, 222: 129-140. PMID: 22311382, PMCID: PMC3674025, DOI: 10.1007/s00213-011-2628-2.Peer-Reviewed Original ResearchConceptsNMDA receptor antagonistFamily historyFHN subjectsReceptor antagonistFHP subjectsN-methyl-D-aspartate receptor functionReceptor functionIdentical-appearing placeboEffects of memantineFMRI activityNMDA receptor functionCorrect rejectsSingle doseMemantineGo/No-Go taskSeparate daysTemporal regionsCingulate activation
2011
A preliminary study of the neural effects of behavioral therapy for substance use disorders
DeVito EE, Worhunsky PD, Carroll KM, Rounsaville BJ, Kober H, Potenza MN. A preliminary study of the neural effects of behavioral therapy for substance use disorders. Drug And Alcohol Dependence 2011, 122: 228-235. PMID: 22041256, PMCID: PMC3296894, DOI: 10.1016/j.drugalcdep.2011.10.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBehavior TherapyBrainFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsStroop TestSubstance-Related DisordersTreatment OutcomeYoung AdultConceptsComputer-assisted cognitive behavioral therapyBehavioral therapySubstance use disordersInferior frontal gyrusCognitive behavioral therapyMaintenance of addictionUse disordersSubstance use outcomesCognitive controlFrontal gyrusTest-retest conditionsNeural effectsComponent of treatmentAnterior cingulateImpulse controlNeural systemsSame taskUse outcomesBOLD signalSubstance useSubstance abuseStroopComparison groupRandomized clinical trialsHealthy controls
2007
Caudate structural abnormalities in idiopathic normal pressure hydrocephalus
DeVito E, Salmond C, Owler B, Sahakian B, Pickard J. Caudate structural abnormalities in idiopathic normal pressure hydrocephalus. Acta Neurologica Scandinavica 2007, 116: 328-332. PMID: 17922726, DOI: 10.1111/j.1600-0404.2007.00906.x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrophyBasal Ganglia DiseasesCaudate NucleusCerebrospinal Fluid PressureCorpus CallosumDisease ProgressionFemaleHumansHydrocephalus, Normal PressureImage Processing, Computer-AssistedIntracranial HypertensionLateral VentriclesMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsConceptsNormal pressure hydrocephalusPressure hydrocephalusIdiopathic normal pressure hydrocephalusManual volumetric analysisVoxel-based morphometric analysisCaudate nucleus volumeStructural volumetric changesINPH patientsReversible dementiaINPH groupHealthy controlsCaudate nucleusStructural abnormalitiesCognitive deficitsVolumetric analysisNucleus volumeHydrocephalusRegion of interestROI measurementsINPHMorphometric analysisAffective changes