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YURS-Pregnancy Study Team

  • Professor, Obstetrics, Gynecology & Reproductive Sciences; Director, Division of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences

    Dr Vikki Abrahams is a Professor and Director of the Division of Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences.Dr Abrahams received her B.Sc. (hons) in Immunology in 1996, and was awarded a Ph.D. in Immunology in 2000, both from University College London. She continued her studies as a postdoctoral associate at Dartmouth Medical School and then at Yale University in the field of Reproductive Immunology. In 2004 she joined the faculty in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine. Since 2006 she has also been an Honorary Lecturer in the Maternal and Fetal Health Research Center at The University of Manchester, UK. Dr Abrahams' research focuses on understanding the role of innate immune Toll-like receptor and Nod-like receptor family members in placental and maternal-fetal immune responses, and their role in regulating pregnancy outcome, including those complicated by infections and by autoimmune diseases. Studies from the Abrahams laboratory has characterized the mechanisms by which Toll-like receptors, Nod-like receptors, and the inflammasome function in the placental trophoblast and fetal membranes in response to both infectious and non-infectious stimuli.Dr Abrahams is a member of the American Association of Immunologists, International Society for Immunology of Reproduction, Society for Reproductive Investigation, and the American Society of Reproductive Immunology. Dr Abrahams is the Associate Editor for Reviews of the American Journal of Reproductive Immunology and also serves on the editorial boards for a number of other journals within the Reproductive Sciences field.
  • Assistant Professor of Obstetrics and Gynecology; Wellness committee, Obstetrics, Gynecology & Reproductive Sciences

    Gary Altwerger, M.D. is a Gynecologic oncologist in the department of Obstetrics, Gynecology and Reproductive Sciences at Yale University School of Medicine. Dr. Altwerger has a special interest in early uterine cancer detection, identification of predictive and prognostic biomarkers in precancerous lesions, and has been published in novel treatment techniques for gynecologic cancers. He is the currently the Supervising Physician for the Inpatient Gynecologic Oncology Physicians Assistants, and Assistant Director of Inpatient Gynecologic Oncology Services, and serves on the IRB committee reviewing cancer research protocols at Yale New Haven Hospital. Dr. Altwerger’s laboratory is working on identifying ways to target DNA repair pathways in advanced uterine cancer. He additionally is implementing novel surgical techniques for the treatment of early-stage gynecologic cancer. Dr. Altwerger is the PI on multiple rare gynecologic cancer protocols.
  • Associate Research Scientist

    Murat Basar, PhD is an embryologist at Yale Fertility Center and Associate Research Scientist at the Yale University School of Medicine. He obtained his MSc and Ph.D. in Histology and Embryology from Istanbul University, Cerrahpasa, Turkey, with an integrated Ph.D. program at Yale University, USA. Dr. Basar has been involved in clinical embryology since 2009, working initially as an Embryologist at Yale Fertility Center before returning to practice embryology in Turkey. Fortunately, he chose to return to Yale Fertility Center and the Yale University School of Medicine in 2014. During his doctoral studies, Dr. Basar investigated cytokine-mediated regulation of inflammation in the endometrium and decidua during the menstrual cycle and pregnancy. He has published multiple original research articles and reviews in leading scientific journals in the field of implantation, pre-implantation embryo development, and pregnancy complications. He has also presented dozens of abstracts on implantation and pre-implantation embryo development topics at national and international medical conferences. Dr. Basar’s current research focuses on investigating the pathogenesis of endometriosis and endometriosis-related pain. He is on the Editorial Board of Molecular and Cellular Reproduction, Endocrinology and Disorders, International Journal of Scientific Advances.
  • Associate Professor of Obstetrics, Gynecology and Reproductive Sciences

