2024
Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditionsAssessing a revised-risk analysis index for morbidity and mortality after spine surgery for metastatic spinal tumors
Elsamadicy A, Serrato P, Sadeghzadeh S, Sayeed S, Hengartner A, Khalid S, Lo S, Shin J, Mendel E, Sciubba D. Assessing a revised-risk analysis index for morbidity and mortality after spine surgery for metastatic spinal tumors. Journal Of Neuro-Oncology 2024, 1-16. PMID: 39320656, DOI: 10.1007/s11060-024-04830-z.Peer-Reviewed Original ResearchModified frailty index-5Length of stayRAI-revMetastatic spinal tumorsPredicting 30-day mortalityReceiver operating characteristicArea under the curveSpine surgeryFrail patientsSpinal tumorsNo significant differenceSpinal pathologyMultivariate analysisMethodsA retrospective cohort studySignificant differenceExtended length of stayReceiver operating characteristic analysisACS NSQIP databasePredictors of extended length of stayRetrospective cohort studyMultidisciplinary decision makingMetastatic diseaseNSQIP databasePatient ageSpinal surgeryImpact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis
Aghajanian S, Shafiee A, Athar M, Mohammadifard F, Goodarzi S, Esmailpur F, Elsamadicy A. Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis. Journal Of Clinical Medicine 2024, 13: 3247. PMID: 38892958, PMCID: PMC11172961, DOI: 10.3390/jcm13113247.Peer-Reviewed Original ResearchNon-routine dischargeSpine surgerySurgical complicationsSurgical outcomesStatistically significant higher rateUrinary tract infectionSurgical site infectionDeep vein thrombosisLength of hospitalizationSystematic reviewNon-depressed controlsSignificantly higher ratesUrinary retentionPostoperative medicationTract infectionsPostoperative outcomesPulmonary embolismSite infectionSpinal surgeryVein thrombosisImpact of depressionPooled analysisDepressed patientsHematoma formationHospital length
2020
Geographic Variation in Outcomes and Costs After Spinal Fusion for Adolescent Idiopathic Scoliosis
Koo AB, Elsamadicy AA, Kundishora AJ, David WB, Lee M, Hong CS, Lee V, Kahle KT, DiLuna M. Geographic Variation in Outcomes and Costs After Spinal Fusion for Adolescent Idiopathic Scoliosis. World Neurosurgery 2020, 136: e347-e354. PMID: 31917315, DOI: 10.1016/j.wneu.2019.12.175.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisLength of surgeryAdolescent patientsSpinal fusionIdiopathic scoliosisMultilevel posterior spinal fusionHealth care resource utilizationGreater complication ratePosterior spinal fusionPosterior spinal surgeryPostoperative complicationsComplication ratePrimary outcomeAIS patientsSpinal surgeryPatientsSurgeryAdmissionRegional variationComplicationsFurther studiesOutcomesCohortScoliosisTotal cost
2018
Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients.
Elsamadicy AA, Ren X, Kemeny H, Charalambous L, Sergesketter AR, Rahimpour S, Williamson T, Goodwin CR, Abd-El-Barr MM, Gottfried ON, Xie J, Lad SP. Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients. Neurosurgery 2018, 84: 758-767. PMID: 29893899, DOI: 10.1093/neuros/nyy215.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryChronic obstructive pulmonary disorderLumbar spine surgeryNational Readmission DatabaseUnplanned hospital readmissionPatient risk factorsUnplanned readmissionHospital readmissionSpine surgeryDeficiency anemiaInsurance statusRisk factorsElective spinal surgeryUnplanned readmission rateObstructive pulmonary disorderMultivariate regression analysisPaucity of dataInpatient complicationsNational healthcare expendituresReadmission ratesDural tearPulmonary disordersIndependent associationPatient outcomesSpinal surgery
2017
Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity
Adogwa O, Elsamadicy AA, Sergesketter A, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity. World Neurosurgery 2017, 110: e67-e72. PMID: 29081391, DOI: 10.1016/j.wneu.2017.10.081.Peer-Reviewed Original ResearchConceptsNormal cognitive statusCognitive impairmentCognitive statusOlder patientsSLUMS scorePreoperative cognitive impairmentElective spinal surgeryPreoperative cognitive statusStandard deviation ageAdult degenerative scoliosisBaseline cognitive impairmentSevere cognitive impairmentMental status testsMild cognitive impairmentPostoperative lengthPreoperative scoresDeviation ageGeriatric patientsDegenerative scoliosisIndependent associationSpinal surgeryDeformity correctionPatientsSurgeryCognitive screeningRelationship Among Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis
Adogwa O, Elsamadicy AA, Sergesketter AR, Black C, Tarnasky A, Ongele MO, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. Relationship Among Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis. World Neurosurgery 2017, 107: 471-476. PMID: 28826716, DOI: 10.1016/j.wneu.2017.07.165.Peer-Reviewed Original ResearchConceptsElective spinal surgeryAmbulation abilityElderly patientsHospital dischargeComplication rateHospital stayPostoperative outcomesVAS scoresSpinal surgeryDepression ScaleVisual analog scale scoreSignificant differencesElective spine surgeryInferior postoperative outcomesPreoperative gait speedAnalog scale scoreDepressed elderly patientsPatient-reported outcomesAdult degenerative scoliosisPerception of painBoard-certified geriatriciansPostoperative complicationsBaseline demographicsIntraoperative variablesPrimary outcomeImpact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients
Nayar G, Elsamadicy AA, Zakare-Fagbamila R, Farquhar J, Gottfried ON. Impact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients. World Neurosurgery 2017, 100: 69-73. PMID: 28057592, DOI: 10.1016/j.wneu.2016.12.098.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedMood DisordersMultivariate AnalysisPatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsProspective StudiesRecovery of FunctionRegression AnalysisRetrospective StudiesRisk FactorsSelf ReportSpineConceptsDecompressive spinal surgeryIndependent risk factorSpinal surgeryAffective disordersRisk factorsOutcome measuresBaseline functionPatient-reported outcome measuresPoor baseline qualitySpinal surgery patientsWorse postoperative outcomesSingle-institution studyMain outcome measuresSelf-reported recoveryRegression analysisMultivariate regression analysisMajor academic institutionBaseline demographicsPerioperative variablesPostoperative outcomesSurgery patientsMore smokersSurgical outcomesPostoperative expectationsControl cohort
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgery