2015
Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers
van Kooten MJ, Veldhuizen MG, de Araujo IE, O'Malley SS, Small DM. Fatty acid amide supplementation decreases impulsivity in young adult heavy drinkers. Physiology & Behavior 2015, 155: 131-140. PMID: 26656766, PMCID: PMC4718847, DOI: 10.1016/j.physbeh.2015.11.032.Peer-Reviewed Original ResearchConceptsGo/No-Go taskHeavy drinkersStriatal extracellular dopamine levelsVagal afferent signalingExtracellular dopamine levelsHeavy drinking young adultsAlcohol intakeAdult heavy drinkersSupplementation regimenAfferent signalingYoung adult heavy drinkersDopamine levelsSelf-report questionnairesDecrease impulsivityTherapeutic potentialDietary supplementsIntragastric infusionAlcohol useYoung adultsFatty acid amidesPlaceboPreliminary evidenceBehavioral tasksImpulsive respondingImpulsive behavior
2009
Neural correlates of evaluative compared with passive tasting
Bender G, Veldhuizen MG, Meltzer JA, Gitelman DR, Small DM. Neural correlates of evaluative compared with passive tasting. European Journal Of Neuroscience 2009, 30: 327-338. PMID: 19614981, PMCID: PMC2776645, DOI: 10.1111/j.1460-9568.2009.06819.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleHumansMagnetic Resonance ImagingMaleNerve NetPilot ProjectsPsychomotor PerformanceTasteYoung AdultConceptsLateral orbitofrontal cortexOrbitofrontal cortexPrimary taste cortexLeft lateral orbitofrontal cortexFunctional magnetic resonanceTasteless solutionMaximal responseTaste cortexFunction of taskCortical representationGustatory informationAnterior insulaVentral regionNeural responsesPreferential connectivityAmygdalaNeural correlatesCortexInsulaNeural encodingSubjectsStimulus presenceMagnetic resonanceResponseEarly relay
2005
Monetary Incentives Enhance Processing in Brain Regions Mediating Top-down Control of Attention
Small DM, Gitelman D, Simmons K, Bloise SM, Parrish T, Mesulam M. Monetary Incentives Enhance Processing in Brain Regions Mediating Top-down Control of Attention. Cerebral Cortex 2005, 15: 1855-1865. PMID: 15746002, DOI: 10.1093/cercor/bhi063.Peer-Reviewed Original ResearchConceptsSpatial expectancyVisual spatial attentionNon-directional cuesCurrent behavioral goalsControl of attentionTarget detection taskFaster reaction timesInferior parietal lobulePosterior cingulate cortexDifferent incentive conditionsValid cuesCentral cuesSpatial attentionMotivational mechanismsNeural processingMotivational incentivesUnimodal cortexBehavioral goalsLimbic mechanismsParietal lobuleAttention networkDetection taskCingulate cortexRelationship of activationIncentive conditions
2003
The posterior cingulate and medial prefrontal cortex mediate the anticipatory allocation of spatial attention
Small DM, Gitelman DR, Gregory MD, Nobre AC, Parrish TB, Mesulam M. The posterior cingulate and medial prefrontal cortex mediate the anticipatory allocation of spatial attention. NeuroImage 2003, 18: 633-641. PMID: 12667840, DOI: 10.1016/s1053-8119(02)00012-5.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexCue benefitPrefrontal cortexPosterior cingulateAttention-related areasNeutral cuesCentral cuesSpatial attentionSpatial expectancyFMRI scanningIrrelevant locationsMotivational valenceGreater activationParietal cortexBrain regionsCuesPeripheral targetsReaction timeCingulateCortexDistractibilityExpectancySignificant eventsAttentionValence