    Dr. Flannery is an endocrinologist and Associate Professor with dual appointments in the Department of Obstetrics, Gynecology, and Reproductive Sciences (Reproductive Endocrinology) and the Department of Internal Medicine (Endocrinology). She received her undergraduate degree in Chemistry from Wellesley College in 1995 before obtaining her M.D. degree from Trinity College, Dublin in Ireland in 2001. She completed internship in medicine and surgery at St. James’s Hospital in Dublin Ireland, and then Internal Medicine residency in the Women’s Health Track at Jacobi Hospital, Albert Einstein College of Medicine in NY, where she also served as Chief Resident in Internal Medicine in 2005. She then went on to the Yale School of Medicine for her fellowship in Endocrinology & Metabolism. She pursued research fellowship at Yale, in the respective labs of Dr. Hugh Taylor, and of Dr. Gerald Shulman and Dr. Kitt Petersen, to combine interests in endometrial physiology and the pathophysiology of Type-2 diabetes mellitus. She was awarded an NIH K08 mentored career award then NIH R01 funding. Her translational research lab studies mechanisms for endometrial cancer development, and the effect of weight and diabetes on women's reproductive health. She sees patients with diabetes and endocrine disorders, with a specialty interest in diabetes prevention, weight management, Polycystic Ovary Syndrome, perimenopause, and gender-affirming hormone therapy.
  • Assistant Professor Adjunct

    Dr. Flores is Assistant Professor of Obstetrics, Gynecology and Reproductive Sciences at the Yale School of Medicine, and a Reproductive Scientist Development Program (RSDP) Scholar. Dr. Flores received her undergraduate training at the University of Southern California and received her medical degree from the Yale School of Medicine. She completed her residency in Obstetrics and Gynecology at Brown University/Women and Infants Hospital before returning to Yale to complete her fellowship in Reproductive Endocrinology and Infertility. During her fellowship, Dr. Flores was accepted into the RSDP scholars program, a National Institute of Health (NIH)- funded physician-scientist development program aimed at fostering the growth of young obstetrician-gynecologists committed to academic investigative careers in fundamental biomedical science. Her research is focused on determining the molecular mechanisms involved in the pathophysiology of endometriosis, in order to develop novel therapies aimed at treating this debilitating disease.  In addition to endometriosis, her clinical interests include infertility, and uterine disorders such as Asherman’s syndrome and uterine anomalies.Dr. Flores is the recipient of several research awards, including the Society of Reproductive Investigation (SRI)/Bayer Discovery Grant, the Bennack-Polan Foundation Grant, and the Prelude Fertility Travel Grant.  She has published peer-reviewed articles in leading scientific journals and is a reviewer for several journals.  Dr. Flores is equally committed to resident and medical student education, and serves as the faculty mentor for the Yale Medical Student Ob/Gyn Interest Group.
  • Senior Research Scientist in Obstetrics, Gynecology, and Reproductive Sciences; Director, Gyn/Endocrine Laboratory

    Dr. Seth Guller, trained as a biochemist, joined the Yale Fertility Center as Director of the Reproductive Endocrinology Laboratory in 2007. The function of this clinical laboratory is to provide rapid hormone analysis for patients as well as test results for research studies. Dr. Guller strives to implement new tests for the recently acquired Roche Cobas e411 analyzer to improve the quality of patient care. He has also directed a research laboratory for the last 21 years. Dr. Guller has published more than 75 peer-reviewed papers.
  • Assistant Professor of Obstetrics, Gynecology and Reproductive Sciences; Laboratory Director, Yale Fertility Center LGBTQI+ Program Contact; IVF Laboratory Director, Yale Medicine Greenwich Fertility

    After following an academic career including the degrees in BSc. in Biology (METU/ Ankara/Turkey) and MSc. And Ph.D. degrees in Biotechnology (2001) (METU/Ankara/Turkey), Cihan Halicigil joined to the Hacettepe University, Dept. of Obstetrics and Gynecology IVF unit in 2001.  He had his second MSc. From Leeds University in Clinical Embryology (2005). Since 2001, He has been involved over 13000 fresh cycles, and over 7000 frozen embryo transfer cycles. He has trained more than 40 clinical embryologists and IVF laboratory directors. He has directed Florence Nightingale Gayrettepe IVF laboratory and Acibadem Maslak IVF Laboratory back in Turkey during 2003-2015. Also, he has built or refurbished 17 IVF laboratories. He is an AAB certified high complexity laboratory director (HCLD) since 2017. After moving to USA in 2015, he helped to start and worked at the Carolinas Fertility Institute program in Winston-Salem, NC as the senior embryologist which became one of the most successful and distinguished programs in USA.  Dr. Halicigil's major interests are embryo culture, micromanipulation techniques, cryopreservation, PGT, timelapse microscopy, and laboratory automation.
  • Associate Professor of Obstetrics, Gynecology & Reproductive Sciences

