2023
Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model
Sung E, Park M, Song S, Alanya H, Henegariu O, Liu J, Erson-Omay E, Sime P, Chae W. Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model. Frontiers In Immunology 2023, 14: 1247330. PMID: 38162655, PMCID: PMC10757334, DOI: 10.3389/fimmu.2023.1247330.Peer-Reviewed Original ResearchConceptsLung injury modelMacrophage polarizationTissue repair processInjury modelMonocyte-derived alveolar macrophagesInjury-induced inflammationTissue repairRepair processRole of WntGene expression profilesImmunomodulatory roleIL-13Tissue injuryImmune responseInflammationCollagen depositionAlveolar macrophagesMacrophagesTissue homeostasisProtein expressionGene expressionRegulatory ligandsExpression profilesWnt antagonist Dickkopf1Dickkopf1
2017
HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE?
Canaan A, Arjona C, Gulez B, Seay M, Zhang J, Henegariu O, Garcia Milian R. HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE? Innovation In Aging 2017, 1: 978-978. PMCID: PMC6185008, DOI: 10.1093/geroni/igx004.3533.Peer-Reviewed Original ResearchDifferential gene expressionRNA sequence analysisStem cell populationNovel mechanistic insightsAdipogenic transcription factorsAdipocyte metabolic functionMammalian agingHematopoietic stem cellsTranscription factorsGene expressionPathway analysisPleiotropic natureKnockout miceFAT10 geneMaximal lifespanDruggable targetsMetabolic functionsStem cellsTRANSFAC analysisFAT10Mediator genesMechanistic insightsMost tissuesCell populationsGenes
1995
The human A1 adenosine receptor: ligand binding properties, sites of somatic expression and chromosomal localization
Rivkees S, Lasbury M, Stiles G, Henegariu O, Curtis C, Vance G. The human A1 adenosine receptor: ligand binding properties, sites of somatic expression and chromosomal localization. Endocrine 1995, 3: 623-629. PMID: 21153220, DOI: 10.1007/bf02746338.Peer-Reviewed Original ResearchA1AR geneHuman-rodent somatic cell hybridsChromosome 1Human A1ARHuman chromosome 1Somatic cell hybridsLigand binding propertiesChromosomal localizationChromosomal locationMammalian biologyCell hybridsGene expressionNorthern analysisGenesCHO cellsImportant biological effectsLong armPCR analysisSouthern blottingSitu hybridizationHuman A1 adenosine receptorSomatic expressionHigh-affinity receptorHuman physiologyHuman tissues