2001
A triple color FISH technique for mouse chromosome identification
Henegariu O, Dunai J, Chen X, Korenberg J, Ward D, Greally J. A triple color FISH technique for mouse chromosome identification. Mammalian Genome 2001, 12: 462-465. PMID: 11353394, DOI: 10.1007/s003350020038.Peer-Reviewed Original ResearchImprovements in cytogenetic slide preparation: Controlled chromosome spreading, chemical aging and gradual denaturing
Henegariu O, Heerema N, Wright L, Bray‐Ward P, Ward D, Vance G. Improvements in cytogenetic slide preparation: Controlled chromosome spreading, chemical aging and gradual denaturing. Cytometry 2001, 43: 101-109. PMID: 11169574, DOI: 10.1002/1097-0320(20010201)43:2<101::aid-cyto1024>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsComparative genomic hybridizationClassical banding techniquesSitu hybridization applicationsChromosomal integrityChromosome spreadsMultiplex FISHMolecular cytogeneticsFISH applicationsChromosome spreadingFISH techniqueGenomic hybridizationEnvironmental conditionsSitu hybridizationBanding techniquesChromosomesHybridizationReproducible protocolFISH resultsCytogenetic slidesCell suspensionsSlide preparationFishMetaphase
1999
p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells.
Mantel C, Braun S, Reid S, Henegariu O, Liu L, Hangoc G, Broxmeyer H. p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells. Blood 1999, 93: 1390-8. PMID: 9949183, DOI: 10.1182/blood.v93.4.1390.404k25_1390_1398.Peer-Reviewed Original Research
1998
Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion*
Yu D, Qu C, Henegariu O, Lu X, Feng G. Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion*. Journal Of Biological Chemistry 1998, 273: 21125-21131. PMID: 9694867, DOI: 10.1074/jbc.273.33.21125.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell AdhesionCell Adhesion MoleculesCell LineCell MovementCytoskeletal ProteinsFibroblastsFocal Adhesion Kinase 1Focal Adhesion Protein-Tyrosine KinasesHeterozygoteHomozygoteIntracellular Signaling Peptides and ProteinsMicePaxillinPhenotypePhosphoproteinsProtein Tyrosine Phosphatase, Non-Receptor Type 11Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesProtein-Tyrosine KinasesSH2 Domain-Containing Protein Tyrosine PhosphatasesConceptsShp-2 mutant cellsMutant cellsFocal adhesionsSHP-2Tyrosine phosphataseProtein tyrosine phosphatase SHP-2SHP-2 tyrosine phosphataseCell spreadingFunctional SHP-2SHP-2 mutationsPhosphatase SHP-2Cytoplasmic tyrosine phosphataseF-actin aggregationWild-type cellsFocal adhesion kinaseMesodermal patterningSH2 domainFAK dephosphorylationCytoskeletal architectureSrc SH2Adhesion kinaseSignal relayCell peripheryGrowth factor receptorCell motilityMolecular cytogenetic analysis of patients with holoprosencephaly and structural rearrangements of 7q
Vance G, Nickerson C, Sarnat L, Zhang A, Henegariu O, Morichon‐Delvallez N, Butler M, Palmer C. Molecular cytogenetic analysis of patients with holoprosencephaly and structural rearrangements of 7q. American Journal Of Medical Genetics 1998, 76: 51-57. PMID: 9508065, PMCID: PMC6775641, DOI: 10.1002/(sici)1096-8628(19980226)76:1<51::aid-ajmg9>3.0.co;2-s.Peer-Reviewed Original ResearchMeSH KeywordsCell LineChromosome AberrationsChromosome DeletionChromosomes, Human, Pair 13Chromosomes, Human, Pair 22Chromosomes, Human, Pair 7CytogeneticsFemaleGenetic MarkersHedgehog ProteinsHoloprosencephalyHumansIn Situ Hybridization, FluorescenceInfantInfant, NewbornKaryotypingMaleMosaicismPolymerase Chain ReactionProteinsTrans-ActivatorsTranslocation, GeneticConceptsSonic hedgehog geneHedgehog geneCell linesDifferent chromosome regionsStructural rearrangementsHuman Sonic Hedgehog genePatient cell linesMolecular cytogenetic analysisChromosome regionsChromosome 7Embryonic forebrainLong armGenesSitu hybridizationPolymerase chain reaction amplificationHPE3Chain reaction amplificationCytogenetic analysisMidline cleavageReaction amplificationRearrangementPhenotypeCritical regionLinesHybridization