    Gloria Huang, MD, is an internationally known expert in the treatment and prevention of ovarian, uterine and cervical cancers. Dr. Huang is skilled at minimally invasive surgery and is the principal investigator of a federally-funded cancer research laboratory. A board-certified gynecologic oncologist, Dr. Huang enjoys providing exceptional, individualized, comprehensive care to patients, bringing together multi-disciplinary clinical teams to achieve the best outcomes. She is passionate about advancing the field of gynecologic oncology through innovative scientific research and hopes her discoveries will lead to better treatments for patients. Watch a video with Dr. Gloria Huang >>
  • Professor, Obstetrics, Gynecology & Reproductive Sciences

    Dr. Yingqun Huang received her undergraduate and medical degrees from the Fudan University School of Medicine in 1988 and her Ph.D. in Biomedical Sciences from the University of Connecticut Health Center in 1997. She carried out her postdoctoral studies with Dr. Gordon Carmichael at the University of Connecticut Health Center (1997-1999) and then with Dr. Joan Steitz at Yale University School of Medicine (1999-2003) prior to becoming an Assistant Professor in 2003 in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine. She was promoted to Associate Professor in 2010 and then Full Professor in 2020. Her lab research centers on the mechanistic understanding of metabolic disorders including obesity, diabetes and infertility, in addition to reproductive tract tumors. Using cell and mouse models and an interdisciplinary approach her group generates new insights into disease pathogenesis with the ultimate goal of leveraging the knowledge to improve human health. She has made significant contributions in the field of noncoding RNAs and demonstrated the potential of long noncoding RNA H19 and microRNA let-7 as targets and/or therapeutics for uterine fibroids, ovarian and endometrial cancers, and type-2 diabetes. In the past 5 years, her research has extended to the epigenetic mechanisms of TET3 in metabolic diseases and cancer. Her current research projects include 1) TET3-mediated regulation of hepatic glucose production, NAFLD and liver fibrosis; 2) the role of TET3 in modulation of skeletal muscle insulin sensitivity; 3) the regulation of feeding, obesity, and other complex behaviors by TET3 through the hypothalamic AGRP neurons; and 4) development of therapeutic approaches (small molecule compounds and RNA therapeutics) to eating disorders, stress-related disorders, NAFLD, liver fibrosis, endometriosis, and ovarian cancer. Her contributions to science are highlighted by multiple publications in high impact journals, including Molecular Cell, Journal of Clinical Investigation, Nature Communications, EMBO Molecular Medicine, PNAS, Nucleic Acids Research, Cell Reports, Diabetes, and Oncogene. In addition to research, Dr. Huang is a dedicated teacher and mentor. She has mentored and trained many medical fellows, postdoctoral associates, and graduate students. Two of the medical fellows have become reproductive physician scientists holding Associate Professor positions. Dr. Huang has served as and will continue to be Director of Molecular Biology Core Training Laboratory for the Yale Women’s Reproductive Health Research program (WRHR). In recognition of her deep commitment to teaching and mentoring, she received the Harold Behrman Teaching Award in 2013.
  • Associate Professor Adjunct

