2020
Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex
Wang BS, Bernardez Sarria MS, An X, He M, Alam NM, Prusky GT, Crair MC, Huang ZJ. Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex. Neuron 2020, 109: 502-515.e7. PMID: 33290732, PMCID: PMC7943176, DOI: 10.1016/j.neuron.2020.11.004.Peer-Reviewed Original ResearchConceptsPrimary visual cortexVisual cortexTranscallosal pathwayVisual fieldDeficient binocular visionGABAergic chandelier cellsBinocular circuitsBinocular visionChandelier cellsRetinal activityTranscallosal projectionsGeniculocortical inputCallosal activityCenter visual fieldBinocular regionCortexMassive apoptosisDevelopmental assemblyCritical periodV1IpsiBlockadePathwayBinocularityMice
2012
Retinal waves coordinate patterned activity throughout the developing visual system
Ackman JB, Burbridge TJ, Crair MC. Retinal waves coordinate patterned activity throughout the developing visual system. Nature 2012, 490: 219-225. PMID: 23060192, PMCID: PMC3962269, DOI: 10.1038/nature11529.Peer-Reviewed Original ResearchConceptsActivity-dependent developmentSpontaneous retinal activityRetinal wavesRetinal activityEntire visual systemPatterned activitySecondary visual areasPrimary visual cortexOnset of visionCholinergic neurotransmissionNeonatal miceNeuronal activitySpontaneous activityNervous systemVisual cortexVertebrate nervous systemVisual areasVisual systemVisual fieldGenetic factorsEye openingFunctional developmentOnsetActivityNeurotransmission