2000
Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system
Eichmann A, Yuan L, Bréant C, Alitalo K, Koskinen P. Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system. Oncogene 2000, 19: 1215-1224. PMID: 10713710, DOI: 10.1038/sj.onc.1203355.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAmino Acid SequenceAnimalsCloning, MolecularEctodermEmbryo, NonmammalianEmbryonic and Fetal DevelopmentEmbryonic DevelopmentGene Expression Regulation, DevelopmentalHematopoiesisHumansMiceMolecular Sequence DataNervous SystemOrgan SpecificityProtein Serine-Threonine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-pim-1QuailRatsTranscription, GeneticConceptsExpression patternsSerine/threonine kinaseDeduced amino acid sequenceDynamic expression patternHematopoietic systemPim-1Amino acid sequencePim family kinasesEarly developmental stagesFunctional redundancyThreonine kinaseFamily kinasesEmbryonic developmentStrong homologyNovel functionAcid sequenceExpression sitesPIM genesAvian embryosDevelopmental expressionDevelopmental stagesPIM familyPIM kinasesCDNAKinase
1998
Segregation of the embryonic vascular and hemopoietic systems
Eichmann A, Corbel C, Le Douarin N. Segregation of the embryonic vascular and hemopoietic systems. Biochemistry And Cell Biology 1998, 76: 939-946. PMID: 10392707, DOI: 10.1139/o98-106.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCell DifferentiationChick EmbryoEmbryo, NonmammalianEndothelial Growth FactorsEndothelium, VascularHematopoietic Stem CellsLymphokinesMesodermMiceModels, CardiovascularQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsEndothelial precursor cellsAvian embryosPrecursor cellsVEGF receptor VEGFR2Primary vascular systemEndothelial cellsGastrulation stageGrowth factorDevelopmental biologyVertebrate classesSpecific growth factorsVascular endothelial growth factorAngiogenic vascular endothelial growth factorMouse embryosMolecular mechanismsCognate receptorsSubsequent assemblyHemopoietic cellsEmbryosReceptor VEGFR2Hemopoietic systemCulture experimentsVEGFR2CellsSignificant insights
1997
Expression of the avian VEGF receptor homologues Quek1 and Quek2 in blood-vascular and lymphatic endothelial and non-endothelial cells during quail embryonic development
Wilting J, Eichmann A, Christ B. Expression of the avian VEGF receptor homologues Quek1 and Quek2 in blood-vascular and lymphatic endothelial and non-endothelial cells during quail embryonic development. Cell And Tissue Research 1997, 288: 207-223. PMID: 9082957, DOI: 10.1007/s004410050807.Peer-Reviewed Original Research
1993
Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development
Eichmann A, Marcelle C, Bréant C, Le Douarin N. Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development. Cells And Development 1993, 42: 33-48. PMID: 8396413, DOI: 10.1016/0925-4773(93)90096-g.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChick EmbryoCloning, MolecularEmbryo, NonmammalianEndothelium, VascularMolecular Sequence DataProtein-Tyrosine KinasesQuailReceptor Protein-Tyrosine KinasesReceptors, MitogenReceptors, NeurotransmitterReceptors, Vascular Endothelial Growth FactorSequence Homology, Nucleic AcidVascular Endothelial Growth Factor Receptor-2ConceptsExpression patternsOnset of gastrulationAvian embryonic developmentEndothelial cellsEarly endothelial cellsMonoclonal antibody QH1Human genesEmbryonic developmentEmbryonic day 9Vascular endothelial growth factorHigh homologyHematopoietic lineagesAvian embryosPartial cloningSitu hybridizationReceptor moleculesGastrulationPutative precursorEndothelial cell mitogen vascular endothelial growth factorFlk-1GenesEmbryosGrowth factorQH1VEGF receptors
1992
Molecular cloning of a family of protein kinase genes expressed in the avian embryo.
Marcelle C, Eichmann A. Molecular cloning of a family of protein kinase genes expressed in the avian embryo. Oncogene 1992, 7: 2479-87. PMID: 1281306.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBlastocystChick EmbryoChickensCloning, MolecularEmbryo, NonmammalianGene ExpressionMolecular Sequence DataMultigene FamilyNervous SystemNeural CrestOligodeoxyribonucleotidesOrgan SpecificityPhylogenyPoly APolymerase Chain ReactionProtein KinasesProtein-Tyrosine KinasesQuailReceptors, Cell SurfaceRNARNA, MessengerSequence Homology, Amino AcidSequence Homology, Nucleic AcidTranscription, GeneticConceptsReceptor tyrosine kinasesPKS genesGrowth factor receptorPutative receptor tyrosine kinaseTyrosine kinaseSerine/threonine kinaseProtein kinase sequencesEarly vertebrate developmentProtein kinase geneCytosolic tyrosine kinasesFactor receptorFibroblast growth factor receptorGrowth factor receptor tyrosine kinasePlatelet-derived growth factor receptor alphaGrowth factor receptor alphaNorthern blot analysisPattern of expressionReceptor-like moleculesVertebrate developmentInsulin-like growth factor type I receptorKinase sequencesType I receptorThreonine kinaseMore transcriptsAvian homolog