2013
Multimodality Imaging Approach for Serial Assessment of Regional Changes in Lower Extremity Arteriogenesis and Tissue Perfusion in a Porcine Model of Peripheral Arterial Disease
Stacy MR, Yu da Y, Maxfield MW, Jaba IM, Jozwik BP, Zhuang ZW, Lin BA, Hawley CL, Caracciolo CM, Pal P, Tirziu D, Sampath S, Sinusas AJ. Multimodality Imaging Approach for Serial Assessment of Regional Changes in Lower Extremity Arteriogenesis and Tissue Perfusion in a Porcine Model of Peripheral Arterial Disease. Circulation Cardiovascular Imaging 2013, 7: 92-99. PMID: 24170237, PMCID: PMC3929970, DOI: 10.1161/circimaging.113.000884.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArteriesCapillariesCollateral CirculationDisease Models, AnimalLower ExtremityMaleMultimodal ImagingNeovascularization, PhysiologicPerfusion ImagingPeripheral Arterial DiseasePredictive Value of TestsRegional Blood FlowReproducibility of ResultsSwineTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedConceptsPeripheral arterial diseaseSPECT/CT imagingArterial diseaseWeeks postocclusionProximal musclesCT imagingCapillary densityTissue perfusionPorcine modelLower extremity perfusionSingle photon emission tomographyFemoral artery occlusionMultimodality Imaging ApproachPhoton emission tomographyGamma countingIschemic calfNonischemic hindlimbsExtremity perfusionArtery occlusionLimb ischemiaMuscle perfusionSerial assessmentSerial changesCT angiographySPECT perfusion
1993
Pathobiochemical Changes of the Arterial Wall at the Inception of Atherosclerosis
Simionescu N, Sima A, Dobrian A, Tirziu D, Simionescu M. Pathobiochemical Changes of the Arterial Wall at the Inception of Atherosclerosis. Current Topics In Pathology 1993, 87: 1-45. PMID: 8125021, DOI: 10.1007/978-3-642-76849-1_1.Peer-Reviewed Original ResearchConceptsLow-density lipoproteinPotential therapeutic implicationsCerebral infarctionSerum cholesterolLipid infiltrationLDL metabolismPathogenic factorsPathobiochemical changesTherapeutic implicationsAtherosclerosisLDL receptorArterial wallArtery wallCardiovascular researchMolecular mechanismsMultiplicity of factorsCellular eventsLines of investigationInfarctionAtherogenesisPathogenesis