2021
Fenestrated pedicle screws for thoracolumbar instrumentation in patients with poor bone quality: Case series and systematic review of the literature
Ehresman J, Pennington Z, Elsamadicy AA, Hersh A, Lubelski D, Lehner K, Cottrill E, Schilling A, Lakomkin N, Ahmed AK, Lo SF, Sciubba DM. Fenestrated pedicle screws for thoracolumbar instrumentation in patients with poor bone quality: Case series and systematic review of the literature. Clinical Neurology And Neurosurgery 2021, 206: 106675. PMID: 34020324, DOI: 10.1016/j.clineuro.2021.106675.Peer-Reviewed Original ResearchConceptsPulmonary cement embolismFenestrated pedicle screwsCement leakageBone qualityCement embolismInstrumented fusionHardware looseningOsteoporotic fracturesPedicle screwsSystematic reviewSymptomatic pulmonary cement embolismNon-augmented patientsSingle-surgeon seriesDegenerative spine diseaseHigh-quality evidencePoor bone qualityEndpoints of interestLow reported ratesPathologic fractureCase seriesSpine metastasesFenestrated screwsSpine diseasePRISMA guidelinesPatients
2020
In Reply: Assessing Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium.
Elsamadicy AA. In Reply: Assessing Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium. Spine 2020, 45: e605. PMID: 32205698, DOI: 10.1097/brs.0000000000003489.Peer-Reviewed Original ResearchIndependent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction.
Elsamadicy AA, Adil SM, Charalambous L, Drysdale N, Koo AB, Lee M, Kundishora AJ, Camara-Quintana J, Kolb L, Laurans M, Abbed K, Karikari IO. Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction. Spine 2020, 45: 268-274. PMID: 31996654, DOI: 10.1097/brs.0000000000003260.Peer-Reviewed Original ResearchConceptsIntraoperative blood transfusionComplex spinal fusionAllogenic blood transfusionPostoperative deliriumBlood transfusionSpinal fusionIndependent associationDeformity correctionMultivariate nominal-logistic regression analysisPrimary complex spinal fusionAdult spine deformity patientsAdult deformity correctionBetter overall patient careGreater complication risksRetrospective cohort studySpine deformity patientsOverall patient careNominal logistic regression analysisMajor academic institutionHospital stayCohort studyBlood lossPrimary outcomeComplication riskDeformity patients
2019
Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study
Elsamadicy AA, Charalambous L, Adil SM, Drysdale N, Lee M, Koo AB, Chouairi F, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study. World Neurosurgery 2019, 129: e311-e316. PMID: 31132486, DOI: 10.1016/j.wneu.2019.05.135.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionNarcotic refillsPain scoresSpinal fusionAffective disordersDeformity correctionNarcotic useDeformity patientsAD cohortPatient-reported pain scoresAdult spine deformity patientsAdult deformity correctionPostoperative pain scoresPostoperative complication ratePreoperative narcotic useHigher pain scoresSpinal deformity patientsSpine deformity patientsMajor academic institutionAmbulatory statusComplication ratePatient demographicsPrimary outcomePostoperative perceptionAssociation Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction
Elsamadicy AA, Drysdale N, Adil SM, Charalambous L, Lee M, Koo A, Freedman IG, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Association Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 128: e231-e237. PMID: 31009775, DOI: 10.1016/j.wneu.2019.04.107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone TransplantationDepressionFemaleHumansIntraoperative Neurophysiological MonitoringLaminectomyLength of StayMaleMiddle AgedMobility LimitationNarcoticsOsteotomyPainPain MeasurementPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPreoperative PeriodSpinal DiseasesSpinal FusionConceptsComplex spinal fusionPain scoresPerioperative complication ratePreoperative narcotic useComplication rateSpinal fusionAmbulatory statusNarcotic usePatient demographicsDeformity correctionPatient-reported pain scoresPrimary complex spinal fusionAdult deformity correctionLast pain scoreNon-user cohortsPostoperative pain scoresPostoperative complication rateHigher pain scoresPhysical therapy regimensPrevalence of depressionGreater mean ageUse of narcoticsMajor academic institutionAmbulatory dayPreoperative useReduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction
Elsamadicy AA, Camara-Quintana J, Kundishora AJ, Lee M, Freedman IG, Long A, Qureshi T, Laurans M, Tomak P, Karikari IO. Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 127: e108-e113. PMID: 30876992, DOI: 10.1016/j.wneu.2019.02.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexComorbidityDiabetes MellitusDyslipidemiasElective Surgical ProceduresFemaleHeart DiseasesHumansHypertensionLaminectomyLength of StayMaleMiddle AgedObesityPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesSpinal DiseasesSpinal FusionTreatment OutcomeUnited StatesYoung AdultConceptsPatient-reported pain scoresComplex spinal fusionPain scoresImpact of obesityReadmission ratesSurgical outcomesDeformity correctionSpinal fusionAmbulatory statusPatient demographicsComplication ratePreoperative body mass indexPrimary complex spinal fusionShort-term surgical outcomesAdult deformity correctionInferior surgical outcomesPostoperative complication profileLength of surgeryPostoperative complication ratePrevalence of obesityBody mass indexPatient-reported outcomesComplex spinal surgeryPaucity of dataMajor academic institutionRate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2018
Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complication Rates, Ambulation, and Length of Hospital Stay After Elective Spinal Fusion (≥3 Levels) in Elderly Spine Deformity Patients
Elsamadicy AA, Sergesketter AR, Kemeny H, Adogwa O, Tarnasky A, Charalambous L, Lubkin DET, Davison MA, Cheng J, Bagley CA, Karikari IO. Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complication Rates, Ambulation, and Length of Hospital Stay After Elective Spinal Fusion (≥3 Levels) in Elderly Spine Deformity Patients. World Neurosurgery 2018, 116: e1122-e1128. PMID: 29870850, DOI: 10.1016/j.wneu.2018.05.185.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseElective spinal fusionPostoperative complication rateObstructive pulmonary diseaseSpine deformity patientsHospital stayCOPD cohortComplication rateSpinal fusionDeformity patientsPulmonary diseaseIncidence of durotomyModifiable risk factorsProportion of smokersLength of staySpinal deformity patientsHealth care resourcesHigh rateMajor academic institutionPostoperative feverPostoperative pneumoniaAmbulatory statusHospital lengthPostoperative complicationsElderly patientsPreoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity
Elsamadicy AA, Adogwa O, Ongele M, Sergesketter AR, Tarnasky A, Lubkin DET, Drysdale N, Cheng J, Bagley CA, Karikari IO. Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity. World Neurosurgery 2018, 112: e348-e354. PMID: 29355811, DOI: 10.1016/j.wneu.2018.01.046.Peer-Reviewed Original ResearchConceptsElderly male patientsPreoperative Hgb levelsElective spinal fusionHealth care useHgb levelsSpinal fusionMale patientsPostoperative deliriumHemoglobin levelsCare useMean Hgb levelsNon-wound infectionsPreoperative hemoglobin levelLower hemoglobin levelsLower Hgb levelsQuality of careMajor academic institutionPreoperative HgbHospital stayPreoperative levelsPrimary outcomePreoperative identificationHematoma formationMedical recordsSpine surgery
2017
30-Day Readmission After Spine Surgery
Adogwa O, Elsamadicy AA, Han JL, Karikari IO, Cheng J, Bagley CA. 30-Day Readmission After Spine Surgery. Spine 2017, 42: 520-524. PMID: 28350632, DOI: 10.1097/brs.0000000000001779.Peer-Reviewed Original ResearchConceptsElective spine surgeryUnplanned readmissionSpine surgeryEarly readmissionHospital stayUnplanned early readmissionsCauses of readmissionDays of dischargeRetrospective cohort reviewMajority of patientsCommon primary reasonsPost-discharge careDuke University HospitalSkilled nursing facilitiesQuality of careNonsurgical complicationsRefractory painCohort reviewDischarge careLumbar decompressionSD ageEmergency departmentUniversity HospitalRisk factorsCommon causeRisk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients
