Skip to Main Content

Kevin Sheth, MD

Professor of Neurology and Neurosurgery; Executive Director of the NNCTU and Vice Chair for Clinical and Translational Research in the Departments of Neurology and Neurosurgery. Director, Yale Center for Brain & Mind Health.

Contact Information

Kevin Sheth, MD

Patient Care Locations



Dr. Kevin Sheth is a founding Director of the Yale Center for Brain & Mind Health and the Vice Chair for Clinical and Translational Research for the departments of Neurology. and Neurosurgery. He leads prevention efforts in neurologically vulnerable populations and works towards advancing therapies for acute brain injury such as stroke and brain hemorrhage. In pioneering the development of new strategies to treat brain swelling, his work has changed the fundamental approach to brain injury in the ICU and spurred the creation of new technologies in drug delivery and neuroimaging. Highly collaborative, interdisciplinary efforts from the lab have culminated in the first phase III trial to prevent brain swelling in stroke, the first phase III NIH funded prevention trial in brain hemorrhage, and the deployment of the first portable bedside MRI for brain injury in the world. His team at Yale has served as a national model for academic critical care neurology units. In recent years his group has also turned their attention to public health prevention efforts, focusing on cardiometabolic risk factors that can prevent decline in brain health resulting from stroke, dementia, and depression.

He is currently a principal investigator for two NIH neuroscience networks, StrokeNet, and SIREN. He is a multi-PI for four additional RO1/UO1 awards from the NIH. Dr. Sheth has served as PI or co-PI for 8 multicenter clinical trials in stroke. He is a winner of the prestigious Robert Siekert Award from the American Heart Association (AHA), the Derek Denny Brown Award from the American Neurological Association and an elected member of the American Society for Clinical Investigation (ASCI). Most recently, he was the recipient of the Stroke Research Mentorship Award from the American Heart Association. Dr. Sheth is the author of over 300 publications. His work has been showcased in The Washington Post, Wall Street Journal, Scientific American, NPR, and CNN.

Finally, Dr. Sheth has formed exciting partnerships with entrepreneurs, pharmaceutical companies, and medical device start-ups to bring forward highly innovative solutions. These efforts have resulted in extensive knowledge of FDA pathways, development of phase I-III drug programs, and implementation of new technology into the clinical workspace. The principal theme of his efforts are towards collaboration and an improved understanding of neurological disease.

Education & Training

  • Fellow, Vascular Neurology & Neurocritical Care
    Massachusetts General Hospital/Brigham & Women's Hospital (2009)
  • Chief Resident
    Massachusetts General Hospital/Brigham & Women's Hospital (2007)
  • Resident
    Massachusetts General Hospital/Brigham & Women's Hospital (2006)
  • Intern
    Brigham and Women's Hospital (2004)
  • MD
    University of Pennsylvania Medical School (2003)
  • BA
    Johns Hopkins University (1999)

Honors & Recognition

AwardAwarding OrganizationDate
Team Science AwardAssociation for Clinical and Translational Science (ACTS)2022
Outstanding Investigator AwardAmerican Federation for Medical Research2022
Stroke Mentorship AwardAmerican Heart Association2021
Team Science AwardAssociation for Clinical and Translational Science2020
Elected MemberAmerican Society of Clinical Investigation (ASCI)2020
Derek Denny-Brown Young Neurological Scholar AwardAmerican Neurological Association2017
Stroke Care in Emergency Medicine AwardAmerican Heart Association/American Stroke Association2017
Family Centered Care Innovation AwardSociety for Critical Care Medicine2017
Robert G. Siekert Stroke Investigator AwardAmerican Heart Association/American Stroke Association2013
Visiting Professor Award, Mannheim GermanyGerman Society of Neurocritical Care and Emergency Medicine (ANIM) Conference2012
Clinician Scientist AwardPassano Foundation2012
Alpha Omega AlphaUniversity of Pennsylvania School of Medicine2002
Phi Beta KappaJohns Hopkins University1999

Professional Service

American Neurological AssociationBoard of Directors2021 - Present
American Society for Clinical InvestigationMember2020 - Present
Neurocritical Care SocietyBoard of Directors2014 - Present
NINDSNSD-K Clinical Trials Study Section2012 - Present
National Aeronautics Space Administration (NASA)Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions – “Visual Impairment and Intracranial Pressure in Astronauts”2012 - Present
American Heart AssociationProfessional Education Committee2011 - Present
Neurocritical Care SocietyNeurocritical Care Research Network Executive Committee2011 - Present

Departments & Organizations