2022
Chronic pain precedes disrupted eating behavior in low-back pain patients
Lin Y, De Araujo I, Stanley G, Small D, Geha P. Chronic pain precedes disrupted eating behavior in low-back pain patients. PLOS ONE 2022, 17: e0263527. PMID: 35143525, PMCID: PMC8830732, DOI: 10.1371/journal.pone.0263527.Peer-Reviewed Original ResearchConceptsLow back pain patientsChronic low back pain patientsFat-rich foodsPain patientsChronic painCLBP patientsSBP patientsNucleus accumbensBack pain patientsChronic pain patientsHealthy control subjectsNucleus accumbens volumePain chronificationFat ingestionHedonic feedingPatient populationAccumbens volumeControl subjectsLimbic brainPainEarly coursePatientsBehavioral alterationsHedonic perceptionNeurological standpoint
2012
Altered hypothalamic response to food in smokers 1 , 2 , 3
Geha PY, Aschenbrenner K, Felsted J, O'Malley SS, Small DM. Altered hypothalamic response to food in smokers 1 , 2 , 3. American Journal Of Clinical Nutrition 2012, 97: 15-22. PMID: 23235196, PMCID: PMC3522134, DOI: 10.3945/ajcn.112.043307.Peer-Reviewed Original ResearchConceptsWeight changeBrain responsesFunctional MRILong-term weight changeAltered brain responsesTasteless control solutionMilk shakeEnergy-dense foodsGroup of ageSmoking statusSmoking cessationSmoking influencesHypothalamic responseNonsmokersSmokersVentral striatumWeight gainBMIHypothalamusGreater responseResponseFoodStudy 1ThalamusGroup
2005
Gustatory agnosia
Small DM, Bernasconi N, Bernasconi A, Sziklas V, Jones-Gotman M. Gustatory agnosia. Neurology 2005, 64: 311-317. PMID: 15668430, DOI: 10.1212/01.wnl.0000149515.77718.35.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgnosiaAmygdalaAnorexiaAtrophyCerebral CortexElectrodes, ImplantedElectroencephalographyEpilepsy, Temporal LobeFemaleFollow-Up StudiesFood PreferencesHippocampusHumansMagnetic Resonance ImagingMeningoencephalitisNeuropsychological TestsOlfaction DisordersPositron-Emission TomographyPostoperative ComplicationsTasteTaste ThresholdTemporal LobeConceptsMedial temporal lobeTemporal lobeSurgical treatmentLeft medial temporal lobeAnteromedial temporal lobeFunctional neuroimaging studiesBilateral atrophyIntractable epilepsyComplete atrophyPreoperative MRIGustatory functionLeft amygdalaLeft insulaChemosensory evaluationNeuroimaging studiesTaste abilityPatientsAtrophyAmygdalaAversive tasteLobeRecognition thresholdAgnosiaTreatmentTaste quality