2019
Rorβ regulates selective axon-target innervation in the mammalian midbrain
Byun H, Lee HL, Liu H, Forrest D, Rudenko A, Kim IJ. Rorβ regulates selective axon-target innervation in the mammalian midbrain. Development 2019, 146: dev171926. PMID: 31332038, PMCID: PMC6679361, DOI: 10.1242/dev.171926.Peer-Reviewed Original ResearchConceptsDorsal lateral geniculate nucleusLateral posterior nucleusLong-range neuronal connectionsSuperior colliculusNeuronal connectionsMammalian midbrainLateral geniculate nucleusThalamic nucleiAxonal projectionsGeniculate nucleusMidbrain centerPosterior nucleusMammalian brainInnervationRORβMidbrainDevelopmental mediatorTranscription factorsColliculusOpposite phenotypeNeuronsBrain
2018
Convergence and Divergence of CRH Amacrine Cells in Mouse Retinal Circuitry
Park SJH, Pottackal J, Ke JB, Jun NY, Rahmani P, Kim IJ, Singer JH, Demb JB. Convergence and Divergence of CRH Amacrine Cells in Mouse Retinal Circuitry. Journal Of Neuroscience 2018, 38: 3753-3766. PMID: 29572434, PMCID: PMC5895998, DOI: 10.1523/jneurosci.2518-17.2018.Peer-Reviewed Original ResearchConceptsAlpha ganglion cellsGanglion cell typesAmacrine cellsGanglion cellsCRH cellsAlpha cellsGABAergic synapsesInhibitory interneuronsExcitation/inhibition balanceCorticotropin-releasing hormoneCre transgenic miceFire action potentialsTonic excitatory driveCell typesBalance of excitationGABA releaseExcitatory circuitsRetinal circuitryExcitatory driveInhibition balanceInhibitory inputsMammalian retinaMouse retinaAction potentialsOptogenetic analyses
2015
Function and Circuitry of VIP+ Interneurons in the Mouse Retina
Park SJ, Borghuis BG, Rahmani P, Zeng Q, Kim IJ, Demb JB. Function and Circuitry of VIP+ Interneurons in the Mouse Retina. Journal Of Neuroscience 2015, 35: 10685-10700. PMID: 26224854, PMCID: PMC4518048, DOI: 10.1523/jneurosci.0222-15.2015.Peer-Reviewed Original ResearchConceptsGanglion cell layerAmacrine cell typesInner nuclear layerAmacrine cellsGanglion cellsINL cellsON pathwayGanglion cell dendritesGanglion cell typesBipolar cell terminalsWhole-cell recordingsCell typesNervous system functionSpatial tuningBipolar cell pathwaysTransgenic mouse lineGCL cellsOptic nerveGABAergic interneuronsRetinal functionCell dendritesRetinal circuitryInhibitory interneuronsNuclear layerBipolar interneurons
2010
Laminar Restriction of Retinal Ganglion Cell Dendrites and Axons: Subtype-Specific Developmental Patterns Revealed with Transgenic Markers
Kim IJ, Zhang Y, Meister M, Sanes JR. Laminar Restriction of Retinal Ganglion Cell Dendrites and Axons: Subtype-Specific Developmental Patterns Revealed with Transgenic Markers. Journal Of Neuroscience 2010, 30: 1452-1462. PMID: 20107072, PMCID: PMC2822471, DOI: 10.1523/jneurosci.4779-09.2010.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsEarly postnatal stagesRGC subsetsSuperior colliculusSubset of RGCsRetinal ganglion cell dendritesPostnatal stagesGanglion cell dendritesInner plexiform layerLateral geniculate nucleusDevelopment of RGCsSpecific sublaminaeDistinct functional signaturesSubpial zoneGanglion cellsPlexiform layerCell dendritesAxonal projectionsDendritic arborsGeniculate nucleusSubtype-specific featuresAxonal arborsRetinorecipient layersMouse transgenic linesDiffuse pattern