Elsamadicy AA, Adogwa O, Reddy GB, Sergesketter A, Warwick H, Jones T, Cheng J, Bagley CA, Karikari IO. Risk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients. World Neurosurgery 2017, 101: 270-274. PMID: 28192260, DOI: 10.1016/j.wneu.2017.02.001.Peer-Reviewed Original ResearchConceptsElective spine surgeryPostoperative complication rateIndependent predictorsSpine surgeryComplication rateSpine deformityRisk factorsAMS cohortPatient demographicsMental statusInferior surgical outcomesAltered mental statusMultivariate stepwise regression analysisIntensive care unitMajor academic institutionICU transferAdult patientsIntraoperative variablesPulmonary embolismPrimary outcomeCare unitSurgical outcomesMedical recordsReadmissionPatientsImpact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity
Elsamadicy AA, Adogwa O, Lydon E, Reddy G, Kaakati R, Sergesketter A, Gottfried ON, Karikari IO. Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity. World Neurosurgery 2017, 101: 283-288. PMID: 28192259, DOI: 10.1016/j.wneu.2017.02.002.Peer-Reviewed Original ResearchConceptsComplex spinal fusionIntraoperative monitoringPostoperative complicationsReadmission ratesSpinal fusionAdult patientsSpinal deformityUse of IOMIntensive care unit transferSimilar postoperative complicationsBody mass indexOverall surgical outcomeSpinal cord injuryMajor academic institutionIOM useHospital stayComplication rateNerve injuryPatient demographicsTranscranial motorPrimary outcomeMass indexOperative timeSensorimotor deficitsSmoking status
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgeryImpact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients
Elsamadicy AA, Wang TY, Back AG, Sergesketter A, Warwick H, Karikari IO, Gottfried ON. Impact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients. World Neurosurgery 2016, 96: 429-433. PMID: 27667578, DOI: 10.1016/j.wneu.2016.09.057.Peer-Reviewed Original ResearchConceptsIntraoperative steroidsHospital staySpine surgeryInfection ratePostoperative complicationsPatient demographicsUse cohortSteroid useLong-term steroid useSuperficial surgical site infectionDuke University Medical CenterIntraoperative steroid useSpine surgery patientsPostoperative complication ratePostoperative infection rateShorter hospital staySurgical site infectionUrinary tract infectionUniversity Medical CenterLength of operationLower ratesLow infection rateAdult patientsComplication rateSurgery patientsPatient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery
Elsamadicy AA, Adogwa O, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery. World Neurosurgery 2016, 96: 148-151. PMID: 27593714, DOI: 10.1016/j.wneu.2016.08.097.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexCase-Control StudiesComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisObesityPatient ReadmissionPneumoniaPostoperative ComplicationsRadiculopathyRisk FactorsSpinal DiseasesSpinal FusionSpinal StenosisSpondylolisthesisSurgical Wound InfectionUrinary Tract InfectionsConceptsElective spine surgeryBody mass indexPreoperative body mass indexMultivariate logistic regression analysisDays of dischargeIndependent risk factorHospital readmissionSpine surgeryLogistic regression analysisPreoperative obesityReadmission ratesIndependent predictorsMass indexRisk factorsEarly unplanned hospital readmissionPatient body mass indexUnplanned hospital readmissionPostoperative complication rateAppropriate risk stratificationPrevalence of obesityMajor academic medical centerAcademic medical centerRegression analysisHealth care climateIndex surgeryPreoperative Nutritional Status is an Independent Predictor of 30-day Hospital Readmission After Elective Spine Surgery
Adogwa O, Elsamadicy AA, Mehta AI, Cheng J, Bagley CA, Karikari IO. Preoperative Nutritional Status is an Independent Predictor of 30-day Hospital Readmission After Elective Spine Surgery. Spine 2016, 41: 1400-1404. PMID: 26953667, DOI: 10.1097/brs.0000000000001551.Peer-Reviewed Original ResearchConceptsElective spine surgeryPreoperative serum albumin levelDays of dischargeIndependent risk factorSerum albumin levelHospital readmissionSpine surgeryRisk factorsReadmission ratesPreoperative malnutritionMalnourished patientsAlbumin levelsIndependent predictorsThirty-day hospital readmission ratesNutritional statusMultivariate logistic regression analysisPre-operative malnutritionPreoperative nutritional statusUnplanned hospital readmissionModifiable risk factorsPostoperative complication rateRetrospective cohort reviewHospital readmission ratesIdentification of patientsMajor academic medical center