Receptor for advanced glycation end products is required for normal T cell activation and development of T cell induced lung inflammation (36.10)
Akirav E, Henegariu O, Clynes R, Schmidt A, Herold K. Receptor for advanced glycation end products is required for normal T cell activation and development of T cell induced lung inflammation (36.10). The Journal Of Immunology 2009, 182: 36.10-36.10. DOI: 10.4049/jimmunol.182.supp.36.10.Peer-Reviewed Original ResearchRAGE-/- miceT cell activationIntranasal OVA challengeT cellsOT-IICell activationNormal T cell activationOVA challengeRobust T cell infiltrationReduced T cell activationTranscription factor T-betAdvanced glycation end productsMediastinal lymph nodesT cell infiltrationOT-II miceGlycation end productsAdvanced glycation endproductsGATA-3 expressionIL5 productionCD62L expressionLung inflammationIFNγ expressionLymph nodesCellular infiltrateWT mice