2023
Connectome-based predictive modeling shows sex differences in brain-based predictors of memory performance
Ju S, Horien C, Shen X, Abuwarda H, Trainer A, Constable R, Fredericks C. Connectome-based predictive modeling shows sex differences in brain-based predictors of memory performance. Frontiers In Dementia 2023, 2: 1126016. PMID: 39082002, PMCID: PMC11285565, DOI: 10.3389/frdem.2023.1126016.Peer-Reviewed Original ResearchDefault mode networkConnectome-based predictive modelingMemory performanceMemory taskMemory scoresShort-term memory performanceBrain-based predictorsShort-term memoryPosterior default mode networkAmnestic Alzheimer's diseaseRecollective memoryDMN activityMode networkVisual networkPast researchSex-specific modelsVisual circuitryAlzheimer's diseaseSex differencesMemoryDifferent circuitryTaskElevated riskMachine learning approachesNetwork activity
2018
Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar?
Fredericks CA, Brown JA, Deng J, Kramer A, Ossenkoppele R, Rankin K, Kramer JH, Miller BL, Rabinovici GD, Seeley WW. Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar? NeuroImage Clinical 2018, 21: 101628. PMID: 30528957, PMCID: PMC6411779, DOI: 10.1016/j.nicl.2018.101628.Peer-Reviewed Original ResearchConceptsPosterior cortical atrophyVisuospatial networkAlzheimer's diseaseClinical featuresCortical atrophyPulvinar nucleusSN connectivityConnectivity changesPulvinar thalamic nucleiPatients' clinical featuresAmnestic Alzheimer's diseaseMedial pulvinar nucleusLateral pulvinar nucleusDefault mode network connectivitySalience network connectivityMore depressive symptomsMode network connectivityStandardized neuropsychological batteryTask-free fMRIIntrinsic connectivity networksDirect anatomical connectionsVisuospatial symptomsConnectivity increasesBrain atrophyPCa patients