2023
Receipt of Smoking Cessation Medications Among People With and Without Human Immunodeficiency Virus in the Veterans Aging Cohort Study (2003–2018)
Shahrir S, Crothers K, McGinnis K, Chan K, Baeten J, Wilson S, Butt A, Pisani M, Baldassarri S, Justice A, Williams E. Receipt of Smoking Cessation Medications Among People With and Without Human Immunodeficiency Virus in the Veterans Aging Cohort Study (2003–2018). Open Forum Infectious Diseases 2023, 10: ofad089. PMID: 36968969, PMCID: PMC10034589, DOI: 10.1093/ofid/ofad089.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyAging Cohort StudyHuman immunodeficiency virusCessation medicationsCohort studyCurrent smokersCurrent smokingHIV statusImmunodeficiency virusRelative riskHuman immunodeficiency virus statusSmoking cessation medicationsNicotine replacement therapyRates of receiptDangers of smokingOutpatient prescriptionsReplacement therapyPharmacy dataVirus statusTobacco useAnnual rateMedicationsSmokingPWHStatistical difference
2020
Validation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV
Rodriguez-Barradas MC, McGinnis KA, Akgün K, Tate JP, Brown ST, Butt AA, Fine M, Goetz MB, Graber CJ, Huang L, Rimland D, Justice A, Crothers K. Validation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV. Pneumonia 2020, 12: 6. PMID: 32724760, PMCID: PMC7382068, DOI: 10.1186/s41479-020-00068-1.Peer-Reviewed Original ResearchICD-9 codesPharmacy dataUninfected groupEHR algorithmPrimary positionOverall positive predictive valueResultsFive hundred fortyGroup of patientsElectronic health record dataICD-9 diagnosisHealth record dataPositive predictive valueCode-based algorithmsElectronic health recordsCAP hospitalizationsCOPD exacerbationsMicrobiologic workupOverall PPVUninfected patientsAspiration pneumoniaPneumonia hospitalizationsHospital admissionHIV statusCaP diagnosisEtiologic diagnosis
2018
Herpes Zoster and Herpes Zoster Vaccine Rates Among Adults Living With and Without HIV in the Veterans Aging Cohort Study
Hawkins KL, Gordon KS, Levin MJ, Weinberg A, Battaglia C, Rodriguez-Barradas MC, Brown ST, Rimland D, Justice A, Tate J, Erlandson KM. Herpes Zoster and Herpes Zoster Vaccine Rates Among Adults Living With and Without HIV in the Veterans Aging Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 79: 527-533. PMID: 30179984, PMCID: PMC6203599, DOI: 10.1097/qai.0000000000001846.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyHerpes zoster ratesHerpes zosterAging Cohort StudyUninfected adultsUninfected veteransVaccine receiptZoster vaccineCohort studyHIV serostatusStudy periodCART-treated individualsCombination antiretroviral therapyHIV-1 RNAHigh rateLow CD4Vaccine guidelinesZoster vaccinationAntiretroviral therapyVaccine ratesStudy endPharmacy dataEffective vaccinePLWHZoster
2016
The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy
Edelman E, Gordon K, Tate J, Becker W, Bryant K, Crothers K, Gaither, Gibert C, Gordon A, Marshall B, Rodriguez‐Barradas M, Samet J, Skanderson M, Justice A, Fiellin D. The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy. HIV Medicine 2016, 17: 728-739. PMID: 27186715, PMCID: PMC5053822, DOI: 10.1111/hiv.12377.Peer-Reviewed Original ResearchConceptsCD4 cell countBaseline CD4 cell countCell countPrescribed opioidsImmunosuppressive propertiesVeterans Aging Cohort Study (VACS) dataCD4 cell count recoveryAntiretroviral therapy responseCell count recoveryShort-term opioidsViral load suppressionCohort study dataOverall disease severityYear of initiationPrimary independent variableOpioid durationAntiretroviral therapyCount recoveryComorbid conditionsPharmacy dataOpioid propertiesTherapy responseOpioidsPatientsHIV
2013
Sex Disparities in Overall Burden of Disease Among HIV-Infected Individuals in the Veterans Affairs Healthcare System
Blackstock OJ, Tate JP, Akgün KM, Crystal S, Duggal M, Edelman EJ, Gibert CL, Gordon KS, Rimland D, Rodriguez-Barradas MC, Wang EA, Fiellin DA, Justice AC. Sex Disparities in Overall Burden of Disease Among HIV-Infected Individuals in the Veterans Affairs Healthcare System. Journal Of General Internal Medicine 2013, 28: 577-582. PMID: 23807068, PMCID: PMC3695278, DOI: 10.1007/s11606-013-2346-z.Peer-Reviewed Original ResearchConceptsVeterans Affairs Healthcare SystemART initiationOverall burdenAntiretroviral therapyVeterans Aging Cohort Study Virtual CohortVACS Index scoreART-naïve HIVLower hemoglobin levelsHuman immunodeficiency virusBurden of diseaseHealthcare systemHIV biomarkersVACS IndexVACS-VCCause mortalityHIV careLiver dysfunctionART adherenceHemoglobin levelsImmunodeficiency virusHIV treatmentModifiable factorsPharmacy dataResultsComplete dataMultivariable regression