    Dr. Amanda N. Kallen is Associate Professor of Obstetrics and Gynecology at the Yale School of Medicine and a member of the Reproductive Scientist Development Program (RSDP). She obtained her medical degree at the University of Connecticut and completed her Residency in Obstetrics and Gynecology at Yale-New Haven Hospital, followed by a fellowship in Reproductive Endocrinology and Infertility at the Yale School of Medicine. During her fellowship, she was accepted into the RSDP scholar program, an NIH-funded physician-scientist training program committed to training young obstetrician-gynecologists in biomedical science. Upon completion of her fellowship, she was recruited to join the Yale Division of Reproductive Endocrinology and Infertility.Dr. Kallen has published in leading scientific journals, and her current research program is focused on the investigation of the regulation of gene expression in granulosa cells. Her clinical interests include pediatric and adolescent gynecology and endocrinology, infertility, and premature ovarian insufficiency. She is the recipient of multiple awards for teaching, clinical excellence, and research, including the Yale University "Resident of Excellence" award, the North American Menopause Society / Teva Medical Resident Excellence Award, the American Society of Reproductive Medicine (ASRM) Resident Reporter award, the Association of Professors of Gynecology and Obstetrics Resident Scholar award.Dr. Kallen is highly active with the American Congress of Obstetricians and Gynecologists (ACOG), currently serving on the Executive Board as the national Junior Fellow Congress Advisory Council Chair. She is also a graduate of ACOG's Robert Cefalo Leadership Institute. Additionally, she plays an active role in medical student and resident education and serves as a faculty mentor for the Yale medical student Ob/Gyn Interest Group. Lastly, she serves as an Interactive Associate for Fertility & Sterility and a reviewer for multiple journals, and is a member of the ASRM Women's Council.
  • Research Scientist in Obstetrics, Gynecology, and Reproductive Sciences; Director, Reproductive and Placental Research Unit

    Harvey J. Kliman has, in addition to an M.D., a Ph.D. in cellular biochemistry from the University of Chicago. He is currently a Research Scientist in the Department of Obstetrics and Gynecology, Yale University School of Medicine and the Director of the Reproductive and Placental Research Unit with a special interest in infertility and pregnancy complications. He has over thirty years of anatomic pathology training with particular emphasis in electron microscopy, immunohistochemistry, endometrial and placental pathology. He has over ten patents, including the patent for the Endometrial Function Test® (EFT®)—“The soil test for the endometrium®” and “Method and system for determining placental volume.” His contributions in the field of placental research include the development of the “Kliman” method of trophoblast purification, research into the mechanisms of trophoblast differentiation and invasion, the role and genesis of syncytial knots, the discovery of placental fetal fibronectin, and more recently, the clinical utility of abnormalities in placental villous growth patterns, especially trophoblast invaginations and inclusions, to diagnose genetic abnormalities in pregnancy, including autism.
  • Associate Professor of Clinical Obstetrics, Gynecology & Reproductive Sciences; Director, Advanced Endoscopic Reproductive Surgery Program; Director, Reproductive Endocrinology and Infertility Elective

    Dr. Kodaman is Assistant Professor of Obstetrics and Gynecology at the Yale School of Medicine and serves as the Director of the Advanced Endoscopic Reproductive Surgery Program specializing in surgery for fibroids, endometriosis, and other female reproductive disorders. In addition to advanced endoscopic reproductive surgery, Dr. Kodaman’s interests include infertility, abnormal uterine bleeding, primary ovarian insufficiency, PCOS, and Asherman’s syndrome. Dr. Kodaman also serves as one of the physicians in the PCOS Program at Yale where her focus is the cardiovascular risks associated with this endocrine disorder.Dr Kodaman received her medical training at the Yale School of Medicine and her graduate degree in pharmacology from Yale University. She subsequently completed her internship and residency at Yale-New Haven Hospital and a fellowship in Reproductive Endocrinology and Infertility, also at Yale.Dr. Kodaman is board certified in both Obstetrics and Gynecology and Reproductive Endocrinology and Infertility. She has over 30 publications and multiple research interests, including the regulation of angiogenesis and the effects of oxidative stress on reproductive function. She serves as a reviewer for various scientific journals, has lectured at numerous meetings, and plays an active role in educating undergraduates, medical students, and residents at Yale.
  • Research Scientist in Obstetrics, Gynecology, and Reproductive Sciences

    My current interests involved endometrial angiogenesis and hemostasis in both the non-pregnant and pregnant states. To this end we have recently found that the molecule "ICON" developed by Hu and Garen has been successful in eradicating endometriotic lesions in a mouse model of endometriosis. This occurs by destroying the aberrant vasculature supporting the disease. Lately I have become interested in reproductive immunology and am part of a program project directed by Dr. Gil Mor in which I study the maternal part of the innate immune system during implantation. Lastly, together with Dr. Hugh Taylor, I have learned and published several papers involving the endometrial stem cell population and the possible contributions of immune cells on the stem cell niche.