2009
Erectile Dysfunction Drug Receipt, Risky Sexual Behavior and Sexually Transmitted Diseases in HIV-infected and HIV-uninfected Men
Cook RL, McGinnis KA, Samet JH, Fiellin DA, Rodriquez-Barradas M, Kraemer KL, Gibert CL, Braithwaite RS, Goulet JL, Mattocks K, Crystal S, Gordon AJ, Oursler KK, Justice AC. Erectile Dysfunction Drug Receipt, Risky Sexual Behavior and Sexually Transmitted Diseases in HIV-infected and HIV-uninfected Men. Journal Of General Internal Medicine 2009, 25: 115-121. PMID: 19921112, PMCID: PMC2837496, DOI: 10.1007/s11606-009-1164-9.Peer-Reviewed Original ResearchConceptsErectile dysfunction drugsRisky sexual behaviorSexual behaviorUnprotected sexAdministrative pharmacy dataMinority of HIVUnknown HIV statusSample of HIVPercent of menElectronic medical recordsThousand seven hundredUninfected menHIV statusOutpatient clinicMore prescriptionsPharmacy dataMedical recordsCharacteristics of menPrevention interventionsCare providersDrug receiptHIVMultivariate analysisSubstance usersSeven hundredThe Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication
Freiberg MS, Leaf DA, Goulet JL, Goetz MB, Oursler KK, Gibert CL, Rodriguez-Barradas MC, Butt AA, Justice AC. The Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication. Journal Of General Internal Medicine 2009, 24: 334-340. PMID: 19127386, PMCID: PMC2642578, DOI: 10.1007/s11606-008-0891-7.Peer-Reviewed Original ResearchConceptsNCEP/ATP III criteriaATP III criteriaHIV viral loadViral loadAdult Treatment Panel guidelinesHigher HIV viral loadFive-site studyLipid lowering medicationsVeterans Aging CohortHIV infection statusLipid-Lowering TherapyProspective observational cohortCross-sectional analysisHIV-HCVLowering therapiesModifiable mediatorsObservational cohortResultsThe prevalenceHIV infectionHIV statusPharmacy dataCardiovascular diseasePanel guidelinesMAIN OUTCOMELow prevalence
2006
Development and Verification of a “Virtual” Cohort Using the National VA Health Information System
Fultz SL, Skanderson M, Mole LA, Gandhi N, Bryant K, Crystal S, Justice AC. Development and Verification of a “Virtual” Cohort Using the National VA Health Information System. Medical Care 2006, 44: s25-s30. PMID: 16849965, DOI: 10.1097/01.mlr.0000223670.00890.74.Peer-Reviewed Original ResearchConceptsPositive predictive valueIntegrated electronic medical recordsOutpatient codesPredictive valueCohort of veteransVA administrative dataElectronic medical recordsAdministrative dataMajority of subjectsInpatient codesSimilar HIVHAART eraHIV infectionCase RegistryPharmacy benefit managementPharmacy dataMedical recordsClinical dataLarge cohortConfirmatory laboratoryIndependent clinical dataHIVHealth information systemsVirtual cohortCohortRates and predictors of hepatitis C virus treatment in HCV–HIV‐coinfected subjects
BUTT AA, JUSTICE AC, SKANDERSON M, GOOD C, KWOH CK. Rates and predictors of hepatitis C virus treatment in HCV–HIV‐coinfected subjects. Alimentary Pharmacology & Therapeutics 2006, 24: 585-591. PMID: 16907891, DOI: 10.1111/j.1365-2036.2006.03020.x.Peer-Reviewed Original ResearchConceptsHepatitis C virus (HCV) treatmentC virus treatmentHepatitis C virusHepatitis C virus-infected subjectsHCV-HIVVirus-infected subjectsC virusVirus treatmentTreatment ratesVeterans Affairs National Patient Care DatabaseDrug useNational Patient Care DatabaseImpact of comorbiditiesEffect of comorbidityPatient Care DatabaseICD-9 codesCoinfected subjectsHispanic racePharmacy dataBlack raceCare databaseMajor depressionPsychiatric illnessMild depressionBipolar disorder
2005
How Does Depression Influence Diabetes Medication Adherence in Older Patients?
Kilbourne AM, Reynolds CF, Good CB, Sereika SM, Justice AC, Fine MJ. How Does Depression Influence Diabetes Medication Adherence in Older Patients? American Journal Of Geriatric Psychiatry 2005, 13: 202-210. PMID: 15728751, DOI: 10.1097/00019442-200503000-00005.Peer-Reviewed Original ResearchConceptsOverall medication adherenceMedication adherenceElectronic monitoring capsOlder patientsPharmacy dataBaseline surveyInadequate medication adherenceOral hypoglycemic medicationsPharmacy refill dataType 2 diabetesLower median percentagesPercentage of daysPercent of daysHypoglycemic medicationsAdequate medicationMedication useRefill dataPatients' baselineAdequate adherenceMedication coverageDepressed patientsDays' supplyPatient reportsPatientsMedian percentage